|对氨基苯甲酸|CsnPharm

CAS No.: 150-13-0

对氨基苯甲酸 Catalog No. CSN25394

Synonyms: 对氨基苯甲酸;PABA;Vitamin Bx

4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

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400-920-2911

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生物活性

描述3-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi. A one-pot synthesis of superparamagnetic maghemite-based 4-aminobenzoic acid-coated spherical core-shell nanoparticles (PABA@FeNPs) as suitable nanocomposites potentially usable as magnetic carriers for drug delivery. The products consist of well-dispersed maghemite-based nanoparticles of 13 nm average size that represent an easily obtainable system for delivery of highly cytotoxic cisplatin-like complexes in oncological practice^[1]. In addition, PAB (4-aminobenzoic acid) is a safe marker of the completeness of 24 h urine collections. Any collection containing less than 205 out of 240 mg (85%) of PAB, given as 80 mg with each of three meals, is probably incomplete^[2].
参考文献

[1] Starha P, Stavárek M, Tuček J, Trávníček Z. 4-aminobenzoic acid-coated maghemite nanoparticles as potential anticancer drug magnetic carriers: a case study on highly cytotoxic Cisplatin-like complexes involving 7-azaindoles. Molecules. 2014;19(2):1622‐1634. Published 2014 Jan 28
[2] Bingham S, Cummings JH. The use of 4-aminobenzoic acid as a marker to validate the completeness of 24 h urine collections in man. Clin Sci (Lond). 1983;64(6):629‐635

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 7.2920 mL
- 36.4602 mL
- 72.9203 mL
- 5 mM
- 1.4584 mL
- 7.2920 mL
- 14.5841 mL
- 10 mM
- 0.7292 mL
- 3.6460 mL
- 7.2920 mL

技术信息

CAS号

150-13-0

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C7H7NO2

运输

蓝冰

分子量

137.14

别名

对氨基苯甲酸;PABA;Vitamin Bx;Vitamin H1;p-Aminobenzoic acid;4-氨基苯甲酸

溶解度

DMSO	98.0 mg/mL (714.6 mM)
Water	4.0 mg/mL (29.2 mM) warming

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