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CAS No.: 88-04-0

4-Chloro-3,5-dimethylphenol/4-氯-3,5-二甲酚 Catalog No. CSN13068

Synonyms: 4-Chloro-3,5-dimethylphenol;PCMX;HSDB-7427

Chloroxylenol is an antiseptic and disinfectant which is used for skin disinfection and cleaning surgical instruments.

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描述Chloroxylenol is an antimicrobial ingredient that is frequently used in antiseptics/disinfectants for skin (e.g. hand soap) and non-living surfaces^[3]. Triclosan and chloroxylenol decrease the degree of fluidity of membranes and this effect is more pronounced in bacterial membranes^[4]. The toxicological data for chloroxylenol indicate lack of genotoxicity, no evidence of carcinogenicity, and minimal systemic toxicity^[5]. Treatment of S. aureus with the antiseptic chloroxylenol alone did not decrease biofilm cell viability; however, the combination of chloroxylenol and P. aeruginosa supernatant led to a 4-log reduction in S. aureus biofilm viability compared to exposure to chloroxylenol alone^[6].
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT02139033	Keratoconjunctivitis Sicca	Phase 4	Completed	-	United States, Massachusetts ... more >> Andover, Massachusetts, United States, 01810 Collapse <<
NCT01521507	Meibomian Gland Dysfunction ... more >> Dry Eye Collapse <<	Not Applicable	Completed	-	United States, Arkansas ... more >> McDonald Eye Associates Fayetteville, Arkansas, United States, 72703 United States, California Harvard Eye Associates Laguna Hills, California, United States, 92653 United States, Florida Center for Excellence in Eye Care Miami, Florida, United States, 33176 United States, Illinois Chicago Cornea Consultants, Ltd. Hoffman Estates, Illinois, United States, 60169 Jackson Eye Lake Villa, Illinois, United States, 50046 United States, Kentucky Cincinnati Eye Institute - Northern Kentucky Edgewood, Kentucky, United States, 41017 United States, Massachusetts Charles River Eye Associates Winchester, Massachusetts, United States, 01890 United States, Minnesota Associated Eye Care Stillwater, Minnesota, United States, 55082 United States, Missouri Ophthalmology Consultants, Ltd. St. Louis, Missouri, United States, 63131 Collapse <<
NCT01521507	-	-	Completed	-	-

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参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 6.3853 mL
- 31.9265 mL
- 63.8531 mL
- 5 mM
- 1.2771 mL
- 6.3853 mL
- 12.7706 mL
- 10 mM
- 0.6385 mL
- 3.1927 mL
- 6.3853 mL

技术信息

CAS号

88-04-0

储存条件

粉末: Keep in dark place,Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C8H9ClO

运输

蓝冰

分子量

156.61

别名

4-Chloro-3,5-dimethylphenol;PCMX;HSDB-7427;氯二甲酚

溶解度

DMSO	570.0 mg/mL (3639.6 mM)
Water	insoluble

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02139033	Keratoconjunctivitis Sicca	Phase 4	Completed	-	United States, Massachusetts ... more >> Andover, Massachusetts, United States, 01810 Collapse <<
NCT01521507	Meibomian Gland Dysfunction ... more >> Dry Eye Collapse <<	Not Applicable	Completed	-	United States, Arkansas ... more >> McDonald Eye Associates Fayetteville, Arkansas, United States, 72703 United States, California Harvard Eye Associates Laguna Hills, California, United States, 92653 United States, Florida Center for Excellence in Eye Care Miami, Florida, United States, 33176 United States, Illinois Chicago Cornea Consultants, Ltd. Hoffman Estates, Illinois, United States, 60169 Jackson Eye Lake Villa, Illinois, United States, 50046 United States, Kentucky Cincinnati Eye Institute - Northern Kentucky Edgewood, Kentucky, United States, 41017 United States, Massachusetts Charles River Eye Associates Winchester, Massachusetts, United States, 01890 United States, Minnesota Associated Eye Care Stillwater, Minnesota, United States, 55082 United States, Missouri Ophthalmology Consultants, Ltd. St. Louis, Missouri, United States, 63131 Collapse <<
NCT01521507	-	-	Completed	-	-
NCT02500758	-	-	Completed	-	-
NCT03079843	Air Pollution	Not Applicable	Recruiting	September 1, 2020	United States, Michigan ... more >> University of Michigan Recruiting Ann Arbor, Michigan, United States, 48103 Contact: robert bard Collapse <<
NCT02500758	Skin Diseases ... more >> Surgical Site Infection Collapse <<	Not Applicable	Completed	-	-
NCT03544710	Cesarean Wound Disruption With... more >> Postnatal Complication Collapse <<	Not Applicable	Completed	-	Uganda ... more >> Mbarara University of Science and Technology Mbarara, Uganda Collapse <<

4-Chloro-3,5-dimethylphenol/4-氯-3,5-二甲酚 Catalog No. CSN13068

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