CAS No.: 636-00-0
6-羟基多巴胺氢溴酸盐 Catalog No. CSN10153
Synonyms: 6-Hydroxydopamine hydrobromide;6-OHDA hydrobromide;6-OHDA (hydrobromide)
Oxidopamine hydrobromide is a selective catecholaminergic neurotoxin, depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01108029 Parkinson's Disease ... more >> Gait Disorders, Neurologic Collapse << Phase 4 Completed - France ... more >> Devos Lille, France, 59037 Collapse << - 参考文献
- [1] Fujita H, Ogino T, et al. Cell-permeable cAMP analog suppresses 6-hydroxydopamine-induced apoptosis in PC12 cells through the activation of the Akt pathway. Brain Res. 2006 Oct 3;1113(1):10-23.
- [2] Soto-Otero R, Mendez-Alvarez E, et al. Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease. J Neurochem. 2000 Apr;74(4):1605-12.
- [3] Fujita H, Ogino T, Kobuchi H, Fujiwara T, Yano H, Akiyama J, Utsumi K, Sasaki J. Cell-permeable cAMP analog suppresses 6-hydroxydopamine-induced apoptosis in PC12 cells through the activation of the Akt pathway. Brain Res. 2006 Oct 3;1113(1):10-23
- [4] Lin CY, Tsai CW, Tsai CW. Carnosic acid protects SH-SY5Y cells against 6-hydroxydopamine-induced cell death through upregulation of parkin pathway. Neuropharmacology. 2016 Nov;110(Pt A):109-117
- [5] Mahmoudi J, Nayebi AM, Samini M, Reyhani-Rad S, Babapour V. Buspirone improves the anti-cataleptic effect of levodopa in 6-hydroxydopamine-lesioned rats. Pharmacol Rep. 2011;63(4):908-14
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 636-00-0 | 储存条件 |
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| 分子式 | C8H12BrNO3 | 运输 | 蓝冰 | |||||
| 分子量 | 250.09 | 别名 | 6-Hydroxydopamine hydrobromide;6-OHDA hydrobromide;6-OHDA (hydrobromide);6-hydroxy Dopamine;Oxidopamine;2,4,5-Trihydroxyphenethylamine;6-OHDA HBr;6-Hydroxydopamine HBr;6-羟基多巴胺氢溴酸盐 | |||||
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动物实验配方 |
