|5-氨基-2,3-二氢-1,4-酞嗪二酮|CsnPharm

CAS No.: 521-31-3

鲁米诺 Catalog No. CSN17295

Synonyms: Diogenes reagent;3-Aminophthalhydrazide;NSC-5064

Luminol is a chemical with chemiluminescence property, soluble in most polar organic solvents, insoluble in water. When mixed with an appropriate oxidizing agent, it emits a blue glow.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Luminol is a major probe for chemiluminescence (CL) and electrochemiluminescence (ECL) detection technologies in (bio)analysis. LCL (luminol chemiluminescence) is a very useful detection method due to its selectivity, simplicity, low cost, and high sensitivity. LCL has a dynamic range of applications, including quantification and detection of macro and micromolecules such as proteins, carbohydrates, DNA, and RNA. Luminol-based methods are used in environmental monitoring as biosensors, in the pharmaceutical industry for cellular localization and as biological tracers, and in reporter gene-based assays and several other immunoassays^[1]. Moreover, a significant peak in chemiluminescence production in a particle-free system occurs between 5 and 15 min following exposure of cells to micromolar concentrations of luminol. The response is directly related to dose over a wide rane of luminol concentrations and can be inhibited by superoxide dismutase (90%), catalase (100%) and sodium azide (40%). The effect of luminol eliciting a peak in neutrophil chemiluminescence is mediated within intact cells rather than at the cell membrane. Luminol may produce a peak in chemiluminescence by stimulating very low levels of hexose monophosphate shunt activity and superoxide generation or it may simply amplify light production generated by the production of excited oxygen radicals resulting from surface interactions^[2].
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01848379	Chronic Periodontitis ... more >> Diabetes Mellitus, Type 2 Collapse <<	Not Applicable	Active, not recruiting	December 2017	Germany ... more >> Department of Periodontontology, ZentrumZMK Giessen, Germany, 35392 Collapse <<
NCT01991990	-	-	Completed	-	-
NCT01195272	Rheumatoid Arthritis	Phase 4	Completed	-	United Kingdom ... more >> Liverpool, United Kingdom, L9 7AL Collapse <<

更多
参考文献

[1] Khan P, Idrees D, Moxley MA, Corbett JA, Ahmad F, von Figura G, Sly WS, Waheed A, Hassan MI. Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses. Appl Biochem Biotechnol. 2014 May;173(2):333-55.
[2] Allred CD, Margetts J, Hill HR. Luminol-induced neutrophil chemiluminescence. Biochim Biophys Acta. 1980 Aug 13;631(2):380-5.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 5.6446 mL
- 28.2231 mL
- 56.4461 mL
- 5 mM
- 1.1289 mL
- 5.6446 mL
- 11.2892 mL
- 10 mM
- 0.5645 mL
- 2.8223 mL
- 5.6446 mL

技术信息

CAS号

521-31-3

储存条件

粉末: Keep in dark place,Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C8H7N3O2

运输

蓝冰

分子量

177.16

别名

Diogenes reagent;3-Aminophthalhydrazide;NSC-5064;鲁米诺

溶解度

DMSO	30.0 mg/mL (169.3 mM)

动物实验配方

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

鲁米诺 Catalog No. CSN17295

靶点选择性

请登录您的专属账户

确认信息