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CAS No.: 259793-96-9
Synonyms: T-705;T 705;Favilavir
Favipiravir is an anti-viral compound with activity against many RNA viruses and an RNA-directed RNA polymerase NS5B inhibitor.
生物活性
动物研究 | |||||||||||||||||
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给药途径 | p.o. | ||||||||||||||||
动物药代数据 |
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NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01728753 | Influenza | Phase 1 Phase 2 | Completed | - | United States, Florida ... more >> Miami Research Associates Miami, Florida, United States, 33143 Collapse << |
NCT02662855 | Ebola Virus Disease | Phase 2 | Completed | - | - |
NCT01068912 | Influenza | Phase 2 | Completed | - | - |
实验方案
技术信息
CAS号 | 259793-96-9 | 储存条件 |
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分子式 | C5H4FN3O2 | 运输 | 蓝冰 | |||||
分子量 | 157.10 | 别名 | T-705;T 705;Favilavir;Avigan | |||||
溶解度 |
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动物实验配方 |
Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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MDCK cells | - | Function assay | - | Inhibition of viral replication of influenza A virus (A/Hong Kong/213/03(H5N1)) and influenza A virus (A/Ann Arbor/6/60(H2N2)) hybrid virus in MDCK cells by neutral red uptake assay | 17194832 |
MDCK cells | - | Function assay | - | Inhibition of influenza A virus (A/duck/Minnesota/1525/1981 (H5N1)) replication in MDCK cells by neutral red uptake assay | 17194832 |
Vero cells | - | Function assay | 7-8 days | Antiviral activity against Junin virus Candid-1 in Vero cells assessed as inhibition of virus-induced visual cytopathic effect after 7 to 8 days | 17606691 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01728753 | Influenza | Phase 1 Phase 2 | Completed | - | United States, Florida ... more >> Miami Research Associates Miami, Florida, United States, 33143 Collapse << |
NCT02662855 | Ebola Virus Disease | Phase 2 | Completed | - | - |
NCT01068912 | Influenza | Phase 2 | Completed | - | - |
NCT02008344 | Influenza | Phase 3 | Completed | - | - |
NCT02026349 | Influenza | Phase 3 | Completed | - | - |
NCT02739477 | Ebola Virus Survivor | Phase 2 | Terminated(End date of epidemi... more >>c) Collapse << | - | Guinea ... more >> Conakry Conakry, Guinea Nzérékoré Nzérékoré, Guinea Collapse << |
NCT03394209 | Influenza, Human ... more >> Critical Illness Influenza Collapse << | Phase 2 | Recruiting | December 10, 2018 | China ... more >> China-Japan Friendship Hospital Recruiting Beijing, China, 100029 Contact: Bin Cao, Ph.D 86 010 84206264 caobin_ben@163.com Contact: Yeming Wang, Ph.D 86 18810663558 wwyymm_love@163.com Principal Investigator: Bin Cao, Ph.D Collapse << |
NCT02329054 | Ebola Virus Disease | Phase 2 | Completed | - | Guinea ... more >> The caregivers treatment center Conakry, Guinea MSF Ebola treatment centre Gueckedou, Guinea French Red Cross Ebola care center Macenta, Guinea ALIMA Ebola care center Nzerekore, Guinea Collapse << |
NCT01068912 | - | - | Completed | - | - |
NCT01419457 | Healthy Hepat... more >>ic Impairment Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> University of Miami Miami, Florida, United States Orlando Clinical Research Center Orlando, Florida, United States Collapse << |
靶点 | Description | IC50 |
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