CAS No.: 105454-04-4
7-epi-Taxol/7-表紫杉醇 Catalog No. CSN13461
Synonyms: 7-epi-Paclitaxel;7-表紫杉醇
7-Epitaxol is a natural product isolated and purified from the barks of Taxus chinensis (Pilger) Rehd. which is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Royer I, Alvinerie P, et al. Paclitaxel metabolites in human plasma and urine: identification of 6 alpha-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry. Rapid Commun Mass Spectrom. 1995;9(6):495-502.
- [2] Ringel I, Horwitz SB. Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium. J Pharmacol Exp Ther. 1987 Aug;242(2):692-8.
- [3] Meng Z, Lv Q, Lu J, Yao H, Lv X, Jiang F, Lu A, Zhang G. Prodrug Strategies for Paclitaxel. Int J Mol Sci. 2016 May 23;17(5):796. doi: 10.3390/ijms17050796. PMID: 27223283; PMCID: PMC4881612.
- [4] Duhamel M, Rose M, Rodet F, Murgoci AN, Zografidou L, Régnier-Vigouroux A, Vanden Abeele F, Kobeissy F, Nataf S, Pays L, Wisztorski M, Cizkova D, Fournier I, Salzet M. Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies. Mol Cell Proteomics. 2018 Jun;17(6):1126-1143. doi: 10.1074/mcp.RA117.000443. Epub 2018 Mar 12. PMID: 29531019; PMCID: PMC5986247.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 105454-04-4 | 储存条件 |
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| 分子式 | C47H51NO14 | 运输 | 蓝冰 | |||
| 分子量 | 853.91 | 别名 | 7-epi-Paclitaxel;7-表紫杉醇 | |||
| 溶解度 |
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动物实验配方 |
