CAS No.: 1397-89-3
两性霉素B Catalog No. CSN10299
Synonyms: NSC 527017;LNS-AmB;Fungizone
Amphotericin B is a polyene, antifungal antibiotic produced from a strain of Streptomyces nodosus.
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00163111 Candidiasis Phase 3 Completed - - NCT00370825 Visceral Leishmaniasis Phase 2 Completed - India ... more >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Collapse << NCT00002742 Chronic Myeloproliferative Dis... more >>orders Infection Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Collapse << Phase 3 Completed - - - 更多
- 参考文献
- [1] Sau K, Mambula SS, Latz E, Henneke P, Golenbock DT, Levitz SM. The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism. J Biol Chem. 2003;278(39):37561‐37568
- [2] Barwicz J, Tancrede P. The effect of aggregation state of amphotericin-B on its interactions with cholesterol- or ergosterol-containing phosphatidylcholine monolayers. Chem Phys Lipids. 1997 Feb 28;85(2):145-55.
- [3] Ramos H, Valdivieso E, Gamargo M, Dagger F, Cohen BE. Amphotericin B kills unicellular leishmanias by forming aqueous pores permeable to small cations and anions. J Membr Biol. 1996;152(1):65‐75
- [4] Demaimay R, Adjou K, Lasmézas C, et al. Pharmacological studies of a new derivative of amphotericin B, MS-8209, in mouse and hamster scrapie. J Gen Virol. 1994;75 ( Pt 9):2499‐2503
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1397-89-3 | 储存条件 |
|
|||||||||||||
| 分子式 | C47H73NO17 | 运输 | 蓝冰 | |||||||||||||
| 分子量 | 924.08 | 别名 | NSC 527017;LNS-AmB;Fungizone;两性霉素B | |||||||||||||
| 溶解度 |
|
动物实验配方 |
|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00163111 | Candidiasis | Phase 3 | Completed | - | - |
| NCT00370825 | Visceral Leishmaniasis | Phase 2 | Completed | - | India ... more >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Collapse << |
| NCT00002742 | Chronic Myeloproliferative Dis... more >>orders Infection Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Collapse << | Phase 3 | Completed | - | - |
| NCT00037206 | Aspergillosis | Phase 2 Phase 3 | Completed | - | United States, Pennsylvania ... more >> Versicor, Inc. King of Prussia, Pennsylvania, United States, 19406 Collapse << |
| NCT00419770 | Mucormycosis | Phase 2 | Completed | - | United States, California ... more >> City of Hope National Medical Center Duarte, California, United States, 91010 UCSF San Francisco, California, United States, 94143 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 United States, Ohio Summa Health Systems Akron, Ohio, United States, 44304 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 United States, Washington Fred Hutchinson Cancer Research Center Seattle, Washington, United States, 98109 Collapse << |
| NCT00847678 | Cryptococcal Meningitis | Phase 2 | Terminated | - | South Africa ... more >> Novartis Investigative Site South Africa, South Africa Collapse << |
| NCT00362544 | Leukemia | Phase 4 | Completed | - | France ... more >> Gilead Sciences Paris, France, 75015 Collapse << |
| NCT00889356 | Candidiasis B... more >>acterial Vaginosis Collapse << | Phase 3 | Unknown | March 2010 | Brazil ... more >> Vox Femina Not yet recruiting Jundiaí, SP, Brazil Contact: Rogerio Bonassi Machado, MD Principal Investigator: Rogerio Bonassi Machado, MD Collapse << |
| NCT00419770 | - | - | Completed | - | - |
| NCT01843309 | Patients With Fungic Infection... more >>s Collapse << | Phase 4 | Terminated(Not possible to com... more >>plete the sample within the estimated time by the use of new antifungals) Collapse << | - | Mexico ... more >> Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán México, Mexico, 14000 Collapse << |
| NCT00002306 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | United States, Alabama ... more >> Univ of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, District of Columbia George Washington Univ Med Ctr Washington, District of Columbia, United States, 20037 United States, Florida Univ of South Florida Tampa, Florida, United States, 33612 United States, Georgia Emory Univ School of Medicine Atlanta, Georgia, United States, 30303 Med College of Georgia Augusta, Georgia, United States, 30912 United States, Massachusetts Univ Hosp Boston, Massachusetts, United States, 02118 United States, Michigan Ann Arbor Veterans Administration Med Ctr Ann Arbor, Michigan, United States, 48105 United States, Missouri Washington Univ School of Medicine St. Louis, Missouri, United States, 63108 United States, New York Bronx Veterans Administration / Mount Sinai Hosp Bronx, New York, United States, 10468 Saint Luke's - Roosevelt Hosp Ctr New York, New York, United States, 10025 United States, Ohio Cincinnati Veterans Adm Med Ctr / Univ Hosp Cincinnati, Ohio, United States, 452670405 United States, Texas United States Air Force Med Ctr Lackland Air Force Base, Texas, United States, 782365300 Southwest Texas Methodist Hosp San Antonio, Texas, United States, 78229 Univ TX San Antonio Health Science Ctr San Antonio, Texas, United States, 78284 Collapse << |
| NCT00003315 | Infection | Phase 3 | Completed | - | United Kingdom ... more >> University of Wales College of Medicine Cardiff, Wales, United Kingdom, CF4 4XN Collapse << |
| NCT01656382 | Invasive Cryptococcosis | Phase 4 | Completed | - | United States, District of Col... more >>umbia Washington Hospital Center Washington, District of Columbia, United States, 20010 Collapse << |
| NCT00000639 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | United States, California ... more >> USC CRS Los Angeles, California, United States, 90033 Ucsf Aids Crs San Francisco, California, United States, 94110 United States, Florida Univ. of Miami AIDS CRS Miami, Florida, United States, 33136 United States, Hawaii Univ. of Hawaii at Manoa, Leahi Hosp. Honolulu, Hawaii, United States United States, Illinois Northwestern University CRS Chicago, Illinois, United States, 60611 United States, Indiana Indiana Univ. School of Medicine, Infectious Disease Research Clinic Indianapolis, Indiana, United States, 46202 Methodist Hosp. of Indiana Indianapolis, Indiana, United States, 46202 United States, Louisiana Tulane Med. Ctr. - Charity Hosp. of New Orleans, ACTU New Orleans, Louisiana, United States, 70112 United States, Massachusetts Massachusetts General Hospital ACTG CRS Boston, Massachusetts, United States, 02114 Bmc Actg Crs Boston, Massachusetts, United States, 02118 Beth Israel Deaconess Med. Ctr., ACTG CRS Boston, Massachusetts, United States, 02215 United States, Missouri St. Louis ConnectCare, Infectious Diseases Clinic St Louis, Missouri, United States Washington U CRS St. Louis, Missouri, United States United States, New York SUNY - Buffalo, Erie County Medical Ctr. Buffalo, New York, United States, 14215 Beth Israel Med. Ctr. (Mt. Sinai) New York, New York, United States, 10003 Cornell University A2201 New York, New York, United States, 10021 Univ. of Rochester ACTG CRS Rochester, New York, United States, 14642 United States, North Carolina Unc Aids Crs Chapel Hill, North Carolina, United States, 27599 Carolinas HealthCare System, Carolinas Med. Ctr. Charlotte, North Carolina, United States Regional Center for Infectious Disease, Wendover Medical Center CRS Greensboro, North Carolina, United States, 27401 United States, Ohio Univ. of Cincinnati CRS Cincinnati, Ohio, United States, 45267 The Ohio State Univ. AIDS CRS Columbus, Ohio, United States, 43210 United States, Pennsylvania Hosp. of the Univ. of Pennsylvania CRS Philadelphia, Pennsylvania, United States, 19104 Pitt CRS Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00697944 | Sepsis Candid... more >>a Collapse << | Phase 4 | Unknown | March 2009 | France ... more >> Chu Michallon Recruiting Grenoble, France, 38000 Contact: TIMSIT jftimsit@chu-grenoble.fr Hopital Saint Louis Not yet recruiting Paris, France, 75010 Collapse << |
| NCT03399955 | PKDL - Post-Kala-Azar Dermal L... more >>eishmanioid Collapse << | Phase 2 | Recruiting | May 1, 2022 | Sudan ... more >> Prof. Elhassan Centre for tropical Medicine Recruiting Doka, Gedaref, Sudan Contact: Brima Musa, MD Collapse << |
| NCT00158730 | Invasive Aspergillosis ... more >> Other Fungal Infections Collapse << | Phase 3 | Completed | - | - |
| NCT00381394 | Leishmaniasis, Visceral | Phase 2 | Completed | - | India ... more >> GSK Investigational Site Muzaffarpur, India, 842001 GSK Investigational Site Muzaffarpur, India GSK Investigational Site Patna, India, 800007 Collapse << |
| NCT00986713 | Invasive Pulmonary Aspergillos... more >>is Collapse << | Phase 4 | Unknown | October 2010 | China, Beijing ... more >> Beijing Chaoyang Hospital,Affiliate of Capital Medical University Recruiting Beijing, Beijing, China, 100020 Contact: Bin Cao, doctor 8610-85231130 caobin1999@gmail.com Collapse << |
| NCT00082537 | Neutropenia F... more >>ever Collapse << | Phase 2 | Completed | - | - |
| NCT01067443 | Primary Visceral Leishmaniasis | Phase 2 | Completed | - | Kenya ... more >> Kimalel Health Centre Kimalel, Kenya Sudan Kassab Hospital Kassab, Gedaref, Sudan El Hassan Centre for Tropical Medicine Doka, Gedarif, Sudan Collapse << |
| NCT03577509 | Invasive Fungal Disease | Phase 1 | Completed | - | China, Shanghai ... more >> Huashan Hospital Affiliated to Fudan University Shanghai, Shanghai, China, 200040 Collapse << |
| NCT00334412 | Invasive Aspergillosis | Phase 4 | Completed | - | France ... more >> Gilead Sciences Paris, France, 75015 Collapse << |
| NCT00523965 | Leishmaniasis, Visceral | Phase 3 | Completed | - | India ... more >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Collapse << |
| NCT00002305 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | - |
| NCT03112031 | Meningitis Streptococcal ... more >> Hiv Meningitis Meningoencephalitis Collapse << | Phase 2 | Recruiting | December 2020 | Vietnam ... more >> Cho Ray Hospital Recruiting Ho Chi Minh City, Vietnam Principal Investigator: Hung Le Quoc, MD Sub-Investigator: Ngan Nguyen Thi Thuy, MD Sub-Investigator: Binh Tran Quang, MD Hospital for Tropical Diseases Recruiting Ho Chi Minh City, Vietnam Principal Investigator: Tung Nguyen Le Nhu, MD Sub-Investigator: Mai Nguyen Thi Hoang, MD Sub-Investigator: Lan Nguyen Phu Huong, MD Sub-Investigator: Tai Luong Thi Hue, MD Sub-Investigator: Phu Nguyen Hoan, MD Sub-Investigator: Chau Nguyen Van Vinh, MD Oxford University Clinical Research Unit Active, not recruiting Ho Chi Minh City, Vietnam Collapse << |
| NCT01857479 | Allergic Bronchopulmonary Aspe... more >>rgillosis Collapse << | Phase 2 Phase 3 | Completed | - | India ... more >> Chest Clinic, PGIMER Chandigarh, India, 160012 Collapse << |
| NCT00000708 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | United States, Florida ... more >> Univ of Miami School of Medicine Miami, Florida, United States, 331361013 United States, Louisiana Tulane Univ School of Medicine New Orleans, Louisiana, United States, 70112 United States, New York Bronx Municipal Hosp Ctr/Jacobi Med Ctr Bronx, New York, United States, 10461 Mem Sloan - Kettering Cancer Ctr New York, New York, United States, 10021 United States, North Carolina Univ of North Carolina Chapel Hill, North Carolina, United States, 275997215 United States, South Carolina Julio Arroyo West Columbia, South Carolina, United States, 29169 Collapse << |
| NCT00326157 | Fungus Diseases | Phase 2 | Completed | - | Italy ... more >> Gilead Sciences Milan, Italy, 20146 Collapse << |
| NCT00002075 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | United States, California ... more >> Dr Robert Larsen Los Angeles, California, United States, 90033 Collapse << |
| NCT00002159 | HIV Infections ... more >> Histoplasmosis Blastomycosis Collapse << | Phase 3 | Completed | - | United States, Alabama ... more >> UAB Station / Infectious Division Birmingham, Alabama, United States, 35294 United States, Arkansas Univ of Arkansas for Med Sciences Little Rock, Arkansas, United States, 72205 United States, Georgia Division of Infectious Diseases Atlanta, Georgia, United States, 30303 United States, Indiana Division of Inf Diseases/ Indiana Univ Hosp Indianapolis, Indiana, United States, 46202 Community Hosp Indianapolis, Indiana, United States, 46218 United States, Louisiana LSU Med Ctr / Div of Pulmonary & Critical Care Med Shreveport, Louisiana, United States, 71130 United States, Michigan Ann Arbor Veterans Administration Med Ctr Ann Arbor, Michigan, United States, 48105 United States, Missouri Univ of Missouri / Division of Infectious Diseases Kansas City, Missouri, United States, 641082792 Infectious Diseases Association / Research Med Ctr Kansas City, Missouri, United States, 64132 Collapse << |
| NCT00003031 | Infection Pul... more >>monary Complications Collapse << | Phase 3 | Completed | - | - |
| NCT00670657 | Candidemia In... more >>vasive Candidiasis Collapse << | Phase 4 | Completed | - | Italy ... more >> Gilead Sciences Srl Milan, Italy, 20146 Collapse << |
| NCT00624143 | Pediatric Acute Leukemia Induc... more >>tion Collapse << | Phase 3 | Unknown | - | India ... more >> Institute Rotary Cancer Hospital, All India Institute of Medical Sciences Recruiting New Delhi, Delhi, India, 110029 Contact: SAMEER BAKHSHI, MD 91-11-26588153 sambakh@hotmail.com Collapse << |
| NCT00008359 | Cancer | Phase 3 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Collapse << |
| NCT00750737 | Invasive Fungal Infections ... more >> Hematologic Malignancies Collapse << | Phase 3 | Completed | - | United States, Texas ... more >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00391014 | Acute Myeloid Leukemia ... more >> Allogeneic Haematopoietic Progenitor Cell Transplant Collapse << | Phase 2 | Completed | - | Spain ... more >> Hospital de la Santa Creu i Sant Pau Barcelona, Spain Hospital Universitario de la Princesa Madrid, Spain Hospital Universitario de Salamanca Salamanca, Spain Hospital Universitario la Fe Valencia, Spain Collapse << |
| NCT00001646 | Acquired Immunodeficiency Synd... more >>rome Aspergillosis HIV Infections Immunologic Deficiency Syndromes Neutropenia Collapse << | Phase 3 | Completed | - | United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00001017 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Phase 3 | Completed | - | United States, California ... more >> UCLA CARE Ctr Los Angeles, California, United States, 90095 United States, Florida Univ of Miami School of Medicine Miami, Florida, United States, 331361013 United States, Indiana Indiana Univ Hosp Indianapolis, Indiana, United States, 462025250 United States, Louisiana Louisiana State Univ School of Medicine New Orleans, Louisiana, United States, 70112 Tulane Univ School of Medicine New Orleans, Louisiana, United States, 70112 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 United States, Massachusetts Harvard (Massachusetts Gen Hosp) Boston, Massachusetts, United States, 02114 Beth Israel Deaconess - West Campus Boston, Massachusetts, United States, 02215 United States, New York Jack Weiler Hosp / Bronx Municipal Hosp Bronx, New York, United States, 10465 Montefiore Med Ctr / Bronx Municipal Hosp Bronx, New York, United States, 10467 North Central Bronx Hosp / Bronx Municipal Hosp Bronx, New York, United States, 10467 Bronx Veterans Administration / Mount Sinai Hosp Bronx, New York, United States, 10468 SUNY / Erie County Med Ctr at Buffalo Buffalo, New York, United States, 14215 City Hosp Ctr at Elmhurst / Mount Sinai Hosp Elmhurst, New York, United States, 11373 Beth Israel Med Ctr / Peter Krueger Clinic New York, New York, United States, 10003 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 Cornell Univ Med Ctr New York, New York, United States, 10021 Mem Sloan - Kettering Cancer Ctr New York, New York, United States, 10021 Saint Luke's - Roosevelt Hosp Ctr New York, New York, United States, 10025 Mount Sinai Med Ctr New York, New York, United States, 10029 Univ of Rochester Medical Center Rochester, New York, United States, 14642 SUNY - Stony Brook Stony Brook, New York, United States, 117948153 United States, North Carolina Univ of North Carolina Chapel Hill, North Carolina, United States, 275997215 Duke Univ Med Ctr Durham, North Carolina, United States, 27710 United States, Ohio Holmes Hosp / Univ of Cincinnati Med Ctr Cincinnati, Ohio, United States, 452670405 Univ Hosp of Cleveland / Case Western Reserve Univ Cleveland, Ohio, United States, 44106 Ohio State Univ Hosp Clinic Columbus, Ohio, United States, 432101228 United States, South Carolina Julio Arroyo West Columbia, South Carolina, United States, 29169 Collapse << |
| NCT00002074 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | - |
| NCT00002316 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Phase 1 | Completed | - | United States, California ... more >> Los Angeles County - USC Med Ctr Los Angeles, California, United States, 90033 UCI Med Ctr Orange, California, United States, 92668 UCSD Treatment Ctr San Diego, California, United States, 92103 United States, Kansas Univ of Kansas School of Medicine Wichita, Kansas, United States, 67214 United States, New York SUNY / Health Sciences Ctr at Stony Brook Stony Brook, New York, United States, 117948153 United States, North Carolina Duke Univ Med Ctr Durham, North Carolina, United States, 27710 East Carolina Univ School of Medicine Greenville, North Carolina, United States, 278584354 Bowman Gray School of Medicine Winston Salem, North Carolina, United States, 271571042 United States, Ohio Case Western Reserve Univ Cleveland, Ohio, United States, 44106 United States, Pennsylvania Pennsylvania State Univ / Hershey Med Ctr Hershey, Pennsylvania, United States, 17033 United States, Texas Univ TX Galveston Med Branch Galveston, Texas, United States, 775550882 Collapse << |
| NCT00235651 | Lung Transplantation ... more >> Lung Diseases Collapse << | Phase 3 | Terminated(study completed) | - | United States, Pennsylvania ... more >> University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00750737 | - | - | Completed | - | - |
| NCT00002068 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | United States, California ... more >> Davies Med Ctr San Francisco, California, United States, 94114 United States, Delaware Christiana Hosp / Med Ctr of Delaware Wilmington, Delaware, United States, 19899 United States, Florida Univ of South Florida Tampa, Florida, United States, 33612 United States, Maryland Univ of Maryland / Inst of Human Virology Baltimore, Maryland, United States, 212011192 United States, Michigan Henry Ford Hosp Detroit, Michigan, United States, 48202 United States, New York Harlem AIDS Treatment Group / Harlem Hosp Ctr New York, New York, United States, 10037 United States, Tennessee Univ of Tennessee Memphis, Tennessee, United States, 38163 Canada, Ontario Saint Michael's Hosp Toronto, Ontario, Canada Collapse << |
| NCT00386997 | Fungal Infection | Phase 4 | Terminated(Study closed due to... more >> recruitment challenges.) Collapse << | - | Germany ... more >> Gilead Sciences GmbH Martinsried/Munich, Germany, 82152 Collapse << |
| NCT02527928 | - | - | Unknown | February 2016 | - |
| NCT00002277 | Mycoses HIV I... more >>nfections Collapse << | Phase 3 | Completed | - | United States, Texas ... more >> Dr Layne Gentry Houston, Texas, United States, 77030 Dr Temple Williams Houston, Texas, United States, 77030 M D Anderson Cancer Ctr Houston, Texas, United States, 77030 Collapse << |
| NCT00106288 | Candidiasis | Phase 3 | Completed | - | - |
| NCT01122771 | Visceral Leishmaniasis | Phase 3 | Completed | - | Bangladesh ... more >> Bhaluka UZHC Bhaluka, Mymensingh, Bangladesh Gaffargaon Gaffargaon, Mymensingh, Bangladesh Community Based Medical College Trishal, Mymensingh, Bangladesh Trishal UZHC Trishal, Mymensingh, Bangladesh Collapse << |
| NCT00263315 | Aspergillosis | Phase 2 Phase 3 | Completed | - | Netherlands ... more >> Erasmus MC centrumlocatie Rotterdam, Netherlands Erasmus MC locatie Daniel den Hoed Rotterdam, Netherlands Collapse << |
| NCT00003938 | Cancer | Phase 3 | Completed | - | - |
| NCT01293643 | Vaginosis, Bacterial ... more >> Candidiasis, Vulvovaginal Collapse << | Phase 3 | Completed | - | - |
| NCT00936910 | Central Line Fungal Infections | Phase 4 | Completed | - | United States, Pennsylvania ... more >> Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania, United States, 15224 Collapse << |
| NCT00936910 | - | - | Completed | - | - |
| NCT00047827 | Aspergillosis | Phase 2 | Terminated(Inadequate enrollme... more >>nt) Collapse << | - | United States, District of Col... more >>umbia Washington, District of Columbia, United States, 20010 United States, Georgia Atlanta, Georgia, United States, 30322 United States, Michigan Ann Arbor, Michigan, United States, 48109 Detroit, Michigan, United States, 48201 United States, Missouri St. Louis, Missouri, United States, 63110 United States, Tennessee Memphis, Tennessee, United States, 38105 United States, Texas Houston, Texas, United States, 77030 Collapse << |
| NCT00002019 | Meningitis, Cryptococcal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | United States, California ... more >> Harbor - UCLA Med Ctr Torrance, California, United States, 90502 United States, Connecticut Dr Thomas Patterson New Haven, Connecticut, United States, 06510 United States, District of Columbia Walter Reed Army Med Ctr Washington, District of Columbia, United States, 203075001 United States, Illinois Rush Presbyterian - Saint Luke's Med Ctr Chicago, Illinois, United States, 60612 United States, Maryland Natl Naval Med Ctr Bethesda, Maryland, United States, 20889 United States, Massachusetts Univ Hosp Boston, Massachusetts, United States, 02118 United States, New Jersey East Orange Veterans Administration Med Ctr East Orange, New Jersey, United States, 07018 Saint Michael's Med Ctr Newark, New Jersey, United States, 07102 United States, New York Beth Israel Med Ctr / Peter Krueger Clinic New York, New York, United States, 10003 Dr Dorothy Friedberg New York, New York, United States, 10016 New York Univ Med Ctr New York, New York, United States, 10016 Cornell Univ Med College New York, New York, United States, 10021 Saint Luke's - Roosevelt Hosp Ctr New York, New York, United States, 10025 Mount Sinai Med Ctr / Jack Martin Fund Clinic New York, New York, United States, 10029 Mount Sinai Med Ctr New York, New York, United States, 10029 United States, Pennsylvania Buckley Braffman Stern Med Associates Philadelphia, Pennsylvania, United States, 19107 United States, Texas Univ TX Galveston Med Branch Galveston, Texas, United States, 77550 Audie L Murphy Veterans Administration Hosp San Antonio, Texas, United States, 78284 United States, Utah Univ of Utah School of Medicine Salt Lake City, Utah, United States, 84132 Collapse << |
| NCT00161356 | Liver Transplantation | Phase 4 | Terminated(Budget issues) | - | United States, Texas ... more >> Memorial Hermann Hospital Houston, Texas, United States, 77030 Collapse << |
| NCT00145249 | Cryptococcal Meningitis | Phase 2 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35255 United States, California University of Southern California Los Angeles, California, United States, 90033 Harbor-UCLA Medical Center Los Angeles, California, United States, 90502 United States, Colorado University of Colorado Denver, Colorado, United States, 80291-0238 United States, Florida University of Florida Gainesville, Florida, United States, 32610 University of Miami Miami, Florida, United States, 33136-1096 United States, Louisiana Tulane University Health Sciences Center New Orleans, Louisiana, United States, 70112 United States, Michigan Harper University Hospital Detroit, Michigan, United States, 48201 United States, Texas Texas Medical Center - Michael E. DeBakey Veterans Affairs Houston, Texas, United States, 77030 The University of Texas Health Science Center at Houston Houston, Texas, United States, 77030 Thailand Ramathibodi Hospital, Mahidol University Bangkok, Thailand, 10400 Mahidol University - Siriraj Hospital - Medicine Bangkok, Thailand, 10700 Chiang Mai University Chiang Mai, Thailand, 50200 Khon Kaen University Khon Kaen, Thailand, 40002 Bamrasnaradura Institution Nonthaburi, Thailand, 11000 Collapse << |
| NCT00001065 | Candidiasis, Oral ... more >> HIV Infections Collapse << | Phase 2 | Completed | - | - |
| NCT01437020 | Leishmaniasis ... more >> Effects of Immunotherapy Collapse << | Phase 1 Phase 2 | Withdrawn(Drug Product no long... more >>er available.) Collapse << | - | India ... more >> Kala-Azar Medical Research Center (KAMRC), Rambag Road Muzaffarpur, India Banaras Hindu University Varanasi, India Collapse << |
| NCT00002041 | Candidiasis, Esophageal ... more >> HIV Infections Collapse << | Not Applicable | Completed | - | United States, New Jersey ... more >> Bristol - Myers Squibb Co Princeton, New Jersey, United States, 085434000 Collapse << |
| NCT00451711 | Acute Myeloid Leukemia | Phase 2 | Unknown | October 2014 | Australia, Victoria ... more >> The Alfred Hosptial Not yet recruiting Melbourne, Victoria, Australia, 3004 Principal Investigator: C. Orla Morrissey, MB, BCh, FRACP Principal Investigator: Anthony P Schwarer, MB, BS, FRACP, MD, FRCPA Sub-Investigator: Sushrat Patil, MB, BS, FRACP, FRCPA Box Hill Hospital, Eastern Health Recruiting Melbourne, Victoria, Australia, 3129 Contact: Anthony P Schwarer, MB, BS, FRACP, MD, FRCPA +61 3 9895 3333 anthony.schwarer@boxhill.org.au Principal Investigator: Anthony P. Schwarer, MB, BS, FRACP, MD, FRCPA Collapse << |
| NCT02971007 | Vulvovaginitis ... more >> Yeast Infection Yeast Infection Vaginal Candidiasis, Vulvovaginal Collapse << | Phase 2 | Completed | - | - |
| NCT01254708 | Lung Transplant Recipient | Phase 2 | Suspended(Study has been place... more >>d on hold due to unavailability of funding.) Collapse << | January 2014 | Canada, Ontario ... more >> University Health Network/ Toronto General Hospital Toronto, Ontario, Canada, M5G 2N2 Collapse << |
| NCT02971007 | - | - | Completed | - | - |
| NCT03187691 | Acute Myeloid Leukemia ... more >> Acute Lymphoblastic Leukemia Collapse << | Phase 2 | Not yet recruiting | April 2020 | - |
| NCT00145249 | - | - | Completed | - | - |
| NCT00310505 | Visceral Leishmaniasis | Not Applicable | Completed | - | India ... more >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 221005 Collapse << |
| NCT02273661 | Allergic Bronchopulmonary Aspe... more >>rgillosis Collapse << | Phase 2 | Active, not recruiting | February 19, 2020 | France ... more >> Chu de Poitiers Poitiers, France, 86000 Collapse << |
| NCT00497601 | Visceral Leishmaniasis | Phase 2 | Completed | - | India ... more >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Collapse << |
| NCT03656081 | Chronic Pulmonary Aspergillosi... more >>s Collapse << | Phase 3 | Not yet recruiting | May 2023 | - |
| NCT00421187 | Febrile Neutropenia | Phase 4 | Terminated(Unable to recruit s... more >>ubjects in the Turkey site.) Collapse << | - | Greece ... more >> Gilead Sciences Athens, Greece, 167 77 Collapse << |
| NCT03529617 | - | - | Recruiting | December 31, 2020 | Belgium ... more >> UZ Leuven Recruiting Leuven, Belgium, 3000 Contact: Ruth Van Daele, PharmD +3216343264 ruth.vandaele@uzleuven.be Collapse << |
| NCT00418951 | - | - | Completed | - | - |
| NCT00418951 | Acute Myelogenous Leukemia ... more >> Myelodysplastic Syndrome Collapse << | Phase 2 | Completed | - | United States, Texas ... more >> The University of Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00148148 | Hematopoietic Stem Cell Transp... more >>lantation Fungus Diseases Collapse << | Phase 2 | Completed | - | Germany ... more >> KKS Münster University Hospital Münster, NRW, Germany, 48145 Collapse << |
| NCT03167957 | Vulvovaginal Candidiases ... more >> Yeast Infection Vulvovaginitis Yeast Infection Vaginal Candidiasis, Vulvovaginal Collapse << | Phase 2 | Not yet recruiting | June 2019 | United States, Michigan ... more >> Tolan Park Clinic Not yet recruiting Detroit, Michigan, United States, 48201 Principal Investigator: Jack D Sobel, MD Collapse << |
| NCT01945281 | Candidiasis, Invasive | Phase 2 | Terminated(Operational feasibi... more >>lity with low recruitment due to changing epidemiology of disease) Collapse << | - | - |
| NCT00177710 | Lung Transplantation ... more >> Fungal Infections Collapse << | Phase 3 | Completed | - | United States, Pennsylvania ... more >> University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00832208 | Visceral Leishmaniasis | Phase 2 | Terminated | - | Ethiopia ... more >> Arba Minch LRTC Arba Minch, Ethiopia Gondar Gondar, Ethiopia Sudan Kassab Hospital Kassab, Gedarif, Sudan Collapse << |
| NCT01566552 | Visceral Leishmaniasis | Phase 4 | Unknown | December 2017 | India ... more >> Kala Azar Medical Research Center Not yet recruiting Muzaffarpur, Bihar, India, 842001 Contact: DEEPAK VERMA, MBBS 916212287570 KMARCMFP@HOTMAIL.COM Collapse << |
| NCT00815516 | Candidiasis | Phase 3 | Terminated(It was decided to d... more >>iscontinue the study due to insufficient recruitment.) Collapse << | - | United States, California ... more >> Children's Hospital of Orange County Orange, California, United States, 92868 United States, New Jersey UMDNJ/Robert Wood Johnson Medical School New Brunswick, New Jersey, United States, 08901 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 WakeMed Health and Hospitals Raleigh, North Carolina, United States, 27610 United States, Virginia Virginia Commonwealth University Richmond, Virginia, United States, 23298 Brazil Irmandade da Santa Casa de Misericórdia de Belo Horizonte Belo Horizonte, Minas Gerais, Brazil, 30150-221 Hospital de Base da Faculdade de Medicina São José do Rio Preto, Sao Paulo, Brazil, 15090-000 Bulgaria Spec Hospital for Active Treatment of Children Diseases Sofia, Bulgaria, 1606 Canada, Ontario McMaster Children's Hospital Hamilton, Ontario, Canada, L8N 3Z5 Colombia Hospital Pablo Tobon Uribe Medellin, Antioque, Colombia, 574 Greece University Hospital of Patras Patras, Greece, 26504 Hungary Semmelweis Egyetem Budapest, Hungary, 8200 Israel Hadassah University Hospital Ein Kerem Jerusalem, Israel, 91120 Philippines Philippine General Hospital Manila, Philippines Romania Emergency County Clinical Hospital Cluj-Napoca, Romania, 400006 Turkey Cukurova University Medical Faculty Adana, Turkey, 1330 Ukraine Municipal Institution "Odesa Regional Children's Hospital" Odesa, Ukraine, 65031 Collapse << |
| NCT02686853 | Cryptococcal Meningitis | Phase 4 | Unknown | - | - |
| NCT00815516 | - | - | Terminated(It was decided to d... more >>iscontinue the study due to insufficient recruitment.) Collapse << | - | - |
| NCT00425620 | Chronic Sinusitis | Phase 3 | Completed | - | - |
| NCT01945281 | - | - | Terminated(Operational feasibi... more >>lity with low recruitment due to changing epidemiology of disease) Collapse << | - | - |
| NCT03311607 | Post-kala-azar Dermal Leishman... more >>iasis Collapse << | Phase 4 | Completed | - | - |
| NCT01259713 | Invasive Fungal Disease | Phase 3 | Completed | - | United Kingdom ... more >> Gilead Sciences Cambridge, United Kingdom, CB21 6GT Collapse << |
| NCT00177684 | Lung Transplantation ... more >> Fungal Infections Collapse << | Phase 3 | Completed | - | United States, Pennsylvania ... more >> University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00467883 | Zygomycosis | Phase 2 | Completed | - | France ... more >> Hôpital Necker - Service des Maladies Infectieuses et Tropicales Paris, France, 75015 Necker Hospital Paris, France, 75015 Collapse << |
| NCT02011958 | Visceral Leishmaniasis | Phase 3 | Unknown | April 2017 | Ethiopia ... more >> MSF Abdurafi, Ethiopia Leishmaniasis Research Center, University Hospital of Gondar Gondar, Ethiopia Collapse << |
| NCT01032187 | Visceral Leishmaniasis | Phase 4 | Completed | - | Brazil ... more >> Hospital de Doenças Tropicais Araguaína, Tocantins, Brazil Hospital Dona Regina Palmas, Tocantins, Brazil Collapse << |
| NCT01259713 | - | - | Completed | - | - |
| NCT00628719 | Visceral Leishmaniasis | Phase 3 | Completed | - | India ... more >> Kala-azar Medical Research Center, Rambag Road Muzaffarpur, India, 842001 Collapse << |
| NCT00371995 | Visceral Leishmaniasis | Phase 2 | Completed | - | India ... more >> Kala-azar Medical Research Center Muzaffarpur, Bihar, India, 842001 Rajendra Memorial Research Institute of Medical Sciences Patna, Bihar, India Collapse << |
| NCT02136030 | Cryptococcal Meningitis | Not Applicable | Unknown | December 2016 | Taiwan ... more >> National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 Collapse << |
| NCT01652859 | Normal Healthy Subjects | Phase 1 | Completed | - | - |
| NCT03196921 | Cryptococcal Infections | Phase 1 Phase 2 | Not yet recruiting | March 1, 2020 | - |
| NCT02629419 | Candidiasis, Chronic Mucocutan... more >>eous Collapse << | Phase 2 | Recruiting | December 2019 | United States, Maryland ... more >> National Institute of Allergy and Infectious Disease (NIAID) Recruiting Bethesda, Maryland, United States, 20892 Contact: Alexandra Freeman, MD freemaal@mail.nih.gov Principal Investigator: Alexandra Freeman, MD Sub-Investigator: Michail S. Lionakis, MD, ScD Collapse << |
| NCT01303549 | Liver Disease ... more >> Fungal Infection Collapse << | Phase 4 | Completed | - | Spain ... more >> Hospital Clinic i Provincial Barcelona, Spain Hospital de Bellvitge Barcelona, Spain Hospital Vall d'Hebrón Barcelona, Spain Hospital de Cruces Bilbao, Spain Hospital Reina Sofia Córdoba, Spain Complexo Hospitalario de A Coruña La Coruña, Spain Hospital Doce de Octubre Madrid, Spain Hospital Gregorio Marañón Madrid, Spain Hospital Ramón y Cajal Madrid, Spain Hospital Carlos Haya Malaga, Spain Hospital Central de Asturias Oviedo, Spain Hospital Marqués de Valdecilla Santander, Spain Collapse << |
| NCT00876824 | Leishmaniasis, Visceral | Phase 3 | Completed | - | India ... more >> Muzaffarpur, Bihar, India, 842001 Muzaffarpur, Bihar, India, 842003 Patna, Bihar, India, 800001 Patna, Bihar, India, 800007 Collapse << |
| NCT01845727 | Cutaneous Leishmaniasis | Phase 1 Phase 2 | Completed | - | Colombia ... more >> Programa de Estudios y Control de Enfermedades Tropicales (PECET), Universidad de Antioquia Medellin, Colombia Collapse << |
| NCT02025491 | Disseminated Leishmaniasis | Phase 3 | Completed | - | Brazil ... more >> HUPES Salvador, Bahia, Brazil, 40000 Collapse << |
| NCT02283905 | Blastomycosis | Phase 4 | Suspended(Manufacturer of amph... more >>otericin-B deoxycholate cannot supply at this time.) Collapse << | December 2018 | Canada, Manitoba ... more >> St. Boniface General Hospital Winnipeg, Manitoba, Canada, R2H 2A6 Collapse << |
| NCT02656797 | Leishmaniasis | Phase 2 | Recruiting | January 2021 | Israel ... more >> Soroka University Medical Center Recruiting Beer Sheva, Israel Contact: Amir Horev amirhor@clalit.org.il Collapse << |
| NCT01615809 | Invasive Pulmonary Aspergillos... more >>is Lymphoblastic Leukaemia Myeloblastic Leukaemia Lymphoblastic Leukemia Myeloblastic Leukemia Collapse << | Phase 2 | Completed | - | Spain ... more >> Hospital Sant Joan de Déu Esplugues de Llobregat, Barcelona, Spain, 08950 Collapse << |
| NCT01615809 | - | - | Completed | - | - |
| NCT02320604 | Morbid Obesity | Phase 4 | Completed | - | Netherlands ... more >> Radboud University Medical Center Nijmegen, Gelderland, Netherlands St. Antonius hospital Nieuwegein, Netherlands Collapse << |
| NCT03511820 | - | - | Completed | - | Taiwan ... more >> Changhua Christian Hospital Changhua, Taiwan, 500 Kaohsiung Veterans General Hospital Kaohsiung, Taiwan, 81362 Kaohsiung Chang Gung Memorial Hospital Kaohsiung, Taiwan, 833 Keelung Chang Gung Memorial Hospital Keelung, Taiwan, 204 China Medical University Hospital Taichung City, Taiwan, 40447 Tri-Service General Hospital Taipei city, Taiwan, 114 Taipei Veterans General Hospital Taipei, Taiwan, 11212 Taipei Mucinipal Wanfang Hospital Taipei, Taiwan, 116 Chang Guang Memorial Hospital at LinKou Taoyuan, Taiwan, 333 Collapse << |
| NCT03636659 | Visceral Leishmaniasis | Phase 1 | Recruiting | March 2019 | Bangladesh ... more >> International Centre for Diarrhoeal Disease Research b Not yet recruiting Dhaka, Bangladesh, 1212 Contact: Dr. Dinesh Mondal, MD 1712027091 din63d@icddrb.org Contact: Dr. Shomik Maruf, MBBS 1673587409 shomik.maruf@icddrb.org Principal Investigator: Dr. Dinesh Mondal, MD India Kala-Azar medical Research Centre Recruiting Muzaffarpur, Bihar, India, 842001 Contact: Dr. Shyam Sundar, MD 9453048500 drshyamsundar@hotmail.com Contact: Tauseeb Malik, B.Pharm 8299225413 tauseebmalik8574@gmail.com Principal Investigator: Dr. Shyam Sundar, MD Rajendra Memorial Research Institute of Medical Sciences Recruiting Patna, Bihar, India, 800007 Contact: Dr. Krishna Pandey, MD 9431042119 drkrishnapandey@yahoo.com Contact: Ms.Ranjeeta , Diploma 8553626714 ranjeetaraj96@gmail.com Principal Investigator: Dr. Krishna Pandey, MD Collapse << |
| NCT02660645 | - | - | Recruiting | December 2020 | United States, California ... more >> USC/Norris Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90033 Contact: Ileana Aldana 323-865-0702 ileana.aldana@med.usc.edu Principal Investigator: Sia Daneshmand, MD Sub-Investigator: Anne Schuckman, MD Sub-Investigator: Mihir Desai, MD Sub-Investigator: Hooman Djaladat, MD Sub-Investigator: Gerhard Fuchs, MD Sub-Investigator: Virinder Bhardwaj, MD VA Palo Alto Health Care System Recruiting Palo Alto, California, United States, 94304 Contact: Dorothy Trivedi dtrivedi@stanford.edu Principal Investigator: Joseph Liao, MD Sub-Investigator: James Crotty, MD Sub-Investigator: John Leppert, MD Sub-Investigator: John Lavelle, MD University of California, San Francisco Recruiting San Francisco, California, United States, 94143 Contact: Sima Porten, MD, MPH 415-885-3695 Sima.Porten@ucsf.edu Principal Investigator: Sima Porten, MD, MPH United States, Kansas University of Kansas Medical Center Recruiting Kansas City, Kansas, United States, 66160 Contact: Katie Glavin 913-588-8721 kglavin@kumc.edu Principal Investigator: John Taylor, MD, MS Sub-Investigator: Jeffrey Holzbeierlein, MD, FACS Sub-Investigator: Eugene Lee, MD, FACS Sub-Investigator: Hadley Wyre, MD Sub-Investigator: Moben Mirza, MD United States, Maryland Johns Hopkins Medicine Recruiting Baltimore, Maryland, United States, 21224 Contact: Morgan De Carli Mdecarl2@jhmi.edu Principal Investigator: Trinity Bivalacqua, MD, PhD Sub-Investigator: Phillip Pierorazio, MD United States, Minnesota University of Minnesota Recruiting Minneapolis, Minnesota, United States, 55455 Contact: Therese Perrier 612-625-3319 perri084@umn.edu Principal Investigator: Badrinath Konety, MD Sub-Investigator: Weight Chris, MD Sub-Investigator: Laureen Hemsley, MD United States, New York Stony Brook Urology Recruiting Stony Brook, New York, United States, 11794 Contact: Kim Lyktey Kim.Lyktey@stonybrookmedicine.edu Principal Investigator: John Fitzgerald, MD Sub-Investigator: Massimiliano Spaliviero, MD Sub-Investigator: Wayne Waltzer, MD United States, Ohio Cincinnati VA Medical Center Not yet recruiting Cincinnati, Ohio, United States, 45220 Contact: Krishnanath Gaitonde, MD Principal Investigator: Krishnanath Gaitonde, MD Ohio State University Wexner Medical Center Recruiting Columbus, Ohio, United States, 43210 Contact: Kamal Pohar, MD kamal.pohar@osumc.edu Principal Investigator: Kamal Pohar, MD Sub-Investigator: Megan Merrill, DO Sub-Investigator: Ahmad Shabsigh, MD Sub-Investigator: David Sharp, MD United States, South Carolina Carolina Urology Partners Recruiting West Columbia, South Carolina, United States, 29169 Contact: Nicol Brandon 704-414-2870 ext 2809 Nicol.brandon@carolinaurologypartners.com Principal Investigator: T. Brian Willard, MD Sub-Investigator: David Lamb, MD Sub-Investigator: Scott Sweazy, MD Sub-Investigator: Keith Birghtbill, MD Sub-Investigator: Michael Stotzer, MD United States, Texas UT Southwestern Not yet recruiting Dallas, Texas, United States, 75390 Contact: Yair Lotan, MD 214-645-8787 Principal Investigator: Yair Lotan, MD Sub-Investigator: Aditya Bagrodia, MD Sub-Investigator: Vitaly Margulis, MD Sub-Investigator: Ganesh Raj, MD, PhD Michael E. DeBakey VA Medical Center Recruiting Houston, Texas, United States, 77030 Contact: Ashley Jones, BS, CCRP 713-791-1414 ext 26694 Ashley.Jones2@bcm.edu Principal Investigator: Jennifer Taylor, MD, MPH Sub-Investigator: Jeffrey Jones, MD Sub-Investigator: Sidney Worsham, MD United States, West Virginia Charleston Area Medical Center Recruiting Charleston, West Virginia, United States, 25301 Contact: James Tierney, DO 304-388-9944 Principal Investigator: James Tierney, DO Sub-Investigator: Samuel Deem, DO Collapse << |
| NCT02439749 | Hypertension ... more >>Vascular Diseases Cardiovascular Diseases Collapse << | Not Applicable | Recruiting | December 2022 | - |
| NCT03500328 | Multiple Sclerosis, Relapsing-... more >>Remitting Collapse << | Not Applicable | Recruiting | October 31, 2022 | - |
| NCT00260559 | - | - | Recruiting | December 2050 | United States, Pennsylvania ... more >> University of Pittsburgh Medical Center - Heart, Lung, and Esophageal Surgical Institute Recruiting Pittsburgh, Pennsylvania, United States, 15213 Contact: Julie A. Ward, BSN 412-647-8583 wardj@upmc.edu Principal Investigator: James D. Luketich, MD Sub-Investigator: Neil A. Christie, MD Sub-Investigator: Arjun Pennathur, MD Sub-Investigator: Matthew Schuchert, MD Sub-Investigator: Manisha Shende, MD Sub-Investigator: Lawrence Crist, MD Sub-Investigator: Ryan Levy, MD Sub-Investigator: Omar Awais, DO Sub-Investigator: Katie Nason, MD Sub-Investigator: Kevin McGrath, MD Sub-Investigator: Angela Gallagher, CRNP Sub-Investigator: Jason Lamb, MD Sub-Investigator: Jonathan D'Cunha, MD Sub-Investigator: Rajeev Dhupar, MD Sub-Investigator: Inderpal Sarkaria, MD Sub-Investigator: Manuel Villa Sanchez, MD Sub-Investigator: Jadsada Athigakunagorn, MD Sub-Investigator: Nicholas Baker, MD UPMC - Hillman Cancer Center Recruiting Pittsburgh, Pennsylvania, United States, 15232 Contact: Julie A. Ward, BSN 412-647-8583 wardj@upmc.edu Collapse << |
