|(2R,3R,4R,5R)-2-(6-氨基-9H-嘌呤-9-基)-5-((((((((2R,3S,4R,5R)-5-(3-氨基甲酰吡啶-1-鎓-1-基)-3,4-二羟基四氢呋喃-2-基)甲氧基)氧化磷酰基)氧基)(羟基)磷酰基)氧基)甲基)-4-羟基四氢呋喃-3-基磷酸氢钠盐|CsnPharm

CAS No.: 1184-16-3

NADP钠盐 Catalog No. CSN10432

Synonyms: Sodium NADP

NADP sodium is a coenzyme that is widely distributed in living matter which participates in oxidation-reduction reactions.

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生物活性

实验方案

技术信息

生物活性

描述NADP sodium, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP sodium is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP+) and reduced (NADPH). NADP differs from NAD in only the presence of an additional phosphate group esterified to the 2'-hydroxyl group of the ribose at the adenine end and yet NADP is confined with few exceptions to the reactions of reductive biosynthesis, whereas NAD is used almost exclusively in oxidative degradations^[1]. NAD(P)-dependent enzymes generally share a common open alpha/beta fold with few exceptions only recently structurally characterized. The NH2-terminal mononucleotide binding domain is less variable than the COOH-terminal half, probably because it involves the binding of the ADP moiety of NAD(P) invariant in all examined systems^[2].
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01686204	Intestinal Barrier Function ... more >> Chronic Inflammation Collapse <<	Not Applicable	Completed	-	United States, Wisconsin ... more >> Department of Food Science, Babcock Hall Madison, Wisconsin, United States, 53706 Collapse <<

参考文献

[1] Carugo O, Argos P. NADP-dependent enzymes. I: Conserved stereochemistry of cofactor binding. Proteins. 1997 May;28(1):10-28
[2] Carugo O, Argos P. NADP-dependent enzymes. II: Evolution of the mono- and dinucleotide binding domains. Proteins. 1997 May;28(1):29-40

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.3065 mL
- 6.5326 mL
- 13.0653 mL
- 5 mM
- 0.2613 mL
- 1.3065 mL
- 2.6131 mL
- 10 mM
- 0.1307 mL
- 0.6533 mL
- 1.3065 mL

技术信息

CAS号

1184-16-3

储存条件

粉末: Inert atmosphere,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C21H27N7NaO17P3

运输

蓝冰

分子量

765.39

别名

Sodium NADP

溶解度

Water

150.0 mg/mL (196.0 mM) warming

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