CAS No.: 861393-28-4
A-740003 Catalog No. CSN13107
A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Janssen B, Vugts DJ, et al. Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [¹¹C] A-740003 as a novel tracer of neuroinflammation. J Labelled Comp Radiopharm. 2014 Jun 30;57(8):509-16.
- [2] Honore P, Donnelly-Roberts D, et al. A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide] , a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat. J Pharmacol Exp Ther. 2006 Dec;319(3):1376-85.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 861393-28-4 | 储存条件 |
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| 分子式 | C26H30N6O3 | 运输 | 蓝冰 | |
| 分子量 | 474.55 | 别名 |
