CAS No.: 909910-43-6
A 83-01 Catalog No. CSN13090
Synonyms: A 83-01
A 83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7, with IC50 values of 12, 45 and 7.5 nM, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Yamamura S, Matsumura N, et al. The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer. Int J Cancer. 2012 Jan 1;130(1):20-8.
- [2] Furutani Y, Umemoto T, et al. Role of endogenous TGF-β family in myogenic differentiation of C2C12 cells. J Cell Biochem. 2011 Feb;112(2):614-24.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 909910-43-6 | 储存条件 |
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| 分子式 | C25H19N5S | 运输 | 蓝冰 | |||||||||||||
| 分子量 | 421.52 | 别名 | A 83-01 | |||||||||||||
| 溶解度 |
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动物实验配方 |
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