CAS No.: 62218-13-7
α-Viniferin Catalog No. CSN14397
Synonyms: (+)-α-Viniferin
alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Sim J, Jang HW, et al. Potent inhibitory effect of alpha-viniferin on human cytochrome P450. Food Chem Toxicol. 2014 Jul;69:276-80.
- [2] Dilshara MG, Lee KT, et al. Anti-inflammatory mechanism of α-viniferin regulates lipopolysaccharide-induced release of proinflammatory mediators in BV2 microglial cells. Cell Immunol. 2014 Jul;290(1):21-9.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 62218-13-7 | 储存条件 |
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| 分子式 | C42H30O9 | 运输 | 蓝冰 | |
| 分子量 | 678.68 | 别名 | (+)-α-Viniferin |
