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CAS No.: 77337-73-6
Synonyms: Calcium N-acetylhomotaurinate;Acamprosate (calcium salt);N-acetyl Homotaurinate
Acamprosate calcium is an agonist of GABA receptor. It can act as a modulator of glutamatergic systems and reduce alcohol consumption in animal models of alcohol addiction.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02374567 | Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse << | Phase 3 | Terminated | - | Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse << |
NCT01437046 | Alcohol Dependence ... more >> Anxiety Collapse << | Phase 2 | Completed | - | United States, Rhode Island ... more >> Brown University Center for Alcohol and Addiction Studies Providence, Rhode Island, United States, 02903 Collapse << |
NCT01343628 | Alcohol-induced Cue-craving ... more >> Alcohol Sensitivity Collapse << | Phase 1 | Terminated(Terminated due to l... more >>ack of funding) Collapse << | - | United States, Virginia ... more >> Center for Addiction Research and Education Charlottesville/ Richmond, Virginia, United States, 22903 Collapse << |
实验方案
技术信息
CAS号 | 77337-73-6 | 储存条件 |
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分子式 | C10H20CaN2O8S2 | 运输 | 蓝冰 | |||||
分子量 | 400.48 | 别名 | Calcium N-acetylhomotaurinate;Acamprosate (calcium salt);N-acetyl Homotaurinate;N-acetyl Homotaurine;Alcomed;Aotal;Campral;Sobriol | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02374567 | Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse << | Phase 3 | Terminated | - | Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse << |
NCT01437046 | Alcohol Dependence ... more >> Anxiety Collapse << | Phase 2 | Completed | - | United States, Rhode Island ... more >> Brown University Center for Alcohol and Addiction Studies Providence, Rhode Island, United States, 02903 Collapse << |
NCT01343628 | Alcohol-induced Cue-craving ... more >> Alcohol Sensitivity Collapse << | Phase 1 | Terminated(Terminated due to l... more >>ack of funding) Collapse << | - | United States, Virginia ... more >> Center for Addiction Research and Education Charlottesville/ Richmond, Virginia, United States, 22903 Collapse << |
NCT02107352 | - | - | Completed | - | Belgium ... more >> CHU Brugmann Brussels, Belgium, 1020 Collapse << |
NCT02361242 | Alzheimer Disease | Phase 2 | Completed | - | France ... more >> CMRR Bordeaux, France Collapse << |
NCT02771925 | Alcohol Dependence | Phase 4 | Unknown | May 2018 | India ... more >> Dyanand Medical College and Hospital Recruiting Ludhiana, Punjab, India, 141001 Contact: Sandeep Singh Sidhu, MD,DM +919814025085 sandeepsidhu1963@gmail.com Contact: Omesh Goyal, MD,DM +919914821155 goyalomesh@yahoo.co.in Principal Investigator: Sandeep Singh Sidhu, MD,DM Collapse << |
NCT00120601 | Alcoholism | Phase 4 | Unknown | - | Australia, New South Wales ... more >> Drug Health Services, Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Collapse << |
NCT02217007 | Tourette Syndrome | Phase 2 | Completed | - | United States, Illinois ... more >> Rush University Medical Center Chicago, Illinois, United States, 60612 United States, New York North Shore University Hospital, Dept. of Psychiatry Manhasset, New York, United States, 11030 Collapse << |
NCT00590642 | - | - | Completed | - | United States, Nebraska ... more >> Creighton University Department of Psychiatry Omaha, Nebraska, United States, 68131 Collapse << |
NCT00317031 | Alcoholism | Phase 4 | Completed | - | Germany ... more >> Department of Psychiatry, University of Regensburg Regensburg, Bayern, Germany, 93053 Department of Psychiatry, University of Freiburg Freiburg, BW, Germany, 79104 Department of Psychiatry, University of Heidelberg Heidelberg, BW, Germany, 69115 Department of Addictive Behavior und Addiction Medicine, Central Institute of Mental Health Mannheim, BW, Germany, 68159 Department of Psychiatry, University of Tübingen Tuebingen, BW, Germany, 72076 Collapse << |
NCT00006206 | Alcoholism | Phase 3 | Completed | - | United States, Connecticut ... more >> Substance Abuse Treatment Unit, Yale University New Haven, Connecticut, United States, 06511 United States, Florida University of Miami School of Medicine Miami, Florida, United States, 33136 United States, Massachusetts Harvard University/McLean Hospital Belmont, Massachusetts, United States, 02478 Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Boston University School of Medicine Boston, Massachusetts, United States, 02118 United States, New Mexico Center on Alcoholism, Substance Abuse and Addiction, University of New Mexico Albuquerque, New Mexico, United States, 87106 United States, Pennsylvania Treatment and Research Center, University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Rhode Island Roger Williams Medical Center , Brown University Providence, Rhode Island, United States, 02908 United States, South Carolina Center for Alcohol Programs, Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, Texas Southwest Texas Addiction Research and Technology Center, University of Texas Health Science Center San Antonio, Texas, United States, 78229 United States, Washington Addictions Treatment Center, University of Washington Seattle, Washington, United States, 98108 United States, Wisconsin University of Wisconsin-Milwaukee Milwaukee, Wisconsin, United States, 53233 Collapse << |
NCT02064010 | Drug-induced Tardive Dyskinesi... more >>a Collapse << | Phase 2 | Completed | - | United States, California ... more >> UCLA - Greater Los Angeles Los Angeles, California, United States, 90073 Collapse << |
NCT02361424 | Alzheimer Disease | Phase 2 | Completed | - | France ... more >> CMRR Bordeaux, France Collapse << |
NCT00605904 | - | - | Completed | - | - |
NCT00435435 | Alcohol Dependence | Phase 4 | Completed | - | Finland ... more >> National Public Health Institute, Department of Mental Health and Alcohol Research Helsinki, Finland, 00251 Collapse << |
NCT00004552 | Alcoholism | Phase 2 | Completed | - | United States, Connecticut ... more >> Substance Abuse Treatment Unit, University of Connecticut New Haven, Connecticut, United States, 06511 Collapse << |
NCT00159107 | Alcoholism | Phase 4 | Completed | - | Germany ... more >> Department of Psychiatry and Psychotherapy at the Heinrich-Heine-University Düsseldorf, Rhineland State Clinics Düsseldorf, Bergische Landstraße 2, 40629 Düsseldorf, Germany Düsseldorf, North Rhine-Westfalia, Germany, 40629 Collapse << |
NCT00855699 | Alcoholism | Phase 4 | Completed | - | United Kingdom ... more >> University of Bristol, Bristol PCT. Bristol, United Kingdom, BS6 6JL Collapse << |
NCT00511940 | Binge Eating Disorder | Phase 2 Phase 3 | Completed | - | United States, Ohio ... more >> Lindner Center of HOPE Mason, Ohio, United States, 45040 Collapse << |
NCT00605904 | Alcoholism | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT02998151 | Fragile X Syndrome | Phase 2 | Enrolling by invitation | July 2021 | United States, Ohio ... more >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 Collapse << |
NCT00640952 | Parkinson's Disease | Not Applicable | Withdrawn(PI left site) | - | United States, Texas ... more >> PDCMDC 6550 Fannin, Suite 1801 Houston, Texas, United States, 77030 Collapse << |
NCT00452543 | Major Depressive Disorder ... more >> Alcohol Abuse Alcohol Dependence Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Collapse << |
NCT00330486 | Alcohol Dependence ... more >> Bipolar Disorder Collapse << | Phase 1 Phase 2 | Completed | - | United States, South Carolina ... more >> Institute of Psychiatry, Medical University of South Carolina Charleston, South Carolina, United States, 29425 Collapse << |
NCT00656630 | Alcoholism | Phase 2 | Completed | - | United States, California ... more >> The Scripps Research Institute La Jolla, California, United States, 92037 Collapse << |
NCT00452543 | - | - | Completed | - | - |
NCT00466661 | Alcohol Dependence ... more >> Bipolar Disorder Collapse << | Phase 4 | Completed | - | United States, South Carolina ... more >> Institute of Psychiatry, Medical University of South Carolina Charleston, South Carolina, United States, 29425 Collapse << |
NCT00656630 | - | - | Completed | - | - |
NCT00466661 | - | - | Completed | - | - |
NCT00330174 | Alcohol Dependence ... more >> Major Depression Social Anxiety Disorder Generalized Anxiety Disorder Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> McLean Hospital Belmont, Massachusetts, United States, 02478 United States, New York Columbia University College of Physicians & Surgeons New York, New York, United States, 10025 United States, South Carolina Behavioral Health Services of Pickens County Pickens, South Carolina, United States, 29671 Collapse << |
NCT00571922 | Methamphetamine Dependence, Tr... more >>eatment Seeking Collapse << | Phase 1 Phase 2 | Completed | - | United States, New York ... more >> VA New York Harbor Healthcare System, MHAD clinic New York, New York, United States, 10010 Collapse << |
NCT00330174 | - | - | Completed | - | - |
NCT00571922 | - | - | Completed | - | - |
NCT00360594 | Alcohol Use Disorder | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT00385268 | Cocaine Dependence | Phase 2 | Completed | - | United States, Pennsylvania ... more >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT03634917 | Alcoholism | Phase 3 | Not yet recruiting | April 30, 2020 | - |
NCT00385268 | - | - | Completed | - | - |
NCT00106106 | - | - | Completed | - | - |
NCT00106106 | Alcohol-Related Disorders ... more >> Alcohol Dependence Alcoholism Healthy Volunteer Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT00596531 | Tinnitus | Phase 1 | Completed | - | United States, Oregon ... more >> OHSU Portland, Oregon, United States, 97239 Collapse << |
NCT00591565 | Anxiety | Not Applicable | Completed | - | United States, New York ... more >> SUNY Upstate Medical University Psychiatry Dept. Syracuse, New York, United States, 13210 Collapse << |
NCT00655967 | Alcohol Dependence | Phase 4 | Unknown | December 2008 | United States, New Mexico ... more >> University of New Mexico Recruiting Albuquerque, New Mexico, United States, 87131-0001 Contact: Florian Birkmayer, M.D. 505-272-2223 fbirkmayer@salud.unm.edu Sub-Investigator: Michael Bogenschutz, M.D. Collapse << |
NCT01911455 | Fragile X Syndrome | Phase 2 Phase 3 | Recruiting | February 2018 | United States, Illinois ... more >> Rush University Medical Center Recruiting Chicago, Illinois, United States, 60612 Contact: Jamie Chin 312-942-0025 jamie_a_chin@rush.edu Principal Investigator: Elizabeth Berry-Kravis, MD United States, Ohio Cincinnati Children's Hospital Medical Center Recruiting Cincinnati, Ohio, United States, 45229 Contact: Katie Friedmann, RN 513-636-0523 fragilex@cchmc.org Principal Investigator: Craig Erickson, MD Collapse << |
NCT00591565 | - | - | Completed | - | - |
NCT00381043 | Alcohol Dependence | Phase 4 | Completed | - | United States, North Carolina ... more >> UNC Family Medicine Center Chapel Hill, North Carolina, United States, 27599 United States, Wisconsin Center for Addiction and Behavioral Health Research University of Wisconsin-Milwaukee Milwaukee, Wisconsin, United States, 53211 Collapse << |
NCT00381043 | - | - | Completed | - | - |
NCT00571103 | Pathological Gambling | Phase 4 | Completed | - | - |
NCT00688324 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 4 | Completed | - | United States, Maryland ... more >> VA Maryland Health Care System Baltimore, Maryland, United States, 21201 Keypoint Community Mental Health Centers- Dundalk Baltimore, Maryland, United States, 21222 Keypoint Community Mental Health Centers- Catonsville Baltimore, Maryland, United States, 21228 Maryland Psychiatric Research Center Baltimore, Maryland, United States, 21228 Collapse << |
NCT00249379 | - | - | Terminated(Not enough sugjects... more >> enrolled before funding ran out) Collapse << | - | - |
NCT00463346 | - | - | Completed | - | - |
NCT00463346 | Alcohol Dependence ... more >> Schizophrenia Collapse << | Phase 3 | Completed | - | United States, Connecticut ... more >> VA Connecticut Healthcare System WEst Haven, Connecticut, United States, 06516 Collapse << |
NCT00688324 | - | - | Completed | - | - |
NCT00249379 | Alcohol Dependence | Phase 4 | Terminated(Not enough sugjects... more >> enrolled before funding ran out) Collapse << | - | United States, Virginia ... more >> Virginia Commonwealth University Medical Center Richmond, Virginia, United States, 23219 Collapse << |
NCT00571103 | - | - | Completed | - | - |
NCT00425711 | Alcohol Dependence | Not Applicable | Terminated(Recruitment barrier... more >>s.) Collapse << | - | United States, Oklahoma ... more >> The University of Oklahoma, Tulsa Tulsa, Oklahoma, United States, 74135 Collapse << |
NCT01300923 | Fragile X Syndrome ... more >> Autism Spectrum Disorders Collapse << | Phase 3 | Completed | - | United States, Indiana ... more >> Riley Child and Adolescent Psychiatry Clinic - Riley Hospital for Children Indianapolis, Indiana, United States, 46202 Collapse << |
NCT01813318 | Autistic Disorder | Phase 2 Phase 3 | Recruiting | February 2018 | United States, Ohio ... more >> Cincinnati Children's Hospital Medical Center Recruiting Cincinnati, Ohio, United States, 45229 Principal Investigator: Craig A Erickson, MD Collapse << |
NCT01300923 | - | - | Completed | - | - |
NCT00662571 | - | - | Completed | - | United States, Minnesota ... more >> Mayo Clinic Rochester, Minnesota, United States, 55905 Collapse << |
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