|3,4',5-三乙酰氧基反式二苯烯|CsnPharm

CAS No.: 42206-94-0

Acetyl-trans-resveratrol/乙酰化白藜芦醇 Catalog No. CSN12331

Synonyms: Acetyl Resveratrol;Resveratrol triacetate;3,5,4'-Tri-O-acetylresveratrol

Triacetylresveratrol is a prodrug of resveratrol with multiple targets including sirt, COX, IKK β and LOX, etc..

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400-920-2911

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技术信息

生物活性

描述Triacetylresveratrol, a RES analog, as a potential chemoprevention agent by a gene expression-based. After treatment with 100 μM TRES for 48 h, the cell viability of PANC-1 cells was 90.66 ± 1.89%, and the cell viability of BxPC-3 cells was 56.94 ± 2.10%. TRES at the concentration of 50 μM could significantly induce apoptosis in PANC-1(56%) and BxPC-3 ( 88%)cells. TRES could also interrupt the interaction between STAT3 and NFκB,TRES may be function as inhibitors of NFκB:STAT3 interaction^[3].
参考文献

[1] Duan J, Yue W, et al. In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis, and STAT3 and NFκB signaling in pancreatic cancer cells. Sci Rep. 2016 Aug 19;6:31672.
[2] Sengupta R, Barone A, et al. Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions. Oncotarget. 2015 Jul 30;6(21):18282-92.
[3] Duan J, Yue W, E J, Malhotra J, Lu SE, Gu J, Xu F, Tan XL. In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis, and STAT3 and NFκB signaling in pancreatic cancer cells. Sci Rep. 2016 Aug 19;6:31672. doi: 10.1038/srep31672. PMID: 27539371; PMCID: PMC4990919.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.8220 mL
- 14.1102 mL
- 28.2204 mL
- 5 mM
- 0.5644 mL
- 2.8220 mL
- 5.6441 mL
- 10 mM
- 0.2822 mL
- 1.4110 mL
- 2.8220 mL

技术信息

CAS号

42206-94-0

储存条件

粉末: Keep in dark place,Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C20H18O6

运输

蓝冰

分子量

354.35

别名

Acetyl Resveratrol;Resveratrol triacetate;3,5,4'-Tri-O-acetylresveratrol;三乙酰基白藜芦醇;乙酰化白藜芦醇

溶解度

DMSO	120.0 mg/mL (338.6 mM) warming

动物实验配方

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Acetyl-trans-resveratrol/乙酰化白藜芦醇 Catalog No. CSN12331

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