|N-(2-(二异丙基氨基)乙基)-2-(2-羟基-4,5-二甲氧基苯甲酰胺)噻唑-4-甲酰胺|CsnPharm

CAS No.: 185106-16-5

Acotiamide Catalog No. CSN19809

Synonyms: Z-338 free base;YM443 free base;YM-443

Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.

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描述Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00323817	Functional Dyspepsia	Phase 2	Completed	-	Belgium ... more >> Leuven University Leuven, Belgium Collapse <<
NCT00333372	Functional Dyspepsia	Phase 2	Completed	-	Japan ... more >> Tohoku University Sendai, Japan Collapse <<
NCT00298194	Dyspepsia	Phase 2	Completed	-	Australia, South Australia ... more >> Royal Adelaide Hospital Adelaide, South Australia, Australia, 5000 Collapse <<

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参考文献

[1] Zai H, Matsueda K, et al. Effect of acotiamide on gastric emptying in healthy adult humans. Eur J Clin Invest. 2014 Dec;44(12):1215-21.
[2] Mayanagi S, Kishino M, et al. Efficacy of acotiamide in combination with esomeprazole for functional dyspepsia refractory to proton-pump inhibitor monotherapy. Tohoku J Exp Med. 2014;234(3):237-40.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.2195 mL
- 11.0975 mL
- 22.1950 mL
- 5 mM
- 0.4439 mL
- 2.2195 mL
- 4.4390 mL
- 10 mM
- 0.2220 mL
- 1.1098 mL
- 2.2195 mL

技术信息

CAS号	185106-16-5	储存条件	粉末 Sealed in dry,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C21H30N4O5S	运输	蓝冰
分子量	450.55	别名	Z-338 free base;YM443 free base;YM-443;Z-338

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT00323817	Functional Dyspepsia	Phase 2	Completed	-	Belgium ... more >> Leuven University Leuven, Belgium Collapse <<
NCT00333372	Functional Dyspepsia	Phase 2	Completed	-	Japan ... more >> Tohoku University Sendai, Japan Collapse <<
NCT00298194	Dyspepsia	Phase 2	Completed	-	Australia, South Australia ... more >> Royal Adelaide Hospital Adelaide, South Australia, Australia, 5000 Collapse <<
NCT00458328	Functioanl Dyspepsia	Phase 2	Completed	-	Japan ... more >> Kawasaki Medical School Kurashiki, Okayama, Japan, 701-0192 Collapse <<
NCT00850746	Functional Dyspepsia	Phase 1	Completed	-	United States, Washington ... more >> Tacoma, Washington, United States, 98418 Collapse <<
NCT00102310	Indigestion N... more >>ausea Collapse <<	Phase 2	Completed	-	-
NCT00764374	Dyspepsia Fun... more >>ctional Dyspepsia Collapse <<	Phase 3	Completed	-	Japan ... more >> Hokkaido, Japan Kansai, Japan Kantou, Japan Kyushu, Japan Collapse <<
NCT01973790	Dyspepsia	Phase 3	Completed	-	-
NCT00761358	Functional Dyspepsia	Phase 3	Completed	-	Japan ... more >> Hokkaido, Japan Tokyo, Japan Collapse <<
NCT03402984	Healthy	Not Applicable	Completed	-	Belgium ... more >> Jan Tack Leuven, Belgium, 3000 Collapse <<
NCT00920998	Healthy	Phase 1	Completed	-	Japan ... more >> Kyushu, Japan Collapse <<

Acotiamide Catalog No. CSN19809

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