CAS No.: 61276-17-3
Acteoside/类叶升麻苷 Catalog No. CSN11220
Synonyms: Acteoside;Kusaginin;TJC160
Acteoside, is a natural product isolated and purified from the herbs of Cistanche deserticola Y.C. Ma with known antioxidant activity. It is a protein kinase C inhibitor (IC50 =25 μM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
靶点 PKC
IC50:25μM- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03641248 Osteoarthritis, Knee Early Phase 1 Not yet recruiting June 2019 United States, Missouri ... more >> Univ of Missouri Health Care Center Not yet recruiting Columbia, Missouri, United States, 65211 Contact: Dean Hainsworth, MD 573-882-4894 ClinicalResearch@health.missouri.edu Collapse << NCT02662283 IGA Nephropathy Phase 2 Phase 3 Unknown November 2016 China, Guangdong ... more >> Department of Nephrology, 6th Affiliated Hospital, Sun Yat-Sen University Guangzhou, Guangdong, China, 510655 Collapse << - 参考文献
- [1] Santoro A, Bianco G, et al. Verminoside- and verbascoside-induced genotoxicity on human lymphocytes: involvement of PARP-1 and p53 proteins. Toxicol Lett. 2008 May 5;178(2):71-6.
- [2] Herbert JM, Maffrand JP, et al. Verbascoside isolated from Lantana camara, an inhibitor of protein kinase C. J Nat Prod. 1991 Nov-Dec;54(6):1595-600.
- [3] Herbert JM, Maffrand JP, Taoubi K, Augereau JM, Fouraste I, Gleye J. Verbascoside isolated from Lantana camara, an inhibitor of protein kinase C. J Nat Prod. 1991 Nov-Dec;54(6):1595-600
- [4] Ma D, Wang J, Liu L, Chen M, Wang Z. Acteoside as a potential therapeutic option for primary hepatocellular carcinoma: a preclinical study. BMC Cancer. 2020 Sep 29;20(1):936
- [5] Qiao Z, Tang J, Wu W, Tang J, Liu M. Acteoside inhibits inflammatory response via JAK/STAT signaling pathway in osteoarthritic rats. BMC Complement Altern Med. 2019 Oct 7;19(1):264
- [6] Gan L, Li X, Zhu M, Chen C, Luo H, Zhou Q. Acteoside relieves mesangial cell injury by regulating Th22 cell chemotaxis and proliferation in IgA nephropathy. Ren Fail. 2018 Nov;40(1):364-370
- [7] Li M, Zhou F, Xu T, Song H, Lu B. Acteoside protects against 6-OHDA-induced dopaminergic neuron damage via Nrf2-ARE signaling pathway. Food Chem Toxicol. 2018 Sep;119:6-13
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 61276-17-3 | 储存条件 |
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| 分子式 | C29H36O15 | 运输 | 蓝冰 | |||||
| 分子量 | 624.59 | 别名 | Acteoside;Kusaginin;TJC160;NSC 603831;Acetoside;麦角甾苷;毛蕊花糖苷 | |||||
| 溶解度 |
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动物实验配方 |
