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CAS No.: 2922-28-3

Adenine hydrochloride/腺嘌呤盐酸盐半水合物 Catalog No. CSN23390

Synonyms: 6-Aminopurine hydrochloride;Vitamin B4 hydrochloride;6-Aminopurine HCl

Adenine HCl is a purine derivative and a nucleobase with a variety of biochemistry roles.

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技术信息

生物活性

描述Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA, with the other three being cytosine (C), guanine (G), and thymine (T). Adenine plays an important role in biochemistry, including cellular respiration and protein synethesis^[1]. Cleave DNA preferentially at guanines, at adenines, at cytosines and thymines equally, and at cytosines alone. When the products of these four reactions are resolved by size, by electrophoresis on a polyacrylamide gel, the DNA sequence can be read from the pattern of radioactive bands^[2]. Purine formation requires tautomerization of 5 to the conjugated amidine 6 (via hydrogen-tunneling, thermally with H(+) -catalysis, or by photolysis) or to keteneimine 7 (by photolysis)^[3]. The adenine-uracil interaction, which involves two hydrogen bonds (rather than three, as in guanine-cytosine pairing) is weak and nonspecific. Pairing of adenine with many other partners has been observed with monomers, synthetic oligonucleotides and in RNA^[4]. In addition to DNA cytosine methylation (5-methyl-2'-deoxycytidine, m5dC), DNA adenine methylation (N6-methyl-2'-deoxyadenosine, m6dA) is another DNA modification that has been discovered in eukaryotes^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 5.8279 mL
- 29.1396 mL
- 58.2793 mL
- 5 mM
- 1.1656 mL
- 5.8279 mL
- 11.6559 mL
- 10 mM
- 0.5828 mL
- 2.9140 mL
- 5.8279 mL

技术信息

CAS号

2922-28-3

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C5H6ClN5

运输

蓝冰

分子量

171.59

别名

6-Aminopurine hydrochloride;Vitamin B4 hydrochloride;6-Aminopurine HCl;Vitamin B4 HCl;Leucon;腺嘌呤盐酸盐;盐酸腺嘌呤

溶解度

DMSO	8.0 mg/mL (46.6 mM)
Ethanol	Insoluble

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Adenine hydrochloride/腺嘌呤盐酸盐半水合物 Catalog No. CSN23390

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