CAS No.: 958295-17-5
AGN 196996 Catalog No. CSN17042
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM showing little binding affinity for RARβ (Ki=1087 nM) and RARγ (Ki=8523 nM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Keedwell RG, Zhao Y, et al. An antagonist of retinoic acid receptors more effectively inhibits growth of human prostate cancer cells than normal prostate epithelium. Br J Cancer. 2004 Aug 2;91(3):580-8.
- [2] Hammond LA, Van Krinks CH, Durham J, et al. Antagonists of retinoic acid receptors (RARs) are potent growth inhibitors of prostate carcinoma cells. Br J Cancer. 2001 Aug 3;85(3):453-62.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 958295-17-5 | 储存条件 |
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| 分子式 | C24H20BrNO5 | 运输 | 蓝冰 | |
| 分子量 | 482.32 | 别名 |
