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CAS No.: 51264-14-3
Synonyms: m-AMSA;acridinyl anisidide;AMSA
Amsacrine can intercalate into the DNA of tumor cells with antineoplastic activity.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00002658 | Leukemia Neut... more >>ropenia Collapse << | Phase 3 | Unknown | - | United Kingdom ... more >> University of Wales College of Medicine Cardiff, Wales, United Kingdom, CF14 4XN Collapse << |
NCT00002719 | Leukemia Neut... more >>ropenia Collapse << | Phase 3 | Completed | - | Italy ... more >> Azienda Policlinico Umberto Primo Rome, Italy, 00161 Collapse << |
NCT00840684 | Leukemia | Phase 1 Phase 2 | Completed | - | France ... more >> Marseille Institute of Cancer - Institut J. Paoli and I. Calmettes Marseille, France, 13273 Collapse << |
实验方案
技术信息
CAS号 | 51264-14-3 | 储存条件 |
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分子式 | C21H19N3O3S | 运输 | 蓝冰 | |||
分子量 | 393.46 | 别名 | m-AMSA;acridinyl anisidide;AMSA;CI-880;SN-11841;Amsidine;Amsidyl;安吖啶 | |||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00002658 | Leukemia Neut... more >>ropenia Collapse << | Phase 3 | Unknown | - | United Kingdom ... more >> University of Wales College of Medicine Cardiff, Wales, United Kingdom, CF14 4XN Collapse << |
NCT00002719 | Leukemia Neut... more >>ropenia Collapse << | Phase 3 | Completed | - | Italy ... more >> Azienda Policlinico Umberto Primo Rome, Italy, 00161 Collapse << |
NCT00840684 | Leukemia | Phase 1 Phase 2 | Completed | - | France ... more >> Marseille Institute of Cancer - Institut J. Paoli and I. Calmettes Marseille, France, 13273 Collapse << |
NCT00003436 | Leukemia Myel... more >>odysplastic Syndromes Collapse << | Phase 3 | Completed | - | United Kingdom ... more >> Christie Hospital N.H.S. Trust Manchester, England, United Kingdom, M20 4BX Collapse << |
NCT02182596 | Acute Myeloid Leukemia | Phase 1 Phase 2 | Completed | - | France ... more >> Hopital Avicenne Bobigny, France CH Caen, France, 14033 Hopital Percy Clamart, France, 92141 CHU Creteil, France, 94010 CHU Lille, France, 59037 CH Limoges, France, 87042 Hopital Edouard Herriot Lyon, France CH Meaux, France, 77104 St Antoine Hospital Paris, France, 75012 Hopital Saint-Louis Paris, France CH Roubaix, France, 59100 CHU Rouen, France, 76038 CNLCC Saint-Cloud, France CH Versailles, France IGR Villejuif, France, 94805 Collapse << |
NCT01039363 | Acute Myeloid Leukemia | Phase 2 | Unknown | - | Korea, Republic of ... more >> Samsung Medical Center Not yet recruiting Seoul, Korea, Republic of, 135-710 Principal Investigator: Dong Hwan Won, M.D.,Ph.D. Collapse << |
NCT00180102 | Leukemia, Nonlymphocytic, Acut... more >>e Collapse << | Phase 4 | Completed | - | Germany ... more >> Medical Department I, University Hospital Carl Gustav Carus Dresden, Germany, 01307 Collapse << |
NCT03765541 | Relapsed or Refractory Acute M... more >>yeloid Leukemia Collapse << | Phase 3 | Not yet recruiting | January 2024 | France ... more >> CHU de Grenoble Not yet recruiting Grenoble, France Contact: Jean-Yves CAHN, PhD CHU de Limoges Not yet recruiting Limoges, France Contact: Pascal TURLURE, MD Institut Paoli Calmettes Not yet recruiting Marseille, France Contact: Norbert VEY, PhD CHU de Montpellier Not yet recruiting Montpellier, France Contact: Hicheri Yosr, MD CHU de Nantes Not yet recruiting Nantes, France Contact: Pierre PETERLIN, MD CHU de Nîmes Not yet recruiting Nîmes, France Contact: Eric JOURDAN, MD CHU de Bordeaux Not yet recruiting Pessac, France Contact: Arnaud PIGNEUX, PhD CHU de Poitiers Not yet recruiting Poitiers, France Contact: Maria-Pilar GALLEGO-HERMANZ, MD Collapse << |
NCT01228331 | Leukemia | Phase 2 Phase 3 | Recruiting | September 2021 | Germany ... more >> Krankenanstalten Gilead gCmbH Neurochirurgische Klinik Recruiting Bielefeld, Germany, 33617 Contact: Contact Person 49-521-144-2728 Klinikum Bremen-Mitte Recruiting Bremen, Germany, D-28205 Contact: Contact Person 49-421-497-5413 Universitaetsklinikum Duesseldorf Recruiting Duesseldorf, Germany, D-40225 Contact: Contact Person 49-211-81-17662 Klinik und Poliklinik Fuer Kinder-und Jugendmedizin - Universitaetsklinikum Greifswald Recruiting Greifswald, Germany, 17487 Contact: Contact Person 49-3834-86-6321 University Medical Center Hamburg - Eppendorf Recruiting Hamburg, Germany, D-20246 Contact: Contact Person 49-407-4105-2580 horstmann@uke.uni-hamburg.de Clinic for Bone Marrow Transplantation and Hematology and Oncology Recruiting Idar-Oberstein, Germany, D-55743 Contact: Contact Person 49-6781-66-1582 Klinikum Krefeld GmbH Recruiting Krefeld, Germany, D-47805 Contact: Contact Person 49-2151-322-375 Universitaets - Kinderklinik Recruiting Leipzig, Germany, D-04317 Contact: Contact Person 49-341-9726-113 Johannes Gutenberg University Recruiting Mainz, Germany, D-55101 Contact: Contact Person 49-6131-17-2642 Dr. von Haunersches Kinderspital der Universitaet Muenchen Recruiting Munich, Germany, D-80337 Contact: Contact Person 49-89-5160-2843 Staedtisches Krankenhaus Muenchen - Harlaching Recruiting Munich, Germany, D-81545 Contact: Contact Person 49-89-6210-2720 Klinik St. Hedwig-Kinderklinik Recruiting Regensburg, Germany, 93049 Contact: Contact Person 49-941-2080-493 Dr. Horst-Schmidt-Kliniken Recruiting Wiesbaden, Germany, D-65199 Contact: Contact Person 49-611-43-2564 Helios Kliniken Wuppertal University Hospital Recruiting Wuppertal, Germany, D-42283 Contact: Contact Person 49-202-896-2444 Collapse << |
NCT01324063 | Leukemia | Phase 3 | Completed | - | - |
NCT01423175 | Acute Myeloid Leukemia ... more >> MDS Collapse << | Phase 2 | Unknown | - | Germany ... more >> Hannover Medical School Recruiting Hannover, Germany, 30625 Contact: Arnold Ganser, Prof. Dr. ++49-511-532-3020 ganser.arnold@mh-hannover.de Universitaetsklinikum des Saarlandes Not yet recruiting Homburg/Saar, Germany, 66421 Contact: Michael Pfreundschuh, Prof. Dr. ++49-6841-16-23002 pfreundschuh@unikliniksaarland.de Universitaetsklinikum Leipzig AoeR Not yet recruiting Leipzig, Germany, 04103 Contact: Dietger Niederwieser, Prof. Dr. ++49-341-0713050 dietger.niederwieser@medizin.uni-leipzig.de Collapse << |
靶点 | Description | IC50 |
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