CAS No.: 739366-20-2
Anagliptin/利格列汀 Catalog No. CSN16158
Synonyms: SK-0403;利格列汀
Anagliptin is a potent and selective DPP-4 inhibitor(IC50= 3.8 nM) and > 10 fold less potent for DPP-8 and DPP-9.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02312427 Heart Failure ... more >> Diabetes Mellitus Collapse << Phase 4 Completed - Japan ... more >> Mitsui Memorial Hospital Taito-ku, Tokyo, Japan Collapse << NCT02528019 Effects of the DPP-4 Inhibitor... more >>s or SGLT2 Inhibitors on the Protective Actions for Diabetic Complications Collapse << Phase 4 Unknown August 2018 Japan ... more >> Kurume University Hospital Recruiting Kurume city, Japan, 830-0011 Contact: Nobuhiro Tahara, MD, PhD +81-942-31-7580 ntahara@med.kurume-u.ac.jp Contact: Sho-ichi Yamagishi, MD, PhD +81-942-31-7562 Principal Investigator: Nobuhiro Tahara, MD, PhD Collapse << NCT01529528 Type 2 Diabetes Mellitus Phase 3 Completed - Korea, Republic of ... more >> Kangbuk Samsung Hospital Seoul, Korea, Republic of Collapse << - 更多
- 参考文献
- [1] Ervinna N, Mita T, et al. Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice. Endocrinology. 2013 Mar;154(3):1260-70.
- [2] Kato N, Oka M, et al. Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl] -2-oxoethyl}amino)-2-methylpropyl] -2-methyl pyrazolo[1,5-a] pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor. Bioorg Med Chem. 2011 Dec 1;19(23):7221-7.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 739366-20-2 | 储存条件 |
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| 分子式 | C19H25N7O2 | 运输 | 蓝冰 | |
| 分子量 | 383.45 | 别名 | SK-0403;利格列汀 |
