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CAS No.: 72432-10-1

Aniracetam/茴拉西坦 Catalog No. CSN10315

Synonyms: Ro 13-5057;Memodrin;Sarpul

Aniracetam is an allosteric modulator of AMPAR which can reduce glutamate receptor desensitization and potentiate metabotropic glutamate receptor activity.

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生物活性

实验方案

技术信息

生物活性

描述Aniracetam is another AMPAkine created by modifying the piracetam molecule by replacing the acetamide moiety with a 4-methoxybenzoyl group.aniracetam improved healthy rats' performance on active avoidance tasks, and on radial arm maze tasks ^[3]. Physiologically, aniracetam enhances both glutamatergic neurotransmission and long-term potentiation.But aniracetam does not alter behavior in normal healthy mice^[4].Further, aniracetam (a nootropic compound with glutamatergic activity and neuroprotective potential) is a promising option for patients with cognitive deficit of mild severity^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.5613 mL
- 22.8064 mL
- 45.6128 mL
- 5 mM
- 0.9123 mL
- 4.5613 mL
- 9.1226 mL
- 10 mM
- 0.4561 mL
- 2.2806 mL
- 4.5613 mL

技术信息

CAS号

72432-10-1

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C12H13NO3

运输

蓝冰

分子量

219.24

别名

Ro 13-5057;Memodrin;Sarpul;Ampamet;Draganon;茴拉西坦

溶解度

DMSO	100.0 mg/mL (456.1 mM) warming
Water	insoluble

动物实验配方

0.5% CMC-Na

80 mg/mL

clear

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