CAS No.: 66584-72-3
Ansamitocin P-3/安丝菌素P 3 Catalog No. CSN18377
Synonyms: Antibiotic C 15003P3;Maytansinol isobutyrate;Maytansinol Butyrate
Ansamitocin P-3, which is used as an antibody drug conjugate cytotoxin is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Venghateri JB, Gupta TK, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. PLoS One. 2013 Oct 4;8(10):e75182.
- [2] Liu Z, Floss HG, et al. An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics. J Pharm Biomed Anal. 2004 Nov 19;36(4):815-21.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 66584-72-3 | 储存条件 |
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| 分子式 | C32H43ClN2O9 | 运输 | 蓝冰 | |||||
| 分子量 | 635.14 | 别名 | Antibiotic C 15003P3;Maytansinol isobutyrate;Maytansinol Butyrate;C15003P3;NSC-292222;Maytansinoid AP-3;安丝菌素P 3;安舒霉素 P-3 | |||||
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动物实验配方 |
