CAS No.: 1177827-73-4
AP-III-a4 Catalog No. CSN16974
Synonyms: ENOblock
ENOblock is a small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 μM) and inhibit cancer cell metastasis in vivo.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Cho H, Um J, et al. ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes. Sci Rep. 2017 Mar 8;7:44186.
- [2] Satani N, Lin YH, et al. ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase. PLoS One. 2016 Dec 28;11(12):e0168739.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1177827-73-4 | 储存条件 |
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| 分子式 | C31H43FN8O3 | 运输 | 蓝冰 | |
| 分子量 | 594.72 | 别名 | ENOblock |
