CAS No.: 832714-46-2
APD668 Catalog No. CSN16029
Synonyms: JNJ28630368
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively..
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Bahirat UA, Shenoy RR, et al. APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice. Eur J Pharmacol. 2017 Apr 15;801:35-45.
- [2] Semple G, Ren A, et al. Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 832714-46-2 | 储存条件 |
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| 分子式 | C21H24FN5O5S | 运输 | 蓝冰 | |||||||
| 分子量 | 477.51 | 别名 | JNJ28630368 | |||||||
| 溶解度 |
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动物实验配方 |
