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CAS No.: 74863-84-6
Synonyms: MD-805;MCI-9038;Argipidine
Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00603824 | Heparin-Induced Thrombocytopen... more >>ia Collapse << | Phase 4 | Withdrawn(PI relocated) | - | - |
NCT01911624 | Staphylococcus Aureus Bacterae... more >>mia Collapse << | Phase 2 | Completed | - | Belgium ... more >> KUleuven/UZ Gasthuisberg Leuven, Belgium, 3000 Collapse << |
NCT00921856 | Coronary Vasospasm ... more >> Microvascular Angina Coronary Artery Disease Collapse << | Not Applicable | Recruiting | December 2019 | Germany ... more >> Robert Bosch Medical Center Recruiting Stuttgart, Germany, 70376 Contact: Peter Ong, MD +4971181016048 petereong@gmail.com Contact: Anastasios Athanasiadis, MD +4971181015444 Collapse << |
实验方案
技术信息
CAS号 | 74863-84-6 | 储存条件 |
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分子式 | C23H36N6O5S | 运输 | 蓝冰 | |
分子量 | 508.63 | 别名 | MD-805;MCI-9038;Argipidine;DK-7419;GN-1600;MMTQAP;MPQA;OM 805;Slonnon;阿加曲班 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00603824 | Heparin-Induced Thrombocytopen... more >>ia Collapse << | Phase 4 | Withdrawn(PI relocated) | - | - |
NCT01911624 | Staphylococcus Aureus Bacterae... more >>mia Collapse << | Phase 2 | Completed | - | Belgium ... more >> KUleuven/UZ Gasthuisberg Leuven, Belgium, 3000 Collapse << |
NCT00921856 | Coronary Vasospasm ... more >> Microvascular Angina Coronary Artery Disease Collapse << | Not Applicable | Recruiting | December 2019 | Germany ... more >> Robert Bosch Medical Center Recruiting Stuttgart, Germany, 70376 Contact: Peter Ong, MD +4971181016048 petereong@gmail.com Contact: Anastasios Athanasiadis, MD +4971181015444 Collapse << |
NCT01162824 | Endothelial Dysfunction ... more >> Atherosclerosis Inflammation Myocardial Ischemia Collapse << | Not Applicable | Unknown | December 2011 | United Kingdom ... more >> Department of Cardiology, St George's Healthcare NHS Trust Recruiting London, England, United Kingdom, SW17 0RE Contact: Peter E Ong, MD +44208725 ext 2628 pong@sgul.ac.uk Sub-Investigator: Peter E Ong, MD Collapse << |
NCT02935530 | Gynecologic Neoplasms ... more >> Venous Thromboembolism Low Molecular Weight Heparin Argatroban Collapse << | Phase 3 | Unknown | December 2017 | China, Hubei ... more >> Tongji Hospital Recruiting Wuhan, Hubei, China, 430000 Contact: Danhui Weng, M.D. 027-83663351 dhweng@tjh.tjmu.edu.cn Collapse << |
NCT03735979 | Acute Ischemic Stroke | Phase 3 | Not yet recruiting | April 2023 | United States, Ohio ... more >> University of Cincinnati Medical Center Not yet recruiting Cincinnati, Ohio, United States, 45267 Contact: Natalie Kreitzer, MD kreitzne@UCMAIL.UC.EDU Collapse << |
NCT01304238 | - | - | Completed | - | - |
NCT01304238 | - | - | Completed | - | - |
NCT00508924 | Coronary Artery Disease ... more >> Angina, Unstable Collapse << | Phase 2 | Completed | - | Belgium ... more >> Aalst, Belgium Germany Bad Nauheim, Germany Cologne, Germany Dachau, Germany Dueren, Germany Frankfurt, Germany Halle, Germany Mainz, Germany Collapse << |
NCT00153946 | Stroke | Phase 4 | Completed | - | Japan ... more >> EAST Study Office c/o National Cardiovascular Center Suita, Osaka, Japan, 565-8565 Collapse << |
NCT00035178 | Kidney Failure, Chronic ... more >> Renal Disease, End-Stage Collapse << | Phase 4 | Completed | - | United States, Illinois ... more >> University of Chicago, Section of Nephrology Chicago, Illinois, United States, 60637 United States, Minnesota DaVita Clinical Research Minneapolis, Minnesota, United States, 55404 Collapse << |
NCT00039858 | Thrombocytopenia ... more >> Thrombosis Collapse << | Phase 4 | Completed | - | United States, California ... more >> Mattel Children's Hospital at UCLA Los Angeles, California, United States, 90095 Children's Hospital of Orange County Orange, California, United States, 92868 United States, Illinois Rush University Medical Center Chicago, Illinois, United States, 60612 University of Chicago Children's Hospital Chicago, Illinois, United States, 60637 Children's Hospital of Illinois Peoria, Illinois, United States, 61614 United States, Kentucky Kosair Children's Hospital, University of Louisville Louisville, Kentucky, United States, 40202 United States, Massachusetts Children's Hospital of Boston Boston, Massachusetts, United States, 02115 United States, Michigan Michigan Congenital Heart Center Ann Arbor, Michigan, United States, 48109 United States, Ohio Rainbow Babies at Children's Hospital Cleveland, Ohio, United States, 44106 United States, Oregon Oregon Health & Science University Portland, Oregon, United States, 97201 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 United States, Utah Primary Children's Medical Center Salt Lake City, Utah, United States, 84113 United States, Washington Children's Hospital and Regional Medical Center Seattle, Washington, United States, 98105 Collapse << |
NCT00508924 | - | - | Completed | - | - |
NCT00798525 | Heparin Induced Thrombocytopen... more >>ia (HIT) Collapse << | Phase 4 | Terminated(Supply of Lepirudin... more >> ended on 01. April 2012, thus trial terminated on 31. March 2012) Collapse << | - | Germany ... more >> Universitätsklinikum Düsseldorf Klinik für Anästhesiologie Düsseldorf, Germany, 40225 Collapse << |
NCT00198588 | Heparin-Induced Thrombocytopen... more >>ia Collapse << | Phase 3 | Completed | - | Japan ... more >> National Hospital Organization Nagoya Medical Center Nagoya, Aichi, Japan, 4600001 Nagoya University Hospital Nagoya, Aichi, Japan, 4668560 Nagoya Daini Red Cross Hospital Nagoya, Aichi, Japan, 4668650 National Hospital Organization Hakodate National Hospital Hakodate, Hokkaido, Japan, 0418512 National Hospital Organization Hokkaido Cancer Center Sapporo, Hokkaido, Japan, 0030804 Kurume University Hospital Kurume, Hukuoka, Japan, 8300011 Kobe University Hospital Kobe, Hyogo, Japan, 6500017 Kobe City General Hospital Kobe, Hyogo, Japan, 6500046 Iwate Medical University Hospital Morioka, Iwate, Japan, 0208505 Tokai University Hospital Isehara, Kanagawa, Japan, 2591193 Mie University Hospital Tsu, Mie, Japan, 5148507 National Cardiovascular Center Suita, Osaka, Japan, 5658565 Sakakibara Memorial Hospital Fuchu, Tokyo, Japan, 1830003 National Hospital Organization Iwakuni Clinical Center Iwakuni, Yamaguchi, Japan, 7408510 Yamaguchi University Hospital Ube, Yamaguchi, Japan, 7558505 Kyoto Second Red Cross Hospital Kyoto, Japan, 6028026 Kyoto University Hospital Kyoto, Japan, 6068507 The University of Tokyo Hospital Tokyo, Japan, 1138655 National Hospital Organization Tokyo Medical Center Tokyo, Japan, 1528902 Keio University Hospital Tokyo, Japan, 1608582 Collapse << |
NCT00787332 | - | - | Terminated(Low enrollment) | - | - |
NCT00861692 | Heparin-induced Thrombocytopen... more >>ia Type II Collapse << | Phase 2 | Completed | - | France ... more >> Saint Etienne, France Collapse << |
NCT01246011 | - | - | Terminated(Enrollment was too ... more >>slow.) Collapse << | - | - |
NCT00787332 | Suspected Heparin-Induced Thro... more >>mbocytopenia Collapse << | Phase 4 | Terminated(Low enrollment) | - | - |
NCT00268762 | Ischemic Stroke | Phase 1 Phase 2 | Completed | - | United States, Alabama ... more >> University of Alabama-Birmingham Birmingham, Alabama, United States, 35249 United States, California Cedars-Sinai Medical Center Los Angeles, California, United States, 90048 United States, Louisiana Tulane University New Orleans, Louisiana, United States, 70112 United States, Texas University of Texas-Southwestern Dallas Dallas, Texas, United States, 75390 Memorial Hermann Hospital-Medical Center Houston, Texas, United States, 77030 Memorial Hermann Southwest Hospital Houston, Texas, United States, 77074 Collapse << |
NCT00268762 | - | - | Completed | - | - |
NCT01246011 | Coronary Artery Bypass Graft S... more >>urgery Presence of Heparin/Platelet Factor 4 Antibody Collapse << | Phase 4 | Terminated(Enrollment was too ... more >>slow.) Collapse << | - | United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02474 Collapse << |
NCT01163604 | CVD | Phase 4 | Completed | - | China, Jiangsu ... more >> Department of Neurology, Jinling Hospital, Nanjing University School of Medicine Nanjing, Jiangsu, China, 210002 Collapse << |
NCT01464788 | - | - | Terminated(The study was halte... more >>d prematurely at 90 of 105 planned patients due to the beneficial results of embolectomy clinical trials.) Collapse << | - | - |
NCT01734252 | Achievement of a Sufficient Th... more >>rombosis Prohpylaxis in Clitically Ill Patients With Heparin Resistance Collapse << | Phase 2 | Completed | - | Austria ... more >> Medical University Innsbruck / Department for General and Surgical Intensive Care Medicine Innsbruck, Austria, 6020 Collapse << |
NCT03552354 | Stroke, Ischemic | Phase 4 | Recruiting | January 8, 2019 | China, Liaoning ... more >> General Hospital of Shenyang Military Region Recruiting Shenyang, Liaoning, China, 10016 Contact: Hui-sheng Chen, Doctor Collapse << |
NCT00861692 | - | - | Completed | - | - |
NCT01464788 | Ischemic Stroke | Phase 2 | Terminated(The study was halte... more >>d prematurely at 90 of 105 planned patients due to the beneficial results of embolectomy clinical trials.) Collapse << | - | United States, Texas ... more >> University of Texas Health Science Center at Houston Houston, Texas, United States, 77030 Collapse << |
NCT02448069 | Stroke Cerebr... more >>al Ischemia Collapse << | Phase 2 | Completed | - | United States, Texas ... more >> University of Texas Health Science Center at Houston Houston, Texas, United States, 77030 Collapse << |
NCT01163604 | - | - | Completed | - | - |
NCT03740958 | Stroke | Phase 4 | Not yet recruiting | June 30, 2021 | - |
NCT01980316 | CVD | Phase 4 | Completed | - | China, Jiangsu ... more >> Department of Neurology, Jinling Hospital, Nanjing University School of Medicine Nanjing, Jiangsu, China, 210009 Collapse << |
NCT03506009 | Argatroban, Rt-PA | Phase 4 | Terminated(it is very difficul... more >>t to recruit qualified patients) Collapse << | - | China, Liaoning ... more >> General Hospital of Shenyang Military Region Shenyang, Liaoning, China, 10016 Collapse << |
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