生物活性

• 描述Arginase inhibitor 1 is a potent small molecule inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT01195818	Sickle Cell Disease	Not Applicable	Completed	-	France ... more >> Centre de la Drépanocytose, Service de Médecine Interne. Hôpital Tenon, 4 Rue de la Chine Paris, France, 75020 Collapse <<
  NCT03314935	Biliary Tract Cancer (BTC) ... more >> Colorectal Cancer (CRC) Endometrial Cancer Gastroesophageal Cancer (GC) Ovarian Cancer Solid Tumors Collapse <<	Phase 1 Phase 2	Recruiting	May 27, 2020	United States, Alabama ... more >> University of Alabama Not yet recruiting Birmingham, Alabama, United States, 35294-3300 USA Mitchell Cancer Center Recruiting Mobile, Alabama, United States, 36604 United States, California UC Davis - Comprehensive Cancer Centre Not yet recruiting Sacramento, California, United States, 95817 United States, Georgia Northwest Georgia Oncology Centers Recruiting Marietta, Georgia, United States, 30060 United States, Texas The University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 START San Antonio Recruiting San Antonio, Texas, United States, 78229 Belgium Grand Hopital de Charleroi - Department of Medical Oncology Not yet recruiting Brussels, Belgium, 6000 Institut Jules Bordet - Clinical Trials Conduct Unit Recruiting Brussels, Belgium, B-1000 United Kingdom University of Liverpool Not yet recruiting Liverpool, United Kingdom, L69 3BX UCL Cancer Institute Recruiting London, United Kingdom, WC1E 6BT The Christie NHS Foundation Trust Recruiting Manchester, United Kingdom, M20 4BX Collapse <<
  NCT02903914	Metastatic Cancer ... more >> Solid Tumors Colorectal Cancer (CRC) Gastric Cancer Head and Neck Cancer Lung Cancer Renal Cell Carcinoma (RCC) Bladder Cancer UC (Urothelial Cancer) Mesothelioma Collapse <<	Phase 1 Phase 2	Recruiting	January 2020	United States, Alabama ... more >> University of South Alabama Recruiting Mobile, Alabama, United States, 36604 United States, Arizona Honor Health/Pinnacle Oncology Hematology Recruiting Scottsdale, Arizona, United States, 85258 Contact: Stephanie Althoff          Principal Investigator: Frank Tsai, MD          University of Arizona Recruiting Tucson, Arizona, United States, 85719 United States, District of Columbia Georgetown Recruiting Washington, District of Columbia, United States, 20007 United States, Maryland Johns Hopkins Recruiting Baltimore, Maryland, United States, 21287 United States, Massachusetts BIDMC Not yet recruiting Boston, Massachusetts, United States, 02215 DFCI Not yet recruiting Boston, Massachusetts, United States, 02215 United States, Michigan Henry Ford Recruiting Detroit, Michigan, United States, 48202 United States, Tennessee Sarah Cannon Research Institute at Tennessee Oncology Recruiting Nashville, Tennessee, United States, 37203 Contact: Erin Fisher          Principal Investigator: Todd Bauer, MD          Vanderbilt Recruiting Nashville, Tennessee, United States, 37232 United States, Texas MD Anderson Recruiting Houston, Texas, United States, 77230-1402 Contact: Yan Zhang, MD, PhD          Principal Investigator: Aung Naing, MD          MD Anderson Recruiting Houston, Texas, United States, 77230 START Recruiting San Antonio, Texas, United States, 78229 Contact: Edwin Blanco-Cepeda, RN Collapse <<

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