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CAS No.: 65576-45-6
Synonyms: Org 5222;HSDB-8061;trade names Saphris and Sycrest
Asenapine inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor(1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02181803 | Schizophrenia | Phase 1 | Completed | - | - |
NCT03565068 | Schizophrenia | Phase 1 | Suspended(Study is on hold pen... more >>ding evaluation of emerging preclinical findings) Collapse << | October 9, 2019 | United States, California ... more >> California Clinical Trials ( Site 0001) Glendale, California, United States, 91206 Collapse << |
NCT02600741 | - | - | Completed | - | - |
实验方案
技术信息
CAS号 | 65576-45-6 | 储存条件 |
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分子式 | C17H16ClNO | 运输 | 蓝冰 | |
分子量 | 285.77 | 别名 | Org 5222;HSDB-8061;trade names Saphris and Sycrest;阿塞那平 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02181803 | Schizophrenia | Phase 1 | Completed | - | - |
NCT03565068 | Schizophrenia | Phase 1 | Suspended(Study is on hold pen... more >>ding evaluation of emerging preclinical findings) Collapse << | October 9, 2019 | United States, California ... more >> California Clinical Trials ( Site 0001) Glendale, California, United States, 91206 Collapse << |
NCT02600741 | - | - | Completed | - | - |
NCT02213887 | Psychotic Disorders ... more >> Gastroesophageal Reflux Collapse << | Phase 4 | Active, not recruiting | August 2018 | Canada, British Columbia ... more >> UBC Hospital - Detwiller Pavilion Vancouver, British Columbia, Canada, V6T 2A1 Collapse << |
NCT01765829 | Psychosis Nos/Other | Phase 3 | Unknown | November 2015 | Spain ... more >> Mental Health Unit Villamartín Recruiting Villamartín, Cádiz, Spain, 11650 Contact: José María Mongil San Juan, MD 0034956040209 cheman45@gmail.com Principal Investigator: José María Mongil San Juan, MD Mental Health Unit Baza Recruiting Baza, Granada, Spain, 18800 Contact: Eva Bravo Barba, MD eva.bravo.barba@gmail.com Principal Investigator: Eva Bravo Barba, MD Mental Health Unit Motril Recruiting Motril, Granada, Spain, 18600 Contact: María Luisa Barrigón Estévez, MD 0034958038849 marial.barrigon.sspa@juntadeandalucia.es Principal Investigator: María Luisa Barrigón Estévez, MD Mental Health Unit Andújar Recruiting Andújar, Jaén, Spain, 23740 Contact: Fernando Sarramea Crespo, MD, PhD 0034953021717 fernandosarramea@hotmail.com Principal Investigator: Farnando Sarramea Crespo, MD, PhD Mental Health Unit Martos Recruiting Martos, Jaén, Spain, 23600 Contact: Miguel Ortigosa Luque, MD migueortigosa@hotmail.com Principal Investigator: Miguel Ortigosa Luque, MD Mental Health Unit Miraflores Not yet recruiting Alcobendas, Madrid, Spain, 28100 Contact: María Luisa Zamarro Arraz, MD, PhD 0034916530108 zamarroluisa@yahoo.es Principal Investigator: María Luisa Zamarro Arraz, MD, PhD Hospital Infanta Sofía Not yet recruiting San Sebastian de los Reyes, Madrid, Spain, 28702 Contact: María Rosario Gutiérrez Labrador, MD rosagutierrez@psiquiatra.e.telefonica.net Principal Investigator: María Rosario Guitiérrez Labrador, MD Mental Health Unit Valle del Guadalhorce Not yet recruiting Cártama, Málaga, Spain, 29580 Contact: Daniel Gutiérrez Castillo, MD 0034951033931 dgutierrezcastillo@gmail.com Principal Investigator: Daniel Gutiérrez Castillo, MD Mental Health Unit Las Lagunas Not yet recruiting Fuengiróla, Málaga, Spain, 29650 Contact: María Isabel Osuna Carmona, MD maribelosunac@hotmail.com Principal Investigator: María Isabel Osuna Carmona, MD Fundación Argibide Not yet recruiting Pamplona, Navarra, Spain, 31007 Contact: Ignacio Mata Pastor, MD, PhD 0034948266650 nacho.mata70@gmail.com Principal Investigator: Ignacio Mata Pastor, MD, PhD Hospital El Tomillar Recruiting Dos Hermanas, Seville, Spain, 41700 Contact: Joaquín Carlos Martín Muñoz, MD, PhD 0034955016083 joaquinmartin@hotmail.com Principal Investigator: Joaquín Carlos Martín Muñoz, MD, PhD Hospital Francesc de Borja Recruiting Gandía, Valencia, Spain, 46700 Contact: María Lacruz Silvestre, MD, PhD maria.lacruz.silvestre@gmail.com Principal Investigator: María Lacruz Silvestre, MD, PhD Hospital de Basurto Not yet recruiting Bilbao, Spain, 48013 Contact: Sonia Bustamante Madariaga, MD, Phd 0034944 006137 sonia.bustamantemadariaga@osakidetza.net Principal Investigator: Sonia Bustamante Madariaga, MD, PhD Mental Health Unit Tetuán Not yet recruiting Madrid, Spain, 28003 Contact: Mariano Hernández Monsalve, MD, PhD 0034915347363 hergoico@gmail.com Contact: Ruth Berdún Pe, MD ruthberdun@yahoo.es Principal Investigator: Mariano Hernández Monsalve, MD, PhD Lafora Hospital Not yet recruiting Madrid, Spain, 28049 Contact: Juan Dios Molina Martín, MD, PhD jmolinamar@hotmail.com Principal Investigator: Juan Dios Molina Martín, MD, PhD Hospital Carlos Haya Recruiting Málaga, Spain, 29009 Contact: Fermín Mayoral Cleríes, Md, PhD fermin.mayoral.sspa@juntadeandalucia.es Principal Investigator: Fermín Mayoral Cleríes, MD, PhD Virgen del Rocío Hospital Recruiting Seville, Spain, 41013 Contact: Clara M. Rosso Fernández, MD 0034955013414 claram.rosso.sspa@juntadeandalucia.es Contact: Miguel Ruiz Veguilla, MD, PhD 0034955013414 mruizveguilla@yahoo.com Principal Investigator: Miguel Ruiz Veguilla, MD, PhD Collapse << |
NCT00806234 | Psychotic Disorders | Phase 4 | Completed | - | United States, Maryland ... more >> University of Maryland Baltimore, Maryland, United States, 21201 Johns Hopkins Hospital Baltimore, Maryland, United States, 21205 United States, New York The Zucker Hillside Hospital Glen Oaks, New York, United States, 11004 United States, North Carolina University of North Carolina, Division of Child and Adolescent Psychiatry Chapel Hill, North Carolina, United States, 27599 Collapse << |
NCT02876900 | Schizophrenia | Phase 3 | Completed | - | United States, New York ... more >> Noven Pharmaceuticals, Inc. New York, New York, United States, 10118 Collapse << |
NCT00806234 | - | - | Completed | - | - |
NCT00156104 | Schizophrenia | Phase 3 | Completed | - | - |
NCT02893371 | - | - | Enrolling by invitation | June 2019 | United States, New Mexico ... more >> Christophe G Lambert Albuquerque, New Mexico, United States, 87131 Collapse << |
NCT00156117 | Schizophrenia | Phase 3 | Completed | - | - |
NCT01498770 | - | - | Completed | - | - |
NCT00265343 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00145496 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00145496 | - | - | Completed | - | - |
NCT00265343 | - | - | Completed | - | - |
NCT00212836 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00174265 | - | - | Completed | - | - |
NCT02072954 | Schizophrenia | Phase 2 Phase 3 | Completed | - | India ... more >> Shri Hatkesh Healthcare Foundation Junagadh, Gujurat, India, 362 001 Divyam Hospital Surat, Gujurat, India, 395 001 Collapse << |
NCT00156091 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00156065 | - | - | Completed | - | - |
NCT00212784 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 3 | Completed | - | - |
NCT00151424 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00212771 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 3 | Completed | - | - |
NCT00156065 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00174265 | Schizophrenia | Phase 3 | Completed | - | - |
NCT01617200 | Schizophrenia | Phase 3 | Completed | - | United States, Texas ... more >> Forest Investigative Site 2001 Austin, Texas, United States, 78754 Collapse << |
NCT00878462 | Psychosis | Phase 2 | Completed | - | - |
NCT01617187 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00159796 | Bipolar Disorder | Phase 3 | Completed | - | - |
NCT00150176 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00150176 | - | - | Completed | - | - |
NCT01098110 | Schizophrenia | Phase 3 | Completed | - | - |
NCT01495741 | - | - | Completed | - | - |
NCT01765127 | - | - | Completed | - | United Kingdom ... more >> Drug Safety Research Unit (for data collation and analysis only) Southampton, Hampshire, United Kingdom, SO31 1AA Collapse << |
NCT01734278 | - | - | Completed | - | United Kingdom ... more >> South Staffordshire and Shropshire Healthcare NHS Foundation Trust Stafford, Staffordshire, United Kingdom, ST16 3SR Collapse << |
NCT01617187 | - | - | Completed | - | - |
NCT00159744 | Bipolar Disorder | Phase 3 | Completed | - | - |
NCT00145470 | Bipolar Disorder | Phase 3 | Completed | - | - |
NCT00159783 | Bipolar Disorder | Phase 3 | Completed | - | - |
NCT00145509 | Bipolar Disorder | Phase 3 | Completed | - | - |
NCT01948024 | Schizophrenia ... more >> Bipolar Disorder Collapse << | Phase 1 | Completed | - | United States, Arkansas ... more >> Woodland International Research Group, Inc. Little Rock, Arkansas, United States, 72211 United States, California Clinical Innovations, Inc Costa Mesa, California, United States, 92280 Collaborative Neuroscience Network, LLC Garden Grove, California, United States, 92845 United States, Florida Compass Research North, LLC Leesburg, Florida, United States, 34748 Advanced Pharma CR, LLC Miami, Florida, United States, 33136 United States, Georgia Atlanta Center for Medical Research Atlanta, Georgia, United States, 30308 United States, North Carolina New Hope Clinical Research Charlotte, North Carolina, United States, 28204 Collapse << |
NCT01098110 | - | - | Completed | - | - |
NCT00159783 | - | - | Completed | - | - |
NCT01142596 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00145509 | - | - | Completed | - | - |
NCT01244828 | Schizophrenia | Phase 3 | Completed | - | - |
NCT01142596 | - | - | Completed | - | - |
NCT01244828 | - | - | Completed | - | - |
NCT00143182 | Bipolar Disorder | Phase 3 | Completed | - | - |
NCT00281320 | Psychosis | Phase 3 | Completed | - | - |
NCT00764478 | Bipolar 1 Disorder | Phase 3 | Completed | - | - |
NCT01244815 | Bipolar Disorder, Pediatric | Phase 3 | Completed | - | - |
NCT00281320 | - | - | Completed | - | - |
NCT00764478 | - | - | Completed | - | - |
NCT01670019 | Major Depressive Disorder With... more >>out Psychotic Features Collapse << | Phase 4 | Completed | - | United States, Georgia ... more >> Georgia Health Sciences University Augusta, Georgia, United States, 30912 United States, North Carolina Carolina Behavioral Care Durham, North Carolina, United States, 27704 Duke University Medical Center Durham, North Carolina, United States, 27710 Brody School of Medicine at East Carolina University Greenville, North Carolina, United States, 27834 North Carolina Psychiatric Research Center Raleigh, North Carolina, United States, 27603 Collapse << |
NCT01206517 | - | - | Completed | - | - |
NCT01206517 | Schizophrenia ... more >> Bipolar I Disorder Collapse << | Phase 1 | Completed | - | - |
NCT01101464 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 2 | Completed | - | - |
NCT01244815 | - | - | Completed | - | - |
NCT01670019 | - | - | Completed | - | - |
NCT01101464 | - | - | Completed | - | - |
NCT01400113 | Agitation | Phase 4 | Completed | - | United States, New York ... more >> St. Joseph's Hospital Health Center-Comprehensive Psychiatric Emergency Program (CPEP) Syracuse, New York, United States, 13203 Collapse << |
NCT01400113 | - | - | Completed | - | - |
NCT01190254 | - | - | Completed | - | - |
NCT01396291 | Bipolar 1 Disorder | Phase 3 | Completed | - | - |
NCT01349907 | - | - | Completed | - | - |
NCT01190254 | Schizophrenia, Paranoid ... more >> Schizophrenia, Disorganized Schizophrenia, Undifferentiated Collapse << | Phase 3 | Completed | - | - |
NCT01395992 | Bipolar I Disorder | Phase 3 | Completed | - | United States, Texas ... more >> Forest Investigative Site 1000 Austin, Texas, United States, 78754 Collapse << |
NCT01684657 | Stuttering | Phase 3 | Suspended(Study transferring t... more >>o another facility) Collapse << | May 2014 | United States, California ... more >> University of California Irvine Medical Center Orange, California, United States, 92868 Collapse << |
NCT01349907 | Bipolar Disorder | Phase 3 | Completed | - | - |
NCT01549041 | Schizophrenia | Phase 4 | Completed | - | United States, North Carolina ... more >> Central Regional Hospital Butner, North Carolina, United States, 27609 Collapse << |
NCT01190267 | - | - | Completed | - | - |
NCT01807741 | Bipolar Depression | Phase 2 | Terminated(funding ended due t... more >>o recruitment delays) Collapse << | - | United States, Ohio ... more >> University of Cincinnati Cincinnati, Ohio, United States, 45244 Collapse << |
NCT01460290 | Bipolar Disorder | Phase 4 | Completed | - | United States, Ohio ... more >> University Hospitals Case Medical Center Cleveland, Ohio, United States, 44106 Collapse << |
NCT01460290 | - | - | Completed | - | - |
NCT01190267 | Schizophrenia, Paranoid ... more >> Schizophrenia, Disorganized Schizophrenia, Undifferentiated Collapse << | Phase 3 | Completed | - | - |
NCT01587118 | - | - | Completed | - | - |
NCT01968161 | Schizophrenia and Disorders Wi... more >>th Psychotic Features Disorders Collapse << | Phase 4 | Unknown | March 2014 | Canada ... more >> Clinique Notre-Dame des Victoires Recruiting Quebec, Canada, G1K 4B2 Contact: Diana Pasat, BSc 418-694-2223 diana.pasat@yahoo.ca Principal Investigator: Marc-Andre Roy, MD Collapse << |
NCT01587118 | Posttraumatic Stress Disorder | Phase 4 | Completed | - | United States, Alabama ... more >> Tuscaloosa VA Medical Center Tuscaloosa, Alabama, United States, 35404 Collapse << |
NCT01549041 | - | - | Completed | - | - |
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