CAS No.: 104075-48-1
Atipamezole HCl/阿替美唑盐酸盐 Catalog No. CSN17267
Synonyms: MPV-1248 hydrochloride;Antisedan HCl;MPV-1248 HCl
Atipamezole HCl is a competitive α2-adrenergic receptor antagonist, mainly used in veterinary medicine.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01435213 Healthy Phase 1 Completed - Finland ... more >> University of Turku, Clinical Research Services Turku CRST Turku, Finland, 20520 University of Turku, Turku PET Centre Turku, Finland, 20520 Collapse << - 参考文献
- [1] Pertovaara A, Haapalinna A, et al. Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist. CNS Drug Rev. 2005 Autumn;11(3):273-88.
- [2] Sirvio J, Riekkinen P Jr, et al. The effects of alpha-2 adrenoceptor antagonist, atipamezole, on spatial learning in scopolamine-treated and aged rats. J Neural Transm Park Dis Dement Sect. 1992;4(2):99-106.
- [3] Pertovaara A, Haapalinna A, Sirviö J, Virtanen R. Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist. CNS Drug Rev. 2005 Autumn;11(3):273-88. doi: 10.1111/j.1527-3458.2005.tb00047.x. PMID: 16389294; PMCID: PMC6741735.
- [4] Izer JM, Whitcomb TL, Wilson RP. Atipamezole reverses ketamine-dexmedetomidine anesthesia without altering the antinociceptive effects of butorphanol and buprenorphine in female C57BL/6J mice. J Am Assoc Lab Anim Sci. 2014 Nov;53(6):675-83. PMID: 25650975; PMCID: PMC4253582.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 104075-48-1 | 储存条件 |
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| 分子式 | C14H17ClN2 | 运输 | 蓝冰 | |||||
| 分子量 | 248.75 | 别名 | MPV-1248 hydrochloride;Antisedan HCl;MPV-1248 HCl;Atipamezole (hydrochloride);Atipamezole;阿替美唑盐酸盐 | |||||
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动物实验配方 |
