CAS No.: 160800-57-7
Auristatin E/澳瑞他汀 E Catalog No. CSN17946
Synonyms: 澳瑞他汀 E;奥利斯他汀 E
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity and it is an MMAE analog and cytotoxin in Antibody-drug conjugates.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02611323 Non-Hodgkin's Lymphoma Phase 1 Recruiting December 9, 2021 - NCT03274492 Diffuse Large B-Cell Lymphoma Phase 3 Recruiting April 15, 2023 - NCT03219333 Carcinoma, Transitional Cell ... more >> Urinary Bladder Neoplasms Urologic Neoplasms Renal Pelvis Neoplasms Urothelial Cancer Ureteral Neoplasms Urethral Neoplasms Collapse << Phase 2 Recruiting May 2025 - - 更多
- 参考文献
- [1] Li D, Poon KA, et al. DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma. Mol Cancer Ther. 2013 Jul;12(7):1255-65.
- [2] Francisco JA, Cerveny CG, et al. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood. 2003 Aug 15;102(4):1458-65.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 160800-57-7 | 储存条件 |
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| 分子式 | C40H69N5O7 | 运输 | 蓝冰 | |
| 分子量 | 732.01 | 别名 | 澳瑞他汀 E;奥利斯他汀 E |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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| NCT02611323 | Non-Hodgkin's Lymphoma | Phase 1 | Recruiting | December 9, 2021 | - |
| NCT03274492 | Diffuse Large B-Cell Lymphoma | Phase 3 | Recruiting | April 15, 2023 | - |
| NCT03219333 | Carcinoma, Transitional Cell ... more >> Urinary Bladder Neoplasms Urologic Neoplasms Renal Pelvis Neoplasms Urothelial Cancer Ureteral Neoplasms Urethral Neoplasms Collapse << | Phase 2 | Recruiting | May 2025 | - |
| NCT02979522 | Hodgkin Disease | Phase 1 Phase 2 | Recruiting | October 29, 2021 | United States, Arkansas ... more >> Arkansas Children's Hospital Recruiting Little Rock, Arkansas, United States, 72202 United States, Colorado Children's Hospital Colorado Recruiting Aurora, Colorado, United States, 80045 United States, Missouri Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 United States, Ohio Cincinnati Childrens Hospital Medical Center Recruiting Cincinnati, Ohio, United States, 45229-3039 Brazil Hospital Sao Rafael S/A Recruiting Salvador, Bahia, Brazil, 41253-190 INCA - Instituto Nacional de Cancer Recruiting Rio de Janeiro, Rio Do Janeiro, Brazil, 20230-230 Hospital de Clinicas de Porto Alegre Recruiting Porto Alegre, Rio Grande Do Sul, Brazil, 90035-903 Hospital de Cancer de Barretos - Fundacao Pio XII Recruiting Barretos, Sao Paulo, Brazil, 14784-400 Jardim das Americas Recruiting Parana, Brazil, 81520-060 GRAACC - Grupo de Apoio ao Adolescente e a Crianca com Cancer Recruiting Sao Paulo, Brazil, 04023-062 ICr - Instituto da Crianca - HCFMUSP Recruiting Sao Paulo, Brazil, 05403-000 Hospital Santa Marcelina Recruiting Sao Paulo, Brazil, 08270-070 Hong Kong The Chinese University of Hong Kong Recruiting Shatin, Hong Kong, 00000 Italy Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi Recruiting Bologna, Italy, 40138 Azienda Ospedaliero Universitaria Ospedale Pediatrico Meyer Recruiting Firenze, Italy, 50139 Fondazione IRCCS Policlinico San Matteo Recruiting Pavia, Italy, 27100 Ospedale Pediatrico Bambino Gesu,UOC Onco-ematologia Recruiting Roma, Italy, 165 Azienda Ospedaliera Citta della Salute e della Scienza di Torino Recruiting Torino, Italy, 10126 Japan NHO Nagoya Medical Center Recruiting Nagoya-shi, Aichi-Ken, Japan, 460-0001 Kyushu University Hospital Recruiting Fukuoka-shi, Fukuoka-Ken, Japan, 812-8582 Hokuyukai Sapporo Hokuyu Hospital Recruiting Sapporo-shi, Hokkaido, Japan, 003-0006 St. Marianna University School of Medicine Hospital Recruiting Kawasaki-shi, Kanagawa-Ken, Japan, 216-8511 Singapore National University Cancer Institute Singapore Recruiting Singapore, Singapore, 119228 Taiwan Taichung Veterans General Hospital Recruiting Taichung, Taiwan, 40705 National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 Collapse << |
| NCT01469793 | Ovarian Cancer | Phase 1 | Completed | - | United States, Arizona ... more >> Phoenix, Arizona, United States, 85259 United States, Colorado Aurora, Colorado, United States, 80045 United States, Florida Jacksonville, Florida, United States, 32224 United States, Minnesota Rochester, Minnesota, United States, 55905 Netherlands Amsterdam, Netherlands, 1081 HV Groningen, Netherlands, 9713 GZ Collapse << |
| NCT03288545 | Carcinoma, Transitional Cell ... more >> Urinary Bladder Neoplasms Urologic Neoplasms Renal Pelvis Neoplasms Urothelial Cancer Ureteral Neoplasms Urethral Neoplasms Collapse << | Phase 1 | Recruiting | September 2024 | United States, California ... more >> University of California at San Francisco Recruiting San Francisco, California, United States, 94134 Stanford Cancer Center / Blood & Marrow Transplant Program Recruiting Stanford, California, United States, 94305 United States, Colorado University of Colorado Hospital / University of Colorado Recruiting Aurora, Colorado, United States, 80045-0510 United States, Connecticut Yale Cancer Center Recruiting New Haven, Connecticut, United States, 06520 United States, Florida University of Miami Recruiting Miami, Florida, United States, 33136 United States, Georgia Winship Cancer Institute / Emory University School of Medicine Recruiting Atlanta, Georgia, United States, 30322 United States, Illinois Cardinal Bernardin Cancer Center / Loyola University Medical Center Recruiting Maywood, Illinois, United States, 60153 United States, Kansas University of Kansas Cancer Center Recruiting Westwood, Kansas, United States, 66205 United States, Michigan University of Michigan Comprehensive Cancer Center Recruiting Ann Arbor, Michigan, United States, 48109 United States, Minnesota University of Minnesota Recruiting Minneapolis, Minnesota, United States, 55455 United States, New Jersey Hackensack University Medical Center Recruiting Hackensack, New Jersey, United States, 07601 United States, New York Roswell Park Cancer Institute Recruiting Buffalo, New York, United States, 14263 Weill Cornell Medical College Recruiting New York, New York, United States, 10065 Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10087-9049 United States, North Carolina UNC Lineberger Comprehensive Cancer Center / University of North Carolina Recruiting Chapel Hill, North Carolina, United States, 27599 Levine Cancer Institute Recruiting Charlotte, North Carolina, United States, 28204 United States, Ohio Case Western Reserve University / University Hospitals Case Medical Center Recruiting Cleveland, Ohio, United States, 44106 United States, South Carolina Medical University of South Carolina/Hollings Cancer Center Recruiting Charleston, South Carolina, United States, 29425 Collapse << |
| NCT02951117 | Multiple Myeloma | Phase 1 | Withdrawn(No participants enro... more >>lled) Collapse << | April 28, 2021 | Australia ... more >> St Vincent´s Hospital /ID# 153022 Darlinghurst, Australia, 2010 St. Vincents Hospital Melbourne /ID# 157925 Fitzroy, Australia, 3065 The Alfred Hospital /ID# 150202 Prahran, Australia, 3181 Collapse << |
| NCT01712490 | - | - | Active, not recruiting | - | - |
| NCT03070990 | Metastatic Urothelial Cancer | Phase 1 | Active, not recruiting | March 2019 | Japan ... more >> Site JP00003 Tsukuba, Ibaraki, Japan Site JP00005 Sendai, Miyagi, Japan Site JP00008 Suita, Osaka, Japan Site JP00004 Chuo, Tokyo, Japan Site JP00007 Koto, Tokyo, Japan Site JP00006 Fukuoka, Japan Site JP00001 Niigata, Japan Site JP00002 Okayama, Japan Collapse << |
| NCT02202785 | Pancreatic Adenocarcinoma | Phase 2 | Terminated(Business Decision, ... more >>No Safety or Efficacy Concerns) Collapse << | - | United States, Colorado ... more >> Aurora, Colorado, United States United States, Florida St. Petersburg, Florida, United States Tampa, Florida, United States United States, Massachusetts Boston, Massachusetts, United States United States, Ohio Cincinnati, Ohio, United States United States, Tennessee Nashville, Tennessee, United States United States, Texas San Antonio, Texas, United States Belgium Brugge, Belgium Leuven, Belgium Spain Barcelona, Spain Madrid, Spain Malaga, Spain Sevilla, Spain United Kingdom London, Greater London, United Kingdom Manchester, Greater Manchester, United Kingdom Sutton, Surrey, United Kingdom Collapse << |
| NCT01712490 | Hodgkin Lymphoma | Phase 3 | Active, not recruiting | March 1, 2020 | - |
| NCT02453087 | Non-Hodgkin's Lymphoma | Phase 1 | Active, not recruiting | September 4, 2019 | United States, California ... more >> City of Hope National Medical Center Duarte, California, United States, 91010 Stanford Cancer Center Stanford, California, United States, 94305-5820 United States, Colorado Medical Center of Aurora; Rocky Mountain Cancer Centers Aurora, Colorado, United States, 80012 United States, District of Columbia Georgetown University Medical Center Lombardi Cancer Center Washington, District of Columbia, United States, 20007 United States, Florida Florida Cancer Specialists - Sarasota (North Catttlemen Rd) Sarasota, Florida, United States, 34232 United States, New York New York University Cancer Cen New York, New York, United States, 10016 United States, Oregon Willamette Valley Cancer Ctr - 520 Country Club Eugene, Oregon, United States, 97401-8122 Collapse << |
| NCT01166490 | Gastric Neoplasms ... more >> Pancreatic Neoplasms Collapse << | Phase 1 | Completed | - | United States, Arizona ... more >> TGen Clinical Research Service at Scottsdale Healthcare Scottsdale, Arizona, United States, 85259 United States, California University of California at San Francisco San Francisco, California, United States, 94115 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637-1470 United States, Massachusetts Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, Texas Texas Oncology - Baylor Sammons Cancer Center Dallas, Texas, United States, 75246 Texas Oncology - Tyler Tyler, Texas, United States, 75702 United States, Washington Seattle Cancer Care Alliance / University of Washington Seattle, Washington, United States, 98109-1023 Collapse << |
| NCT01060904 | Disease, Hodgkin | Phase 1 | Completed | - | United States, Minnesota ... more >> Mayo Clinic Rochester, Minnesota, United States, 55905 United States, North Carolina UNC Lineberger Comprehensive Cancer Center / University of North Carolina Chapel Hill, North Carolina, United States, 27599 United States, Texas MD Anderson Cancer Center / University of Texas Houston, Texas, United States, 77030 Canada, British Columbia British Columbia Cancer Agency - Vancouver Centre Vancouver, British Columbia, Canada, V5Z 4E6 Collapse << |
| NCT00866047 | Lymphoma, Large-Cell, Anaplast... more >>ic Lymphoma, Non-Hodgkin Collapse << | Phase 2 | Completed | - | - |
| NCT02202759 | - | - | Terminated(Business Decision, ... more >>No Safety or Efficacy Concerns) Collapse << | - | - |
| NCT01026415 | Carcinomas Di... more >>sease, Hodgkin Lymphoma, Large-Cell, Anaplastic Lymphoma, Non-Hodgkin Neoplasms Collapse << | Phase 1 | Completed | - | United States, California ... more >> City of Hope Duarte, California, United States, 91010 United States, Colorado Colorado Blood Cancer Institute Denver, Colorado, United States, 80218 United States, Indiana St. Francis Medical Group Oncology & Hematology Specialists Indianapolis, Indiana, United States, 46237 United States, Michigan Karmanos Cancer Institute / Wayne State University Detroit, Michigan, United States, 48209 United States, New Jersey Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 United States, Washington Seattle Cancer Care Alliance / University of Washington Medical Center Seattle, Washington, United States, 98109-1023 Collapse << |
| NCT02202785 | - | - | Terminated(Business Decision, ... more >>No Safety or Efficacy Concerns) Collapse << | - | - |
| NCT02202759 | Adenocarcinoma of the Stomach ... more >> Gastroesophageal Junction Expressing Guanylyl Cyclase C Collapse << | Phase 2 | Terminated(Business Decision, ... more >>No Safety or Efficacy Concerns) Collapse << | - | United States, Colorado ... more >> Aurora, Colorado, United States United States, Florida St. Petersburg, Florida, United States Tampa, Florida, United States United States, Massachusetts Boston, Massachusetts, United States United States, Ohio Cincinatti, Ohio, United States United States, Tennessee Nasheville, Tennessee, United States Nashville, Tennessee, United States Belgium Brugge, Belgium Brussels, Belgium Bruxelles, Belgium Leuven, Belgium Spain Barcelona, Spain Madrid, Spain Malaga, Spain Sevilla, Spain United Kingdom London, Greater London, United Kingdom Manchester, Greater Manchester, United Kingdom Sutton, Surrey, United Kingdom Collapse << |
| NCT01309789 | Lymphoma, Large-Cell, Anaplast... more >>ic Lymphoma, NK-cell Lymphoma, T-cell Collapse << | Phase 1 | Completed | - | United States, Alabama ... more >> UAB Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3300 United States, California City of Hope National Medical Center Duarte, California, United States, 91010 Stanford Cancer Center Stanford, California, United States, 94305 United States, Missouri Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, New York Memorial Sloan Kettering Cancer Center New York, New York, United States, 10021 United States, Pennsylvania Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111 United States, South Carolina St. Francis Hospital Greenville, South Carolina, United States, 29601 United States, Texas MD Anderson Cancer Center / University of Texas Houston, Texas, United States, 77030-4000 United States, Washington Seattle Cancer Care Alliance / University of Washington Medical Center Seattle, Washington, United States, 98109 United Kingdom Christie Hospital NHS Foundation Trust Manchester, United Kingdom, M20 4BX Southampton General Hospital Southampton, United Kingdom, SO16 6YD Collapse << |
| NCT01925612 | Lymphoma, B-cell ... more >> Lymphoma, Large B-cell, Diffuse Collapse << | Phase 2 | Terminated(Sponsor decision ba... more >>sed on portfolio prioritization and changing treatment landscape in frontline DLBCL) Collapse << | - | - |
| NCT00866047 | - | - | Completed | - | - |
| NCT00649584 | Disease, Hodgkin ... more >> Lymphoma, Large-Cell, Anaplastic Lymphoma, Non-Hodgkin Collapse << | Phase 1 | Terminated(Sponsor decision no... more >>t to enroll cohorts of combined SGN-35 and gemcitabine therapy.) Collapse << | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294-3300 United States, California Stanford University Medical Center Palo Alto, California, United States, 94305 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Missouri Washington University School of Medicine St. Louis, Missouri, United States, 63110 United States, Texas University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030-4003 Collapse << |
| NCT01777152 | Anaplastic Large-Cell Lymphoma... more >> Non-Hodgkin Lymphoma T-Cell Lymphoma Collapse << | Phase 3 | Active, not recruiting | December 2019 | - |
| NCT01925612 | - | - | Terminated(Sponsor decision ba... more >>sed on portfolio prioritization and changing treatment landscape in frontline DLBCL) Collapse << | - | - |
| NCT01950364 | Hodgkin Lymphoma ... more >> Anaplastic Large-cell Lymphoma Collapse << | Phase 1 | Completed | - | Belgium ... more >> Brussels, Belgium Gent, Belgium Lithuania Vilnius, Lithuania Spain Barcelona, Spain Madrid, Spain Salamanca, Spain Collapse << |
| NCT02391038 | Advanced Gastrointestinal Carc... more >>inoma Gastroesophageal Junction Adenocarcinoma Recurrent Gastric Adenocarcinoma Recurrent Gastroesophageal Junction Adenocarcinoma Metastatic Gastric Adenocarcinoma Metastatic Gastroesophageal Junction Adenocarcinoma Recurrent Gastrointestinal Carcinoma Collapse << | Phase 1 | Terminated(The study was termi... more >>nated because preliminary PK and overall clinical data demonstrated compelling similarity between Western and Asian participant populations.) Collapse << | - | Japan ... more >> Kashiwa-shi, Chiba-Ken, Japan Minato-ku, Tokyo-To, Japan Korea, Republic of Seoul, Gyeonggi-do, Korea, Republic of Taiwan Taipei, Taiwan Collapse << |
| NCT01950364 | - | - | Completed | - | - |
| NCT01909934 | Anaplastic Large-cell Lymphoma | Phase 4 | Recruiting | April 23, 2020 | - |
| NCT02391038 | - | - | Terminated(The study was termi... more >>nated because preliminary PK and overall clinical data demonstrated compelling similarity between Western and Asian participant populations.) Collapse << | - | - |
| NCT01969643 | Breast Cancer | Phase 1 | Recruiting | July 2020 | - |
| NCT01577758 | - | - | Completed | - | - |
| NCT02572167 | Hodgkin Lymphoma | Phase 1 Phase 2 | Active, not recruiting | October 2020 | United States, California ... more >> City of Hope National Medical Center Duarte, California, United States, 91010-3000 Stanford Cancer Center Stanford, California, United States, 94305 United States, Massachusetts Dana Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, Michigan Karmanos Cancer Institute / Wayne State University Detroit, Michigan, United States, 48201 United States, Minnesota Mayo Clinic Minnesota Rochester, Minnesota, United States, 55905 United States, Missouri Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, Nebraska University of Nebraska Medical Center Omaha, Nebraska, United States, 68198-7680 United States, New Jersey Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 United States, New York Memorial Sloan Kettering Cancer Center - Commack Commack, New York, United States, 11725 Memorial Sloan Kettering Cancer Center New York, New York, United States, 10021 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Ohio James Cancer Hospital / Ohio State University Columbus, Ohio, United States, 43210 United States, Texas Charles A. Sammons Cancer Center / Baylor University Medical Center Dallas, Texas, United States, 75246 Collapse << |
| NCT02610062 | Acute Myeloid Leukemia | Phase 1 | Terminated(Business decision b... more >>y sponsor) Collapse << | - | United States, California ... more >> Site US0006 Duarte, California, United States, 91010 United States, New York Site US0004 New York, New York, United States, 10016 United States, Texas Site US0001 Houston, Texas, United States, 77030 Canada, Ontario Site CA0010 Toronto, Ontario, Canada, M5G 2M9 Collapse << |
| NCT02091999 | Metastatic Urothelial Cancer a... more >>nd Other Malignant Solid Tumors Collapse << | Phase 1 | Recruiting | December 2020 | - |
| NCT01577758 | Advanced Gastrointestinal Mali... more >>gnancies Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> Moffitt Cancer Center Tampa, Florida, United States, 33612 Collapse << |
| NCT01691898 | Follicular Lymphoma ... more >> Diffuse Large B-Cell Lymphoma Collapse << | Phase 1 Phase 2 | Active, not recruiting | February 12, 2019 | - |
| NCT02175433 | Relapsed Lymphoid Malignancy ... more >> Refractory Lymphoid Malignancy Collapse << | Phase 1 | Active, not recruiting | June 2019 | United States, California ... more >> Site US0006 Duarte, California, United States, 91010 Site US0002 Stanford, California, United States, 94305 United States, Kansas Site US0004 Fairway, Kansas, United States, 66205 United States, New York Site US0001 New York, New York, United States, 10019 Canada, British Columbia Site CA0005 Vancouver, British Columbia, Canada, V5Z 4E6 Collapse << |
| NCT01963052 | Metastatic Urothelial Cancer | Phase 1 | Active, not recruiting | March 2019 | United States, Alabama ... more >> Site US00006 Birmingham, Alabama, United States, 35294 United States, Connecticut Site US00002 New Haven, Connecticut, United States, 06510 United States, Michigan Site US00001 Detroit, Michigan, United States, 48201 United States, Missouri Site US00003 Saint Louis, Missouri, United States, 63110 United States, New York Site US00009 Buffalo, New York, United States, 14263 United States, Pennsylvania Site US00011 Pittsburgh, Pennsylvania, United States, 15232 United States, Tennessee Site US00010 Nashville, Tennessee, United States, 37212 United States, Washington Site US00008 Seattle, Washington, United States, 98109 Canada, British Columbia Site CA00004 Vancouver, British Columbia, Canada, V5Z 1H5 Canada, Ontario Site CA00007 Hamilton, Ontario, Canada, L8V 5C2 Site CA00005 Toronto, Ontario, Canada, M4N 3M5 Collapse << |
| NCT01841021 | - | - | Terminated(Slow accrual, loss ... more >>of sponsor support) Collapse << | - | - |
| NCT01841021 | Peripheral T-Cell Lymphoma | Not Applicable | Terminated(Slow accrual, loss ... more >>of sponsor support) Collapse << | - | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 Collapse << |
| NCT01492088 | Relapsed or Refractory Hodgkin... more >> Lymphoma Relapsed or Refractory Anaplastic Large-cell Lymphoma Collapse << | Phase 1 Phase 2 | Completed | - | United States, Colorado ... more >> Aurora, Colorado, United States United States, Missouri Kansas City, Missouri, United States United States, New York New York, New York, United States United States, Texas Houston, Texas, United States France Bordeaux Cedex, France Lyon, France Paris Cedex 12, France Germany Berlin, Germany Frankfurt, Germany Giessen, Germany Halle, Germany Munster, Germany Italy Padova, Italy Roma, Italy Mexico Mexico Df, Mexico Netherlands Rotterdam, Netherlands Spain Barcelona, Spain United Kingdom London, United Kingdom Collapse << |
| NCT01691898 | - | - | Active, not recruiting | - | - |
| NCT01990534 | Hodgkin Lymphoma | Phase 4 | Active, not recruiting | March 2020 | Czech Republic ... more >> Praha, Prague, Czech Republic Brno, Czech Republic Germany Heidelberg, Baden Wuerttemberg, Germany Koeln, Germany Malaysia Georgetown, Penang, Malaysia Ampang, Selangor, Malaysia Kuala Lumpur, Malaysia Poland Gdansk, Poland Krakow, Poland Warszawa, Poland Spain Pamplona, Navarra, Spain Madrid, Spain Thailand Bangkoknoi, Bangkok, Thailand Patumwan, Bangkok, Thailand Ratchathewi, Bangkok, Thailand Turkey Izmir, Bornova, Turkey Ankara, Turkey Izmir, Turkey Collapse << |
| NCT01363947 | Non-Small Cell Lung Cancer, Ov... more >>arian Cancer Collapse << | Phase 1 | Completed | - | United States, Arizona ... more >> HonorHealth Research Institute - Pima Center Scottsdale, Arizona, United States, 85258 United States, Connecticut Smilow Cancer Hospital at Yale New Haven New Haven, Connecticut, United States, 06510 United States, Tennessee Sarah Cannon Research Inst. Nashville, Tennessee, United States, 37203 United States, Texas Univ of Texas SW Medical Ctr Dallas, Texas, United States, 75390 Spain Hospital del Mar; Servicio de Oncologia Barcelona, Spain, 08003 Hospital Univ Vall d'Hebron; Servicio de Oncologia Barcelona, Spain, 08035 Hospital General Universitario Gregorio Marañon; Servicio de Oncologia Madrid, Spain, 28007 Collapse << |
| NCT01990534 | - | - | Active, not recruiting | - | - |
| NCT01421667 | - | - | Completed | - | - |
| NCT01461538 | Acute Lymphoid Leukemia ... more >> Acute Myeloid Leukemia Anemia, Refractory, With Excess of Blasts Solid Tumors Collapse << | Phase 2 | Completed | - | - |
| NCT02780011 | CD30-positive Lymphoma ... more >> CD30-positive Solid Tumor Collapse << | Phase 1 | Withdrawn(lack of funding) | September 2018 | United States, Texas ... more >> Houston Methodist Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT01492088 | - | - | Completed | - | - |
| NCT01461538 | - | - | Completed | - | - |
| NCT01396070 | - | - | Completed | - | - |
| NCT01421667 | Lymphoma, B-Cell ... more >> Lymphoma, Large B-Cell, Diffuse Lymphoma, Non-Hodgkin Lymphoma, T-Cell Collapse << | Phase 2 | Completed | - | - |
| NCT02388490 | Relapsed or Refractory EBV-and... more >> CD30-positive Lymphomas Collapse << | Phase 2 | Active, not recruiting | September 2018 | Korea, Republic of ... more >> Seoul National University Bundang Hospital Seongnam, Korea, Republic of Seoul National Unversity Hospital Seoul, Korea, Republic of SMG-SNU Boramae Medical Center Seoul, Korea, Republic of Collapse << |
| NCT01396070 | Non-Hodgkin Lymphoma (NHL) ... more >> Cutaneous Lymphoma Cutaneous T-cell Lymphoma (CTCL) Mycosis Fungoides Sezary Syndrome Collapse << | Phase 2 | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
| NCT01508312 | Hodgkin's Lymphoma | Phase 2 | Active, not recruiting | September 2019 | United States, New York ... more >> Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Collapse << |
| NCT02588651 | T-cell Lymphoma ... more >> Angioimmunoblastic T-cell Lymphoma Hepato-splenic T-cell Lymphoma Adult T-cell Leukemia/Lymphoma Enteropathy Associated T-cell Lymphoma NK T-cell Lymphoma Transformed Mycosis Fungoides Collapse << | Phase 2 | Recruiting | December 2022 | United States, Michigan ... more >> University of Michigan Recruiting Ann Arbor, Michigan, United States, 48109-5413 Contact: Ryan Wilcox, MD rywilcox@umich.edu Principal Investigator: Ryan Wilcox, MD Wayne State University, Karmanos Cancer Institute Recruiting Detroit, Michigan, United States, 48201 Contact: Radhakrishnan Ramchandren, MD 313-576-8739 ramchanr@karmanos.org Principal Investigator: Radhakrishnan Ramchandren, MD United States, New Jersey Hackensack University Medical Center Recruiting Hackensack, New Jersey, United States, 07601 Contact: Tatyana Feldman, MD 551-996-5900 Tatyana.Feldman@HackensackMeridian.org Principal Investigator: Tatyana Feldman, MD United States, Ohio University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center Recruiting Cleveland, Ohio, United States, 44106 Contact: Paolo Caimi, MD 216-844-0139 Paolo.Caimi@uhhospitals.org Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center Recruiting Cleveland, Ohio, United States, 44195 Contact: Deepa Jagadeesh, MD, MPH 216-444-0857 jagaded@ccf.org Collapse << |
| NCT03574753 | Recurrent Squamous Cell Lung C... more >>arcinoma Stage IV Squamous Cell Lung Carcinoma AJCC V7 Collapse << | Phase 2 | Recruiting | January 5, 2022 | United States, Texas ... more >> M D Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Vassiliki A. Papadimitrakopoulou 713-792-3245 vpapadim@mdanderson.org Principal Investigator: Vassiliki A. Papadimitrakopoulou Collapse << |
| NCT02713828 | Squamous Cell Carcinoma of the... more >> Lung Collapse << | Phase 1 Phase 2 | Terminated(Company discontinue... more >>d further development of study drug for this indication) Collapse << | - | United States, Florida ... more >> University of Miami Hospital Miami, Florida, United States, 33136 United States, Georgia Emory University Winship Cancer Institute Atlanta, Georgia, United States, 30322 United States, Louisiana Ochsner Medical Center New Orleans, Louisiana, United States, 70121 United States, Nebraska Missouri Valley Cancer Consortium Omaha, Nebraska, United States, 68106 United States, New Jersey Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey, United States, 08903 United States, New York Stony Brook University Stony Brook, New York, United States, 11794-9446 United States, Pennsylvania Penn State Hershey Cancer Institute Hershey, Pennsylvania, United States, 17033 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75390 United States, West Virginia West Virginia University Morgantown, West Virginia, United States, 26506 United States, Wisconsin Gundersen Health System La Crosse, Wisconsin, United States, 54601 Collapse << |
