CAS No.: 12192-57-3
Aurothioglucose/金硫葡萄糖 Catalog No. CSN16891
Synonyms: Gold thioglucose;Solganal;SKF-10056
Aurothioglucose is a well known active-site inhibitor of TrxR1, inhibited TrxR1 activity in HeLa cell cytosol but had no effect on the viability of the cells.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01557348 - - Completed - - NCT01557348 - - Completed - - - 参考文献
- [1] Britt RD Jr, Velten M, et al. The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndrome. Antioxid Redox Signal. 2014 Jun 10;20(17):2681-91.
- [2] Watson WH, Heilman JM, et al. Thioredoxin reductase-1 knock down does not result in thioredoxin-1 oxidation. Biochem Biophys Res Commun. 2008 Apr 11;368(3):832-6.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 12192-57-3 | 储存条件 |
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| 分子式 | C6H11AuO5S | 运输 | 蓝冰 | |
| 分子量 | 392.18 | 别名 | Gold thioglucose;Solganal;SKF-10056;金硫葡萄糖 |
