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CAS No.: 305-84-0
Synonyms: Karnozin;Karnozzn;肌肽
L-carnosine is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart, it can scavenge oxygen free radicals and transition metal ions, block protein-protein and protein-DNA cross-links induced by hypochlorite anions and toxic aldehydes, inhibit nonenzymatic protein glycation induced by aldose and ketose reducing sugars and inhibit the formation of toxic advanced glycation end products (AGE).
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT03708185 | Healthy | Not Applicable | Recruiting | September 30, 2020 | United Kingdom ... more >> School of Sports and Health Sciences Recruiting Exeter, Devon, United Kingdom, EX4 4JA Contact: David J Childs 01392 722771 ext 2771 d.j.childs@exeter.ac.uk Collapse << |
NCT02515032 | Cachexia NSCL... more >>C Collapse << | Not Applicable | Completed | - | Croatia ... more >> GH Varaždin Varaždin, Croatia, 42 000 GH Zadar Zadar, Croatia, 23 000 CHC Sestre Milosrdnice Zagreb, Croatia, 10 000 CHC Zagreb, Zagreb, Croatia, 10 000 Italy Policlinico Universitario Campus Bio-Medico di Roma Rome, Italy, 00128 Policlinico Tor Vergata Rome, Italy, 00133 Azienda Ospedaliera San Camillo Forlanini Rome, Italy, 00151 Slovakia FNsP F.D. Roosvelta Banská Bystrica Banská Bystrica, Slovakia, 975 17 Nemocnica Sv. Jakuba Bardejov, Slovakia, 085 01 Východoslovenský onkologický ústav Košice, Slovakia, 041 91 NsP Štefana Kukuru Michalovce Michalovce, Slovakia, 071 01 FNsP J.A. Reimana Prešov, Slovakia, 081 81 Sweden Linkoping University Hospital Linkoping, Sweden, 58185 Akademiska hospital Uppsala, Sweden, 751 85 Collapse << |
NCT03087721 | Metabolic Syndrome ... more >> Insulin Resistance Collapse << | Not Applicable | Recruiting | May 31, 2019 | Colombia ... more >> IPS-Universitaria Recruiting Medellin, Antioquia, Colombia Contact: Jaime Gallo, MD, MSc +5742196060 jaime.gallo@udea.edu.co Collapse << |
实验方案
技术信息
CAS号 | 305-84-0 | 储存条件 |
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分子式 | C9H14N4O3 | 运输 | 蓝冰 | |||||
分子量 | 226.23 | 别名 | Karnozin;Karnozzn;肌肽;L-肌肽 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT03708185 | Healthy | Not Applicable | Recruiting | September 30, 2020 | United Kingdom ... more >> School of Sports and Health Sciences Recruiting Exeter, Devon, United Kingdom, EX4 4JA Contact: David J Childs 01392 722771 ext 2771 d.j.childs@exeter.ac.uk Collapse << |
NCT02515032 | Cachexia NSCL... more >>C Collapse << | Not Applicable | Completed | - | Croatia ... more >> GH Varaždin Varaždin, Croatia, 42 000 GH Zadar Zadar, Croatia, 23 000 CHC Sestre Milosrdnice Zagreb, Croatia, 10 000 CHC Zagreb, Zagreb, Croatia, 10 000 Italy Policlinico Universitario Campus Bio-Medico di Roma Rome, Italy, 00128 Policlinico Tor Vergata Rome, Italy, 00133 Azienda Ospedaliera San Camillo Forlanini Rome, Italy, 00151 Slovakia FNsP F.D. Roosvelta Banská Bystrica Banská Bystrica, Slovakia, 975 17 Nemocnica Sv. Jakuba Bardejov, Slovakia, 085 01 Východoslovenský onkologický ústav Košice, Slovakia, 041 91 NsP Štefana Kukuru Michalovce Michalovce, Slovakia, 071 01 FNsP J.A. Reimana Prešov, Slovakia, 081 81 Sweden Linkoping University Hospital Linkoping, Sweden, 58185 Akademiska hospital Uppsala, Sweden, 751 85 Collapse << |
NCT03087721 | Metabolic Syndrome ... more >> Insulin Resistance Collapse << | Not Applicable | Recruiting | May 31, 2019 | Colombia ... more >> IPS-Universitaria Recruiting Medellin, Antioquia, Colombia Contact: Jaime Gallo, MD, MSc +5742196060 jaime.gallo@udea.edu.co Collapse << |
NCT02999581 | Dietary Modification | Not Applicable | Completed | - | - |
NCT00810225 | - | - | Completed | - | United States, District of Col... more >>umbia Georgetown University Washington, District of Columbia, United States, 20007 Collapse << |
NCT03612414 | Xerostomia Due to Hyposecretio... more >>n of Salivary Gland pH Saliva Quality of Life Collapse << | Not Applicable | Completed | - | Italy ... more >> Università degli Studi dell'Insubria Varese, Italy, 21100 Collapse << |
NCT03655041 | Sports Nutritional Physiologic... more >>al Phenomena Collapse << | Not Applicable | Completed | - | - |
NCT01314040 | Identify New Biomarkers in Blo... more >>od or Urine After Consumption of Meat Protein, Dairy Protein and Grain Protein in Healthy Subjects. Collapse << | Not Applicable | Completed | - | Netherlands ... more >> Wageningen University Wageningen, Gelderland, Netherlands, 6700 EV Collapse << |
NCT01963767 | Aging | Phase 2 | Completed | - | United States, Florida ... more >> University of South Florida Tampa, Florida, United States, 33620 Collapse << |
NCT03111979 | Muscle Function | Phase 4 | Suspended(Time restrictions on... more >> leading investigator) Collapse << | October 2018 | - |
NCT01818830 | - | - | Unknown | - | China, Beijing ... more >> Chinese PLA General Hospital Beijing, Beijing, China, 100853 Collapse << |
NCT01745016 | Exercise Fati... more >>gue Collapse << | Not Applicable | Completed | - | United States, North Carolina ... more >> UNC Exercise and Sport Science Chapel Hill, North Carolina, United States, 27599 Collapse << |
NCT02709837 | Nutrition | Not Applicable | Completed | - | - |
NCT02770417 | Chronic Obstructive Pulmonary ... more >>Disease (COPD) Collapse << | Not Applicable | Recruiting | February 2019 | Belgium ... more >> Jessa Ziekenhuis (ReGo) Recruiting Hasselt, Belgium, 3500 Contact: Jana De Brandt, drs. jana.debrandt@uhasselt.be Collapse << |
NCT03601962 | Xerostomia As... more >>ialia Hyposalivation Mouth Dryness Collapse << | Not Applicable | Recruiting | December 31, 2018 | Italy ... more >> Fondazione IRCCS Istituto Nazionale dei Tumori Recruiting Milan, Italy, 20100 Contact: Ester Orlandi, MD +39.02.23900 ext 4000 Ester.Orlandi@istitutotumori.mi.it Collapse << |
NCT03418376 | Multiple Sclerosis ... more >> Exercise Therapy Dietary Supplement Collapse << | Not Applicable | Completed | - | Belgium ... more >> Hasselt University Diepenbeek, Limburg, Belgium, 3590 Collapse << |
NCT03194334 | Dietary Modification | Not Applicable | Completed | - | - |
NCT00813553 | Healthy | Not Applicable | Completed | - | Switzerland ... more >> University and Inselspital Bern, Switzerland, 3010 Collapse << |
NCT03314987 | Toxicity | Not Applicable | Not yet recruiting | March 13, 2022 | - |
NCT03330470 | Subjective Cognitive Impairmen... more >>t Mild Cognitive Impairment Parkinson Disease Healthy Volunteers Collapse << | Not Applicable | Recruiting | December 31, 2020 | Slovakia ... more >> University Hospital Bratislava, Comenius University Active, not recruiting Bratislava, Slovakia, 81369 Biomedical Research Center, Slovak Academy of Sciences Recruiting Bratislava, Slovakia, 84505 Contact: Barbara Ukropcová, Assoc. Prof., MD, PhD +421 2 32295 2261 barbara.ukropcova@savba.sk Principal Investigator: Jozef Ukropec, DrSC., PhD Sub-Investigator: Lucia Slobodová, Mgr. Sub-Investigator: Martin Schon, MD Taiwan Laboratory of Cognitive Neurophysiology, Institute of Physical Education, Health & Leisure Studies, National Cheng Kung University Active, not recruiting Tainan City, Tainan, Taiwan, 701 Collapse << |
NCT00721708 | Oxidative Stress | Not Applicable | Completed | - | United States, Massachusetts ... more >> Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University Boston, Massachusetts, United States, 02111 Collapse << |
NCT00149149 | Healthy | Phase 1 | Unknown | - | United Kingdom ... more >> Imperial College Recruiting London, United Kingdom, W12 0NN Contact: Asif Mahmood, MD 02083838067 asif.mahmood@imperial.ac.uk Sub-Investigator: Asif Mahmood, MRCP Principal Investigator: Raymond Playford, FRCP, PhD Collapse << |
NCT02928250 | Type 1 Diabetes ... more >> Oxidative Stress Carnosine Diabetic Nephropathy Collapse << | Not Applicable | Completed | - | - |
NCT02011100 | Metabolic Diseases, Type 2 Dia... more >>betes, Cardiovascular Disease Collapse << | Not Applicable | Completed | - | Slovakia ... more >> Univeristy Hospital in Bratislava Bratislava, Slovakia, 81369 Institute of Experimental Endocrinology Slovak Academy of Sciences Bratislava, Slovakia, 83306 Collapse << |
NCT02604927 | Spinal Cord Injuries | Not Applicable | Unknown | September 2017 | Brazil ... more >> School of Physical Education and Sports, University of Sao Paulo Not yet recruiting São Paulo, Brazil, 05508-030 Contact: Guilherme Artioli, PhD 55 11 3091-3096 artioli@usp.br Collapse << |
NCT00810368 | Persian Gulf Syndrome | Phase 2 | Completed | - | United States, District of Col... more >>umbia Georgetown University Washington, District of Columbia, United States, 20007 Collapse << |
NCT02686996 | Insulin Sensitivity | Not Applicable | Recruiting | June 12, 2020 | Australia, Victoria ... more >> Monash Centre for Health Research and Implementation Recruiting Melbourne, Victoria, Australia, 3168 Contact: Barbora de Courten, MD,PHD,MPH +61 3 9594 7086 barbora.decourten@monash.edu Principal Investigator: Barbora de Courten, MD,PHD,MPH Sub-Investigator: Helena Teede, MBBS,PhD Sub-Investigator: James Cameron, MBBS,MD Sub-Investigator: Alexander Hodge, BSc,MBBS,PHD Collapse << |
NCT03467438 | Gastroesophageal Reflux Diseas... more >>e Collapse << | Phase 4 | Not yet recruiting | April 1, 2019 | Italy ... more >> Fondazione IRCCS Policlinico San Matteo Pavia, Italy, 27100 Collapse << |
NCT02917928 | Poor Glycemic Control ... more >> Cardiovascular Risk Factors Cognitive Function 1, Social Collapse << | Phase 2 | Recruiting | August 2020 | Australia, Victoria ... more >> Monash Centre for Health Research and Implementation Recruiting Melbourne, Victoria, Australia, 3168 Contact: Barbora de Courten, MD,PHD,MPH +61 3 857 22651 barbora.decourten@monash.edu Principal Investigator: Barbora de Courten, MD,PHD,MPH Sub-Investigator: Helena Teede, MBBS,PhD Sub-Investigator: James Cameron, MBBS,MD Sub-Investigator: Alexander Hodge, BSc,MBBS,PHD Sub-Investigator: David Scott, BSc,MBBS,PHD Collapse << |
NCT00177177 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Not Applicable | Completed | - | United States, Pennsylvania ... more >> Mayview State Hospital Bridgeville, Pennsylvania, United States, 15107-1599 Dubois Regional Medical Center Dubois, Pennsylvania, United States, 15801 Mon-Yough Community Services, Inc. McKeesport, Pennsylvania, United States, 15132 Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
NCT01963767 | - | - | Completed | - | - |
NCT02686697 | Schizophrenia | Phase 2 Phase 3 | Recruiting | April 2019 | United States, New York ... more >> Icahn School of Medicine at Mount Sinai Recruiting New York, New York, United States, 10029 Principal Investigator: Avi Reichenberg, PhD Collapse << |
NCT00177463 | Bipolar I Disorder | Not Applicable | Completed | - | United States, Pennsylvania ... more >> Mayview State Hospital Bridgeville, Pennsylvania, United States, 15017 Mon-Yough Community Services, Inc. McKeesport, Pennsylvania, United States, 15132 Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
NCT02808624 | Peripheral Neuropathy ... more >> Cancer Collapse << | Phase 1 Phase 2 | Completed | - | Egypt ... more >> Cairo University Cairo, Kasr el Aini, Egypt Collapse << |
NCT00810368 | - | - | Completed | - | - |
NCT02819505 | Muscle Function | Phase 4 | Completed | - | - |
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