CAS No.: 1235449-52-1
BEBT-908 Catalog No. CSN17605
Synonyms: PI3Kα inhibitor 1;PI3Kalpha Inhibitor 1;CUDC-908
BEBT-908 is a PI3Kα inhibitor with an IC50 < 0.1 μM, and also inhibits HDAC (0.1 μM ≤ IC50 ≤ 1 μM) .
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Ibrahim MA, Abou-Seri SM, et al. Design, synthesis and biological evaluation of novel condensed pyrrolo[1,2-c] pyrimidines featuring morpholine moiety as PI3Kα inhibitors. Eur J Med Chem. 2015 Jun 24;99:1-13.
- [2] Li J, Qian C, et al. BEBT-908: A novel potent PI3K/HDAC inhibitor against diffuse large B-cell lymphoma. Biochem Biophys Res Commun. 2017 Sep 30;491(4):939-945.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1235449-52-1 | 储存条件 |
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| 分子式 | C23H25N9O3S | 运输 | 蓝冰 | |
| 分子量 | 507.57 | 别名 | PI3Kα inhibitor 1;PI3Kalpha Inhibitor 1;CUDC-908;MDK-9521;PI3Kα-IN-243;CUDC908, |
