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CAS No.: 86541-74-4
Synonyms: CGS14824A;Benazepril (hydrochloride);Benazepril
Benazepril HCl is an ACE inhibitor, primarily used in treatment of hypertension. Benazepril HCl is the HCl form of Benazepril.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
NCT01076205 | - | - | Completed | - | - |
NCT01669434 | - | - | Completed | - | - |
实验方案
技术信息
CAS号 | 86541-74-4 | 储存条件 |
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分子式 | C24H29ClN2O5 | 运输 | 蓝冰 | |||||||||
分子量 | 460.95 | 别名 | CGS14824A;Benazepril (hydrochloride);Benazepril;benazepril hydrochloride;benzazepril;Briem;Cibacène;Cibacen;Labopal;Lotensin;盐酸贝那普利 | |||||||||
溶解度 |
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动物实验配方 |
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NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
NCT01076205 | - | - | Completed | - | - |
NCT01669434 | - | - | Completed | - | - |
NCT01715584 | Hypertension | Phase 4 | Recruiting | December 31, 2019 | Canada, Ontario ... more >> London Health Sciences Centre - Victoria Campus Recruiting London, Ontario, Canada, N6A 5W9 Contact: Craig J Railton, MD, PhD 519 685 8500 ext 58525 Craig.Railton@lhsc.on.ca Principal Investigator: Craig J Railton, MD, PhD Sub-Investigator: Jonathan Fairbairn, BSc Sub-Investigator: George Nicoloau, MD Sub-Investigator: Robert Gros, PhD Sub-Investigator: Jason Franklin, MD Sub-Investigator: John Yoo, MD Sub-Investigator: Kevin Fung, MD Sub-Investigator: Anthony Nichols, MD Sub-Investigator: Danielle McNeil, MD Collapse << |
NCT00170950 | Hypertension | Phase 3 | Terminated(The study was termi... more >>nated early because of significant efficacy results for the primary endpoint in favor of benazepril/amlodipine treatment.) Collapse << | - | United States, New Jersey ... more >> Novartis Pharmaceuticals E. Hanover, New Jersey, United States, 07936 Denmark sites in Denmark Denmark, Denmark Finland sites in Finland Finland, Finland Norway sites in Norway Norway, Norway Sweden sites in Sweden Sweden, Sweden Collapse << |
NCT01669434 | Hypotension on Induction | Phase 4 | Completed | - | United States, Nebraska ... more >> University of Nebraska Medical Center Omaha, Nebraska, United States, 68198 Collapse << |
NCT01867047 | Adverse Effects of Angiotensin... more >>-converting-enzyme Inhibitors Hypotension Collapse << | Not Applicable | Terminated(Following an interi... more >>m analysis the study team felt that there was enough data that showed no significant difference.) Collapse << | - | United States, North Carolina ... more >> Duke University Durham, North Carolina, United States, 27710 Collapse << |
NCT00170950 | - | - | Terminated(The study was termi... more >>nated early because of significant efficacy results for the primary endpoint in favor of benazepril/amlodipine treatment.) Collapse << | - | - |
NCT01603940 | Hypertension ... more >>Diabetes Mellitus Collapse << | Phase 4 | Completed | - | Brazil ... more >> Hospital Universitario Pedro Ernesto Rio de Janeiro, RJ, Brazil, 20551030 Collapse << |
NCT00171119 | Hypertension ... more >>Diabetic Nephropathy Collapse << | Phase 4 | Terminated | - | Switzerland ... more >> Novartis Pharmaceuticals Basel, Switzerland Collapse << |
NCT00000620 | - | - | Completed | - | - |
NCT01867047 | - | - | Terminated(Following an interi... more >>m analysis the study team felt that there was enough data that showed no significant difference.) Collapse << | - | - |
NCT00630708 | Renal Insufficiency, Chronic | Not Applicable | Terminated(Significant differe... more >>nces observed between groups.) Collapse << | - | China, Guangdong ... more >> Renal Division, Nanfang Hospital,Southern Medical University Guangzhou, Guangdong, China, 510515 Collapse << |
NCT01603940 | - | - | Completed | - | - |
NCT02532777 | Henoch-Schoenlein Purpura Neph... more >>ritis Collapse << | Phase 2 | Recruiting | July 2020 | China, Jiangsu ... more >> Nanjing Children's Hospital Recruiting Nanjing, Jiangsu, China, 210000 Contact: Aihua Zhang, M.D. +8618951769017 bszah@163.com Collapse << |
NCT01375322 | Hypertension ... more >>Diabetes Mellitus, Type 2 Albuminuria Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Chang Gung Memorial Hospital-Kaohsiung Kaohsiung, Taiwan, 833 Taichung Veterans General Hospital Taichung, Taiwan, 407 Tri-Service General Hospital Taipei, Taiwan, 114 Far Eastern Memorial Hospital Taipei, Taiwan, 220 Collapse << |
NCT00367978 | Hypertension | Phase 4 | Completed | - | United States, New Jersey ... more >> Novartis Pharmaceuticals Corporation East Hanover, New Jersey, United States, 07936 Collapse << |
NCT00907374 | Microalbuminuria | Not Applicable | Completed | - | United States, California ... more >> Charles Drew University Los Angeles, California, United States, 90059 Collapse << |
NCT00907374 | - | - | Completed | - | - |
NCT02532790 | Henoch-Schoenlein Purpura Neph... more >>ritis Collapse << | Phase 2 | Recruiting | July 2020 | China, Jiangsu ... more >> Nanjing Children's Hospital Recruiting Nanjing, Jiangsu, China, 210000 Contact: Aihua Zhang, M.D. +8618951769017 bszah@163.com Collapse << |
NCT01095939 | Renal Alteration | Phase 3 | Completed | - | Switzerland ... more >> Geneva University Hospitals Geneva, Switzerland Centre Hospitalier Universitaire Vaudois Lausanne, Switzerland Collapse << |
NCT03591471 | Henoch-Schönlein Purpura Nephr... more >>itis Collapse << | Phase 1 Phase 2 | Recruiting | December 2018 | China, Henan ... more >> Children's Hospital, The First Affiliated Hospital of HUTCM Recruiting Zhengzhou, Henan, China, 450000 Contact: Ying Ding, Director +86-13503840642 dingying3236@sina.com Contact: Xia Zhang, secretary +86-13838276039 zhangxia_125@163.com Principal Investigator: Ying Ding, Director The First Affiliated Hospital of Henan University of Traditional Chinese Medicine Recruiting Zhengzhou, Henan, China, 450000 Contact: Ying Ding, MD +86-371-66221361 dingying3236@sina.com Contact: Xia zhang, MD +86-371-13213210370 ardar123@sina.com Principal Investigator: Jiansheng Li, MD Collapse << |
NCT01234922 | Hypertension ... more >>Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 2 | Terminated(slow accrual) | - | United States, North Carolina ... more >> Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 Collapse << |
NCT00234871 | Hypertension ... more >>Diabetes Proteinuria Collapse << | Phase 4 | Completed | - | - |
NCT00136851 | Hypertension | Phase 4 | Completed | - | United States, New Jersey ... more >> Novartis Pharmaceuticals East Hanover, New Jersey, United States, 07936 Collapse << |
NCT00836576 | Healthy | Phase 1 | Completed | - | United States, Missouri ... more >> Gateway Medical Research, Inc. St. Charles, Missouri, United States, 63301 Collapse << |
NCT00649597 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
NCT00649038 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
NCT01234922 | - | - | Terminated(slow accrual) | - | - |
NCT00649402 | Healhty | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT00778674 | Healthy | Not Applicable | Completed | - | United States, North Carolina ... more >> aaiPharma, Inc. Chapel Hill, North Carolina, United States, 27517 Collapse << |
NCT00836537 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
NCT00834977 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Montreal, Quebec, Canada, H3X H29 SFBC Anapharm Sainte-Foy, Quebec, Canada, G1V 2K8 Collapse << |
NCT00649519 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT00835367 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Montreal, Quebec, Canada, H2X 2H9 SFBC Anapharm Sainte-Foy, Quebec, Canada, G1V 2K8 Collapse << |
NCT00835367 | - | - | Completed | - | - |
NCT00834977 | - | - | Completed | - | - |
NCT01155908 | Healthy | Phase 1 | Completed | - | - |
NCT01155895 | Healthy | Phase 1 | Completed | - | - |
NCT00778726 | Healthy | Not Applicable | Completed | - | United States, North Carolina ... more >> aaiPharma, Inc Chapel Hill, North Carolina, United States, 27517 Collapse << |
NCT01505998 | Fed | Phase 1 | Completed | - | India ... more >> Vimta Labs Ltd. Hyderabad, A.P, India, 500 051 Collapse << |
NCT01506011 | Fasting | Phase 1 | Completed | - | India ... more >> Vimta Labs Ltd. Hyderabad, A.P, India, 500 051 Collapse << |
NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
NCT00170950 | Hypertension | Phase 3 | Terminated(The study was termi... more >>nated early because of significant efficacy results for the primary endpoint in favor of benazepril/amlodipine treatment.) Collapse << | - | United States, New Jersey ... more >> Novartis Pharmaceuticals E. Hanover, New Jersey, United States, 07936 Denmark sites in Denmark Denmark, Denmark Finland sites in Finland Finland, Finland Norway sites in Norway Norway, Norway Sweden sites in Sweden Sweden, Sweden Collapse << |
NCT00000620 | - | - | Completed | - | - |
NCT00170950 | - | - | Terminated(The study was termi... more >>nated early because of significant efficacy results for the primary endpoint in favor of benazepril/amlodipine treatment.) Collapse << | - | - |
NCT00171119 | Hypertension ... more >>Diabetic Nephropathy Collapse << | Phase 4 | Terminated | - | Switzerland ... more >> Novartis Pharmaceuticals Basel, Switzerland Collapse << |
NCT01669434 | - | - | Completed | - | - |
NCT01669434 | Hypotension on Induction | Phase 4 | Completed | - | United States, Nebraska ... more >> University of Nebraska Medical Center Omaha, Nebraska, United States, 68198 Collapse << |
NCT01715584 | Hypertension | Phase 4 | Recruiting | December 31, 2019 | Canada, Ontario ... more >> London Health Sciences Centre - Victoria Campus Recruiting London, Ontario, Canada, N6A 5W9 Contact: Craig J Railton, MD, PhD 519 685 8500 ext 58525 Craig.Railton@lhsc.on.ca Principal Investigator: Craig J Railton, MD, PhD Sub-Investigator: Jonathan Fairbairn, BSc Sub-Investigator: George Nicoloau, MD Sub-Investigator: Robert Gros, PhD Sub-Investigator: Jason Franklin, MD Sub-Investigator: John Yoo, MD Sub-Investigator: Kevin Fung, MD Sub-Investigator: Anthony Nichols, MD Sub-Investigator: Danielle McNeil, MD Collapse << |
NCT01076205 | - | - | Completed | - | - |
NCT01867047 | - | - | Terminated(Following an interi... more >>m analysis the study team felt that there was enough data that showed no significant difference.) Collapse << | - | - |
NCT01603940 | Hypertension ... more >>Diabetes Mellitus Collapse << | Phase 4 | Completed | - | Brazil ... more >> Hospital Universitario Pedro Ernesto Rio de Janeiro, RJ, Brazil, 20551030 Collapse << |
NCT01867047 | Adverse Effects of Angiotensin... more >>-converting-enzyme Inhibitors Hypotension Collapse << | Not Applicable | Terminated(Following an interi... more >>m analysis the study team felt that there was enough data that showed no significant difference.) Collapse << | - | United States, North Carolina ... more >> Duke University Durham, North Carolina, United States, 27710 Collapse << |
NCT01375322 | Hypertension ... more >>Diabetes Mellitus, Type 2 Albuminuria Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Chang Gung Memorial Hospital-Kaohsiung Kaohsiung, Taiwan, 833 Taichung Veterans General Hospital Taichung, Taiwan, 407 Tri-Service General Hospital Taipei, Taiwan, 114 Far Eastern Memorial Hospital Taipei, Taiwan, 220 Collapse << |
NCT00136851 | Hypertension | Phase 4 | Completed | - | United States, New Jersey ... more >> Novartis Pharmaceuticals East Hanover, New Jersey, United States, 07936 Collapse << |
NCT00367978 | Hypertension | Phase 4 | Completed | - | United States, New Jersey ... more >> Novartis Pharmaceuticals Corporation East Hanover, New Jersey, United States, 07936 Collapse << |
NCT01603940 | - | - | Completed | - | - |
NCT00630708 | Renal Insufficiency, Chronic | Not Applicable | Terminated(Significant differe... more >>nces observed between groups.) Collapse << | - | China, Guangdong ... more >> Renal Division, Nanfang Hospital,Southern Medical University Guangzhou, Guangdong, China, 510515 Collapse << |
NCT00907374 | Microalbuminuria | Not Applicable | Completed | - | United States, California ... more >> Charles Drew University Los Angeles, California, United States, 90059 Collapse << |
NCT03591471 | Henoch-Schönlein Purpura Nephr... more >>itis Collapse << | Phase 1 Phase 2 | Recruiting | December 2018 | China, Henan ... more >> Children's Hospital, The First Affiliated Hospital of HUTCM Recruiting Zhengzhou, Henan, China, 450000 Contact: Ying Ding, Director +86-13503840642 dingying3236@sina.com Contact: Xia Zhang, secretary +86-13838276039 zhangxia_125@163.com Principal Investigator: Ying Ding, Director The First Affiliated Hospital of Henan University of Traditional Chinese Medicine Recruiting Zhengzhou, Henan, China, 450000 Contact: Ying Ding, MD +86-371-66221361 dingying3236@sina.com Contact: Xia zhang, MD +86-371-13213210370 ardar123@sina.com Principal Investigator: Jiansheng Li, MD Collapse << |
NCT02532790 | Henoch-Schoenlein Purpura Neph... more >>ritis Collapse << | Phase 2 | Recruiting | July 2020 | China, Jiangsu ... more >> Nanjing Children's Hospital Recruiting Nanjing, Jiangsu, China, 210000 Contact: Aihua Zhang, M.D. +8618951769017 bszah@163.com Collapse << |
NCT00907374 | - | - | Completed | - | - |
NCT01095939 | Renal Alteration | Phase 3 | Completed | - | Switzerland ... more >> Geneva University Hospitals Geneva, Switzerland Centre Hospitalier Universitaire Vaudois Lausanne, Switzerland Collapse << |
NCT01234922 | - | - | Terminated(slow accrual) | - | - |
NCT00834977 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Montreal, Quebec, Canada, H3X H29 SFBC Anapharm Sainte-Foy, Quebec, Canada, G1V 2K8 Collapse << |
NCT02532777 | Henoch-Schoenlein Purpura Neph... more >>ritis Collapse << | Phase 2 | Recruiting | July 2020 | China, Jiangsu ... more >> Nanjing Children's Hospital Recruiting Nanjing, Jiangsu, China, 210000 Contact: Aihua Zhang, M.D. +8618951769017 bszah@163.com Collapse << |
NCT00234871 | Hypertension ... more >>Diabetes Proteinuria Collapse << | Phase 4 | Completed | - | - |
NCT00834977 | - | - | Completed | - | - |
NCT00835367 | - | - | Completed | - | - |
NCT00835367 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Montreal, Quebec, Canada, H2X 2H9 SFBC Anapharm Sainte-Foy, Quebec, Canada, G1V 2K8 Collapse << |
NCT00836537 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
NCT01155895 | Healthy | Phase 1 | Completed | - | - |
NCT00836576 | Healthy | Phase 1 | Completed | - | United States, Missouri ... more >> Gateway Medical Research, Inc. St. Charles, Missouri, United States, 63301 Collapse << |
NCT01234922 | Hypertension ... more >>Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 2 | Terminated(slow accrual) | - | United States, North Carolina ... more >> Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 Collapse << |
NCT00649519 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT00778726 | Healthy | Not Applicable | Completed | - | United States, North Carolina ... more >> aaiPharma, Inc Chapel Hill, North Carolina, United States, 27517 Collapse << |
NCT00778674 | Healthy | Not Applicable | Completed | - | United States, North Carolina ... more >> aaiPharma, Inc. Chapel Hill, North Carolina, United States, 27517 Collapse << |
NCT00649038 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
NCT01155908 | Healthy | Phase 1 | Completed | - | - |
NCT01506011 | Fasting | Phase 1 | Completed | - | India ... more >> Vimta Labs Ltd. Hyderabad, A.P, India, 500 051 Collapse << |
NCT00649597 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
NCT00649402 | Healhty | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT01505998 | Fed | Phase 1 | Completed | - | India ... more >> Vimta Labs Ltd. Hyderabad, A.P, India, 500 051 Collapse << |
靶点 | Description | IC50 |
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