|((2S,2aR,2a1S,3aR,4R,5aR)-2a-(((2S,3R,4S,5S,6R)-6-((苯甲氧基)甲基)-3,4,5-三羟基四氢-2H-吡喃-2-基)氧基)-4-羟基-2-甲基六氢-2H-1,5-二氧杂-2,4-甲基环丁烷[cd]戊烯-2a1-基)苯甲酸甲酯|CsnPharm

CAS No.: 38642-49-8

benzoylpaeoniflorin/苯甲酰芍药苷 Catalog No. CSN13952

Synonyms: 苯甲酰芍药苷

Benzoylpaeoniflorin is a natural product isolated and purified from the root of Paeonia lactiflora Pall. and may treat coronary heart disease by decreasing apoptosis.

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400-920-2911

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技术信息

生物活性

描述Benzoylpaeoniflorin (BP) is a potential therapeutic agent against oxidative stress related Alzheimer's disease^[3]. TGP (The totally-amounted glucosides of paeony), which are made up of paeoniflorin, albiflorin, oxypaeoniflorin as well as benzoylpaeoniflorin) treatment lessened the behavior-based loss shown "in the spontaneous motor activity as well as the potential of falling to rotarod test". Pretreatment with TGP markedly improved motor coordination, striatal dopamine and its metabolite levels. TGP can enhance dopaminergic neuron's cell survival in the SNpc in virtue of the activated cAMP/PKA/CREB factor of growth on inhibiting the pathway of second messenger apoptosis as well^[4]. TGP has some superior features with immune regulation, gentle effect, many indications and few adverse drug reactions. TGP may be a promising anti-inflammatory and immune drug with soft regulation and has more superiority in the treatment of AIDs^[5]. Additionally, paeoniflorin, benzoylpaeoniflorin, mudanpioside C and paeonol can effectively block voltage-operated Ca2+ channels (VOCCs) to exert calcium antagonism^[6].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.7107 mL
- 8.5533 mL
- 17.1067 mL
- 5 mM
- 0.3421 mL
- 1.7107 mL
- 3.4213 mL
- 10 mM
- 0.1711 mL
- 0.8553 mL
- 1.7107 mL

技术信息

CAS号

38642-49-8

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C30H32O12

运输

蓝冰

分子量

584.57

别名

苯甲酰芍药苷

溶解度

DMSO	100.0 mg/mL (171.1 mM)

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