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CAS No.: 174022-42-5

Bevirimat/贝韦立马 Catalog No. CSN18016

Synonyms: PA-457;MPC-4326;YK FH312

Bevirimat is an anti-HIV drug derived from a betulinic acid-like compound, and is believed to inhibit HIV by a so-called maturation inhibition mechanism.

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技术信息

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描述Bevirimat is an anti-HIV drug derived from a betulinic acid-like compound, and is believed to inhibit HIV by a so-called maturation inhibition mechanism.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01026727	HIV Infections	Phase 2	Terminated(For strategic buisn... more >>ess reasons.) Collapse <<	-	-
NCT00967187	HIV Infections	Phase 2	Completed	-	Australia, New South Wales ... more >> AIDS Research Initiative Darlinghurst, New South Wales, Australia, 2010 Holdsworth House Medical Practice Darlinghurst, New South Wales, Australia, 2010 St Vincent's Hospital Darlinghurst, New South Wales, Australia, 2010 Taylor Square Private Clinic Darlinghurst, New South Wales, Australia, 2010 Collapse <<
NCT01097070	HIV-1 Infection	Phase 2	Completed	-	United States, California ... more >> Quest Clinical Research San Francisco, California, United States, 94115 United States, Florida Gary J. Richmond, MD, PA Ft. Lauderdale, Florida, United States, 33316 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Massachusetts Community Research Initiative of New England Boston, Massachusetts, United States, 02215 Collapse <<

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参考文献

[1] Smith PF, Ogundele A, et al. Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection. Antimicrob Agents Chemother. 2007 Oct;51(10):3574-81.
[2] Salzwedel K, Martin DE, et al. Maturation inhibitors: a new therapeutic class targets the virus structure. AIDS Rev. 2007 Jul-Sep;9(3):162-72.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.7099 mL
- 8.5495 mL
- 17.0991 mL
- 5 mM
- 0.3420 mL
- 1.7099 mL
- 3.4198 mL
- 10 mM
- 0.1710 mL
- 0.8550 mL
- 1.7099 mL

技术信息

CAS号	174022-42-5	储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C36H56O6	运输	蓝冰
分子量	584.83	别名	PA-457;MPC-4326;YK FH312;3-O-(3',3'-Dimethylsuccinyl) Betulinic Acid;FH-11327;贝韦立马

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01026727	HIV Infections	Phase 2	Terminated(For strategic buisn... more >>ess reasons.) Collapse <<	-	-
NCT00967187	HIV Infections	Phase 2	Completed	-	Australia, New South Wales ... more >> AIDS Research Initiative Darlinghurst, New South Wales, Australia, 2010 Holdsworth House Medical Practice Darlinghurst, New South Wales, Australia, 2010 St Vincent's Hospital Darlinghurst, New South Wales, Australia, 2010 Taylor Square Private Clinic Darlinghurst, New South Wales, Australia, 2010 Collapse <<
NCT01097070	HIV-1 Infection	Phase 2	Completed	-	United States, California ... more >> Quest Clinical Research San Francisco, California, United States, 94115 United States, Florida Gary J. Richmond, MD, PA Ft. Lauderdale, Florida, United States, 33316 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Massachusetts Community Research Initiative of New England Boston, Massachusetts, United States, 02215 Collapse <<
NCT00511368	HIV Infections	Phase 2	Completed	-	United States, California ... more >> UCLA Medical Center Los Angeles, California, United States, 90035 Quest Clinical Research San Francisco, California, United States, 94115 United States, Colorado University of Colorado Health Science Center Denver, Colorado, United States, 80262 United States, District of Columbia George Washington University Medical Center Washington, District of Columbia, United States, 20037 Whitman-Walker Clinic Washington, District of Columbia, United States, 20037 United States, Florida Gary Richmond Fort Lauderdale, Florida, United States, 33316 Orlando Immunology Center Orlando, Florida, United States, 32803 United States, Georgia AIDS Research Consortium of Atlanta, Inc. Atlanta, Georgia, United States, 30308 United States, Illinois Northwestern University Feinberg School of Medicine Chicago, Illinois, United States, 60611 United States, Massachusetts The Research Insitute Boston, Massachusetts, United States, 02215 United States, North Carolina UNC at Chapel Hill Chapel Hill, North Carolina, United States, 27599 United States, Ohio University Hospitals of Cleveland Cleveland, Ohio, United States, 44106 Ohio State University Medical Center Columbus, Ohio, United States, 43210 United States, Pennsylvania Drexel University College of Medicine Philadelphia, Pennsylvania, United States, 19102 United States, Rhode Island Miriam Hospital/Brown University Providence, Rhode Island, United States, 02906 United States, Texas Central Texas Clinical Research Austin, Texas, United States, 78705 Southwest Infectious Diseases Dallas, Texas, United States, 75204 University of Texas Medical Branch Internal Medicine Galveston, Texas, United States, 77210-4786 Collapse <<

Bevirimat/贝韦立马 Catalog No. CSN18016

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