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CAS No.: 915020-55-2
Synonyms: NVP-BGT226
BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BGT226 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability; apoptotic cell death may ensue. Bax is a member of the proapoptotic Bcl2 family of proteins.
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技术信息
CAS号 | 915020-55-2 | 储存条件 |
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分子式 | C28H25F3N6O2 | 运输 | 蓝冰 | |
分子量 | 534.53 | 别名 | NVP-BGT226 |
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