|1-(2,2-二苯基四氢呋喃-3-基)-N,N-二甲基甲胺盐酸盐|CsnPharm

CAS No.: 195615-84-0

Blarcamesine HCl Catalog No. CSN21074

Synonyms: AVex-73 hydrochloride;AE-37 hydrochloride;AVex-73 HCl

σ1 agonist (IC50 = 860 nM); also displays affinity for muscarinic M1-M4 receptors (Ki values < 500 nM), but not for σ2 receptors. Exhibits neuroprotective effects, prevents tau hyperphosphorylation, and attenuates scopolamine- and (+)-MK 801-induced learning deficits in a mouse model of amyloid toxicity.

规格	价格	促销价格	库存	数量

400-920-2911

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400-920-2911

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技术信息

生物活性

描述σ1 agonist (IC50 = 860 nM); also displays affinity for muscarinic M1-M4 receptors (Ki values < 500 nM), but not for σ2 receptors. Exhibits neuroprotective effects, prevents tau hyperphosphorylation, and attenuates scopolamine- and (+)-MK 801-induced learning deficits in a mouse model of amyloid toxicity.
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.1461 mL
- 15.7307 mL
- 31.4614 mL
- 5 mM
- 0.6292 mL
- 3.1461 mL
- 6.2923 mL
- 10 mM
- 0.3146 mL
- 1.5731 mL
- 3.1461 mL

技术信息

CAS号

195615-84-0

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C19H24ClNO

运输

蓝冰

分子量

317.85

别名

AVex-73 hydrochloride;AE-37 hydrochloride;AVex-73 HCl;Anavex-2-73

溶解度

DMSO	64.0 mg/mL (201.4 mM)
Water	63.0 mg/mL (198.2 mM)
Ethanol	3.0 mg/mL (9.4 mM)

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