CAS No.: 2443767-35-7
BPR1K871 Catalog No. CSN24802
Synonyms: DBPR114
DBPR114 is a potent multi-kinase inhibitor with potent activities against more than 57 oncogenic kinases, including Aurora-A, FLT3, CSF1R, MET, etc. DBPR114 exhibited favorable PK profiles: a long half-life (t1/2 = 23.5 h), moderate clearance and high volume of distribution. Also DBPR114 can effectively inhibit the growth of human acute myeloid leukemia MOLM-13 and MV4-11, MIA PaCa-2, Hep3B, MKN45, Colo205, and NTUB1 solid tumor xenografts in vivo without causing significant body weight loss.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 2443767-35-7 | 储存条件 |
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| 分子式 | C25H28ClN7O2S | 运输 | 蓝冰 | |||||
| 分子量 | 526.05 | 别名 | DBPR114 | |||||
| 溶解度 |
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动物实验配方 |
