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CAS No.: 156161-89-6
Synonyms: BQ-788 (sodium salt);BQ-788 Sodium Salt;BQ-788
BQ-788 sodium salt is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT03679780 | Cardiovascular Diseases ... more >> Cardiovascular Risk Factor Vasoconstriction Collapse << | Phase 1 | Not yet recruiting | October 1, 2019 | United States, Texas ... more >> Engineering Research Building Not yet recruiting Arlington, Texas, United States, 76019 Contact: R. Matthew Brothers, PhD 8172723156 matthew.brothers@uta.edu Contact: John D Akins, MS 8172721835 john.akins@uta.edu Collapse << |
NCT01395329 | Prehypertension ... more >> Hypertension Collapse << | Phase 4 | Completed | - | United States, Colorado ... more >> UC-Boulder Clinical and Translational Research Center Boulder, Colorado, United States, 80309 Collapse << |
NCT01395329 | - | - | Completed | - | - |
实验方案
技术信息
CAS号 | 156161-89-6 | 储存条件 |
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分子式 | C34H50N5NaO7 | 运输 | 蓝冰 | |
分子量 | 663.78 | 别名 | BQ-788 (sodium salt);BQ-788 Sodium Salt;BQ-788 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT03679780 | Cardiovascular Diseases ... more >> Cardiovascular Risk Factor Vasoconstriction Collapse << | Phase 1 | Not yet recruiting | October 1, 2019 | United States, Texas ... more >> Engineering Research Building Not yet recruiting Arlington, Texas, United States, 76019 Contact: R. Matthew Brothers, PhD 8172723156 matthew.brothers@uta.edu Contact: John D Akins, MS 8172721835 john.akins@uta.edu Collapse << |
NCT01395329 | Prehypertension ... more >> Hypertension Collapse << | Phase 4 | Completed | - | United States, Colorado ... more >> UC-Boulder Clinical and Translational Research Center Boulder, Colorado, United States, 80309 Collapse << |
NCT01395329 | - | - | Completed | - | - |
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