3T3-L1 | 5 μg/ml | Function Assay | 30 min | mimics the effects of insulin and causes robust phosphorylation of Akt (Ser 473) and phosphorylation of AS160 (Thr 642 and Ser 588) | 24843827 |
3T3-L1 | 5 μg/ml | Function Assay | 30 min | recapitulates insulin action with respect to regulating Akt activity and AS160 phosphorylation | 24843827 |
3T3-L1 | 5 μg/ml | Function Assay | 30 min | causes reversible redistribution of GLUT4 | 24843827 |
3T3-L1 | 5 μg/ml | Function Assay | 1 h | causes redistribution of GLUT4 but not increase in glucose uptake | 24843827 |
3T3-L1 | 5 μg/ml | Function Assay | 1 h | causes phosphorylation of the FoxO1 transcription factor | 24843827 |
A172 | 10 μg/ml | Function Assay | 4 h | results in the retrograde transport of fluorescent granules | 25239507 |
A549 | - | Growth Inhibition Assay | - | IC50=0.04 μg/ml | 23793342 |
ADF | 10 μM | Function Assay | 16 h | inhibits the ZnCl2-induced translocation of CRT | 24228232 |
ADF | 10 μM | Function Assay | 6 h | impairs the DC activation | 24228232 |
BAECs | 5 μg/ml | Function Assay | 0-4 h | induces the rapid dephosphorylation of eNOS at Ser1179 | 24085225 |
C2C12 | 1 μg/ml | Function Assay | 1 h | abolishes cytokine release from C2C12 myotubes | 26291279 |
Caco-2 | 2.5 μM | Function Assay | 30 min | attenuates the TGF-β1-mediated increase in SERT function | 25954931 |
Colo 205 | 0-5 μg/mL | Growth Inhibition Assay | 48 h | inhibits cell growth in suspension cultures with an estimated IC50 of ~15 ng/mL | 23973996 |
Colo 205 | 0.012-0.025 μg/mL | Function Assay | 14 d | reduces the clonogenicity of Colo 205 CSCs | 23973996 |
Colo 205 | 0.1 μg/mL | Apoptosis Assay | 0-24 h | induces apoptosis of Colo 205 cells in suspension cultures | 23973996 |
Colo 205 | 0.015 μg/mL | Function Assay | 24 h | induces the expression of ER stress-related genes | 23973996 |
Colo 205 | 0.015 μg/mL | Function Assay | 24 h | inhibits the activity of MMPs | 23973996 |
COS | 1 μg/ml | Function Assay | 3 h | completely disperses the AP-1 signal | 25915900 |
COS-1 | 5 µg/ml | Function Assay | 24 h | restricts localization of NB in the perinuclear region | 24671751 |
DF1 | 1 μM | Function Assay | 48 h | disperses the exogenous CSGalNAcT2 protein | 25807054 |
FRT | 5 μg/ml | Function Assay | 2 h | blocks trafficking through the Golgi complex by inhibiting ER-to-Golgi transport | 25767115 |
FRT | 5 μg/ml | Function Assay | 2 h | prevents the increase in cleaved α subunits when [Na+]i was reduced | 25767115 |
H1299 | 10 μg/ml | Function Assay | 24 h | induces autophagy | 25388970 |
H838-KDLKB1 | 30 ng/ml | Function Assay | 12/18 h | increases the protein levels of BiP | 25011082 |
H838-KDLKB1 | 30 ng/ml | Function Assay | 12/18 h | increases the levels of phosphorylated eIF2α (phospho-eIF2α) | 25011082 |
H838-LKB1 | 30 ng/ml | Function Assay | 12/18 h | increases the protein levels of BiP | 25011082 |
HEK293 | 5 μg/ml | Function Assay | 12 h | abolishes CMA-induced CRELD2 secretion | 24687431 |
HEK293/hERG | 10 μM | Function Assay | 1 h | results in a time-dependent reduction mature hERG protein | 25218469 |
HEK293/tau | 5 μM | Function Assay | 1/2/4 h | induces Golgi fragmentation | 24368089 |
HEK293/tau | 5 μM | Function Assay | 3 h | induces tau hyperphosphorylation | 24368089 |
HeLa | 200 ng/ml | Function Assay | 3 h | induces the artificial break-up of the Golgi complex | 25948586 |
HeLa | 5 μg/ml | Function Assay | 3 h | causes nuclear exclusion of the FoxO1 transcription factor and decreases transcription of FoxO1-regulated genes | 24843827 |
HeLa | 2 μM | Function Assay | 2 h | attenuates the TNF-induced secretion of IL-15 | 23950892 |
HEMC-1 | 0.1 µg/ml | Function Assay | 24 h | causes a higher inhibitory effect on exocytosis than nocodazole | 25972759 |
HepG2 | 1 µM | Function Assay | 24 h | decreases the level of PXR mRNA | 25616597 |
HepG2 | 1μg/mL | Function Assay | 3–24 h | increases the level of APE1 in a time-dependent manner | 25026174 |
HepG2 | - | Growth Inhibition Assay | - | IC50<0.001 μg/ml | 23793342 |
HFS | 0-1 μg/ml | Function Assay | 24 h | GLTP expression reaches a plateau at concentrations as low as 0.01 µg/ml | 23894633 |
HFS | 0.01 µg/ml | Function Assay | 24 h | increases the expression of glycosphingolipid synthase genes at 6 h | 23894633 |
HL-60 | - | Growth Inhibition Assay | - | IC50<0.001 μg/ml | 23793342 |
Huh7 | 5 μg/ml | Function Assay | 4 h | abolishes the secretion of intracellular ApoB | 24100140 |
Huh7 | 5 μg/ml | Function Assay | 1 h | causes a significant increase in ApoB-crescents | 24100140 |
Huh7 | 5–10 ng/ml | Function Assay | 12 h | increases ApoB-crescents without inhibiting secretion | 24100140 |
Huh-7 | 1μg/mL | Function Assay | 3–24 h | increases the level of APE1 in a time-dependent manner | 25026174 |
HUVEC | 10 μM | Function Assay | 1 h | abolishes hypoxia-induced release of ATP from apical and basolateral surfaces | 25956988 |
HUVEC | 10 μM | Function Assay | 1 h | increases the number and intensity of fluorescent areas especially in perinuclear space | 25956988 |
IBRS2 | 5 μg/ml | Function Assay | 0.5 h | disrupts the ERGIC and Golgi | 23963534 |
IBRS2 | 5 μg/ml | Function Assay | 0.5 h | enhances FMDV infection | 23963534 |
iPSC-CMs | 500 ng/ml | Function Assay | 48 h | increases the intensity of the higher mobility LAMPs at the cost of the lower mobility species | 25488666 |
KMS-6 | 1 μM | Function Assay | 24 h | exhibits half the secretion of galanin-LI as did the control | 25229126 |
LOVO | - | Growth Inhibition Assay | - | IC50=0.12 μg/ml | 23793342 |
Macrophages | 71 µM | Function Assay | 6 h | inhibits lunasin internalization | 24039740 |
MDA-MB-231 | 0–50 μg/mL | Cell Viability Assay | 48 h | EC50 = 0.016 µg/mL | 25356567 |
MDA-MB-231 | 0.1 μg/mL | Apoptosis Assay | 4 h | induces apoptosis | 25356567 |
MDA-MB-231 | 0.01/0.05 μg/mL | Growth Inhibition Assay | 24 h | increases the fraction of sub-G1 cell debris | 25356567 |
MDA-MB-231 | 0.05–1 μg/mL | Apoptosis Assay | 24 h | induces PARP (poly ADP-ribose polymerase-1) cleavage | 25356567 |
MDA-MB-231 | 0–50 μg/mL | Function Assay | 24 h | inhibits the formation of 3D and 2D colonies | 25356567 |
MDA-MB-435 | - | Growth Inhibition Assay | - | IC50<0.001 μg/ml | 23793342 |
MDMs | 10 μg/ml | Apoptosis Assay | 12/15 h | induces apoptosis | 24556695 |
MEC | 1 μM | Function Assay | 1.5 h | causes a dramatic decrease in the surface VEGFR2 | 25228815 |
MEFs VAMP7 KO | 5 μM | Function Assay | 20 min | causes resident enzymes such as NAGT-GFP, to diffuse back to the ER | 26196023 |
MEFs WT | 5 μM | Function Assay | 20 min | causes resident enzymes such as NAGT-GFP, to diffuse back to the ER | 26196023 |
MKN45 | - | Growth Inhibition Assay | - | IC50<0.001 μg/ml | 23793342 |
nHDFs | 1 μM | Function Assay | 2 h | prevents the assembly of cytosolic coat proteins onto Golgi membranes | 25772616 |
NRK | 200 ng/ml | Function Assay | 4 h | rescues mitotic progression | 25948586 |
OB-6 | 2.7 μM | Apoptosis Assay | 48 h | induces apoptosis | 25532480 |
OVCAR-3 | 1–15 μM | Growth Inhibition Assay | 24 h | induces a loss of cell viability dose dependently | 23826964 |
OVCAR-3 | 1–15 μM | Function Assay | 24 h | induces nuclear damage | 23826964 |
OVCAR-3 | 1-10 μM | Apoptosis Assay | 4 h | induces the activation of apoptosis-related proteins | 23826964 |
OVCAR-3 | 10 μM | Apoptosis Assay | 24 h | induces activation of caspases | 23826964 |
OVCAR-3 | 1–10 μM | Function Assay | 24 h | induces disruption of the mitochondrial transmembrane potential | 23826964 |
OVCAR-3 | 1–10 μM | Function Assay | 24 h | induces formation of reactive oxygen species | 23826964 |
OVCAR-3 | 1–10 μM | Function Assay | 24 h | inhibits cell adhesion and migration | 23826964 |
PC12 | 2 μM | Function Assay | 1 h | inhibits the L-DOPA (20 μM)-induced transient ERK1/2 phosphorylation | 26363191 |
PEXEL-Nluc | 5 mg/mL | Function Assay | 6 h | causes an increase in reporter activity in the parasite | 25392998 |
PMHs | 10–20 μg/ml | Function Assay | 24 h | induced ER stress | 24407242 |
PMHs | 10–20 μg/ml | Apoptosis Assay | 24 h | increases cell death | 24407242 |
PRP | 10 μM | Function Assay | - | abrogates SDF-1α-mediated CXCR7 externalization | 24668750 |
RAW264.7 | 4 μM | Apoptosis Assay | 48 h | attenuates the inhibition of ox-LDL-induced apoptosis and the facilitation of cholesterol efflux by Ac-hE-18A-NH2 | 24639032 |
RBE4 | 2 μM | Apoptosis Assay | 3–24 h | induces apoptosis time dependently | 25128025 |
RBE4 | 2 μM | Function Assay | 3–24 h | increases the XBP1 protein levels after 3 and 6 h of treatment | 25128025 |
RBE4 | 2 μM | Function Assay | 3–24 h | increases active caspase-12 in a time-dependent manner | 25128025 |
RBE4 | 2 μM | Function Assay | 3–24 h | increases the levels of ROS time-dependently | 25128025 |
RBE4 | 2 μM | Function Assay | 3–24 h | induces a delayed depletion of the ER Ca2+ content at 6 h of incubation significantly | 25128025 |
RBE4 | 2 μM | Function Assay | 3–24 h | induces an overload of Ca2+ in the mitochondria in the first 6 h of incubation (p < 0.001) but Ca2+ levels in this organelle decreased after 12 h of incubation | 25128025 |
RKO-HIPK2i | 10 μM | Function Assay | 16 h | inhibits the ZnCl2-induced translocation of CRT | 24228232 |
SMCs | 10 µg/ml | Function Assay | 0-12 h | shows a trend towards a higher concentration of the ER/SR network in the perinuclear area | 26172080 |
SMCs | 10 µg/ml | Function Assay | 0-12 h | causes a transient Ca2+ release from the ER/SR | 26172080 |
SMCs | 1μg/mL | Function Assay | 3 h | accumulates CNPY2 protein in the ER compartment and no longer co-localized with the Golgi marker | 25589425 |
SP-Nluc | 5 mg/mL | Function Assay | 6 h | causes an increase in reporter activity in the parasite | 25392998 |
U373 | 10 μM | Function Assay | 16 h | inhibits the ZnCl2-induced translocation of CRT | 24228232 |