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CAS No.: 97468-37-6

Cephapirin Benzathine Catalog No. CSN23220

Synonyms: 头孢匹林苄星

Cephapirin Benzathine is the benzathine salt form of cephapirin with antibacterial activity. It binds to penicillin-binding proteins located on the inner membrane of the bacterial cell wall.

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生物活性

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技术信息

生物活性

描述Cephapirin Benzathine is the benzathine salt form of cephapirin. Cephapirin Benzathine is the first generation cephalosporin with broad spectrum antibiotic activity. A single treatment with cephapirin benzathine at 40 DPP (postpartum) improved the reproductive performance of buffaloes with subclinical endometritis^[1]. Cephapirin intrauterine treatment in PVD+ (purulent vaginal discharges) cows at 34 DIM (days in milk) considerably improves reproductive performance compared with untreated PVD+ cows^[2]. Intramammary infusion of tilmicosin was equally as effective as cephapirin benzathine in curing IMI caused by Staph. aureus at drying off^[3]. Intramammary infusion of a dry-cow antibiotic preparation containing 300 mg of cephapirin benzathine into 18 Jersey heifers, 10-12 weeks prepartum, resulted in cure rates of existing intramammary infection (IMI) of 96% (24/25), 100% (4/4), and 90% (28/31) for Staphylococcus aureus, Streptococcus species, and Staphylococcus species, respectively. Cure rates of IMI that had been treated with a lactating-cow therapy containing 200 mg cephapirin benzathine at parturition were 62.5% (15/24), 100% (22/22), and 100% (3/3) for Staphylococcus aureus, Streptococcus species, and Staphylococcus species, respectively^[4]. A single treatment with cephapirin or cloprostenol at 20-33 DIM significantly improved the reproductive performance of cows with subclinical endometritis^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 0.9197 mL
- 4.5987 mL
- 9.1973 mL
- 5 mM
- 0.1839 mL
- 0.9197 mL
- 1.8395 mL
- 10 mM
- 0.0920 mL
- 0.4599 mL
- 0.9197 mL

技术信息

CAS号

97468-37-6

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C50H54N8O12S4

运输

蓝冰

分子量

1087.27

别名

头孢匹林苄星

溶解度

DMSO	insoluble
Water	insoluble

动物实验配方

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