CAS No.: 33818-15-4
Citicoline sodium salt/胞磷胆碱钠 Catalog No. CSN22595
Synonyms: Cytidine diphosphate-choline sodium;CDP-Choline sodium;Cytidine 5'-diphosphocholine sodium
Citicoline Sodium is an essential component of cell membrane phospholipids. Citicoline (CDP-choline or cytidinediphosphate choline; cytidine 5′-diphosphocholine) is a complex organic molecule composed of ribose, pyrophosphate, cytosine and choline. Citicoline is very water soluble and has a bioavailability of greater than 90%. Citicoline presented no mitogenic and chemotactic effects on hCMEC/D3; however, it significantly increased wound recovery, spheroid sprouting and strongly induced endothelial tube-like structure formation in Matrigel. Citicoline induced the expression of phospho-extracellular-signal regulated kinase (ERK)-1/2. It protects hCMEC/D3 against cell damage/apoptosis. Citicoline induces angiogenesis and improves survival of human brain microvessel endothelial cells through pathways involving p-ERK1/2, and IRS-1.
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400-920-2911
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tech@csnpharm.cn靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02823106 Ischemic Stroke Phase 1 Withdrawn(Study put on clinica... more >>l hold by FDA. Sponsor decided to no pursue the study.) Collapse << - United States, Kentucky ... more >> University of Kentucky Medical Center Lexington, Kentucky, United States, 40536 Collapse << NCT01591759 Traumatic Brain Injury Phase 2 Withdrawn(Our citicoline suppl... more >>y expired and the exact product has discontinued.) Collapse << - United States, Massachusetts ... more >> McLean Hospital Brain Imaging Center Belmont, Massachusetts, United States, 02478-9106 Collapse <<
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 33818-15-4 | 储存条件 |
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| 分子式 | C14H25N4NaO11P2 | 运输 | 蓝冰 | |||
| 分子量 | 510.31 | 别名 | Cytidine diphosphate-choline sodium;CDP-Choline sodium;Cytidine 5'-diphosphocholine sodium;CDP-choline;Citicoline (sodium salt);Cytidine 5'-diphosphocholine;Flussorex;Gerolin;Logan;Neurotron;Sinkron;Citicoline Sodium;Citicoline Na;胞磷胆碱钠;胆碱钠 | |||
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动物实验配方 |
