CAS No.: 3621-36-1
Columbamine/非洲防己碱 Catalog No. CSN18241
Synonyms: Columbamin;Dehydroisocorypalmine;非洲防己碱
Columbamine is a quaternary isoquinoline alkaloid isolated and purified from the roots of Coptis chinensis Franch, shows strong activity with IC50 48.1 µM and exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells with low toxicity.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Yusoff M, Hamid H, Houghton P. Anticholinesterase inhibitory activity of quaternary alkaloids from Tinospora crispa. Molecules. 2014 Jan 20;19(1):1201-11.
- [2] Bao M, Cao Z, et al. Columbamine suppresses the proliferation and neovascularization of metastatic osteosarcoma U2OS cells with low cytotoxicity. Toxicol Lett. 2012 Dec 17;215(3):174-80.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 3621-36-1 | 储存条件 |
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| 分子式 | C20H20NO4 | 运输 | 蓝冰 | |||
| 分子量 | 338.38 | 别名 | Columbamin;Dehydroisocorypalmine;非洲防己碱 | |||
| 溶解度 |
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动物实验配方 |
