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CAS No.: 1415560-69-8
Synonyms: PF-02341066 hydrochloride;PF-02341066 HCl
Crizotinib HCl is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectivley.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02098954 | Carcinoma, Non-Small Cell Lung... more >> EGFR Gene Mutation Collapse << | Phase 2 | Unknown | December 2016 | China, Hunan ... more >> Hunan Province Tumor Hospital Recruiting Changsha, Hunan, China Contact: Nong Yang, MD +86 731 89762323 yangnong0217@163.com Contact: Ming Zhou, MD +86 731 89762321 zhouming243@gmail.com Principal Investigator: Nong Yang, MD Collapse << |
NCT01994057 | - | - | Recruiting | October 2018 | China, Guangdong ... more >> Cancer Center, Sun Yat-sen University Recruiting Guangzhou, Guangdong, China, 510060 Contact: Shuang Xin, PHD +86 13580479553 xshuang@mail2.sysu.edu.cn Contact: Wei Feng, PHD +86 15521329809 m18356069145@163.com Principal Investigator: Min Huang, Professor Collapse << |
NCT01998126 | Non-small Cell Lung Cancer | Phase 1 | Completed | - | United States, Utah ... more >> Huntsman Cancer Institute Salt Lake City, Utah, United States, 84112 Collapse << |
实验方案
技术信息
CAS号 | 1415560-69-8 | 储存条件 |
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分子式 | C21H23Cl3FN5O | 运输 | 蓝冰 | |
分子量 | 486.80 | 别名 | PF-02341066 hydrochloride;PF-02341066 HCl |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02098954 | Carcinoma, Non-Small Cell Lung... more >> EGFR Gene Mutation Collapse << | Phase 2 | Unknown | December 2016 | China, Hunan ... more >> Hunan Province Tumor Hospital Recruiting Changsha, Hunan, China Contact: Nong Yang, MD +86 731 89762323 yangnong0217@163.com Contact: Ming Zhou, MD +86 731 89762321 zhouming243@gmail.com Principal Investigator: Nong Yang, MD Collapse << |
NCT01994057 | - | - | Recruiting | October 2018 | China, Guangdong ... more >> Cancer Center, Sun Yat-sen University Recruiting Guangzhou, Guangdong, China, 510060 Contact: Shuang Xin, PHD +86 13580479553 xshuang@mail2.sysu.edu.cn Contact: Wei Feng, PHD +86 15521329809 m18356069145@163.com Principal Investigator: Min Huang, Professor Collapse << |
NCT01998126 | Non-small Cell Lung Cancer | Phase 1 | Completed | - | United States, Utah ... more >> Huntsman Cancer Institute Salt Lake City, Utah, United States, 84112 Collapse << |
NCT01801111 | Non-Small-Cell Lung Carcinoma | Phase 1 Phase 2 | Completed | - | - |
NCT01801111 | - | - | Completed | - | - |
NCT00965731 | Non-Small Cell Lung Cancer | Phase 1 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California University of California, Irvine Medical Center Pharmacy Orange, California, United States, 92868-3298 University of California, Irving - Medical Center Orange, California, United States, 92868-3298 University of California Irvin Orange, California, United States, 92868 United States, Florida Holy Cross Hospital Fort Lauderdale, Florida, United States, 33308 United States, Missouri Siteman Cancer Center -West County Creve Coeur, Missouri, United States, 63141 Barnes-Jewish Hospital St. Louis, Missouri, United States, 63110-1094 Washington University, School of Medicine St. Louis, Missouri, United States, 63110 Siteman Cancer Center St. Peters, Missouri, United States, 63376 United States, Ohio OSU East Columbus, Ohio, United States, 43205 The Ohio State University James Cancer Hospital Columbus, Ohio, United States, 43210 James Care in Kenny Columbus, Ohio, United States, 43221 United States, Texas Cancer Therapy & Research Center @ UTHSCSA San Antonio, Texas, United States, 78229 United States, Washington Seattle Cancer Care Alliance Seattle, Washington, United States, 98109 University of Washington Medical Center Seattle, Washington, United States, 98195 Collapse << |
NCT02194738 | Large Cell Lung Carcinoma ... more >> Lung Adenocarcinoma Stage IB Non-Small Cell Lung Carcinoma AJCC v7 Stage IB Squamous Cell Lung Carcinoma AJCC v7 Stage II Non-Small Cell Lung Cancer AJCC v7 Stage II Squamous Cell Lung Carcinoma AJCC v7 Stage IIA Non-Small Cell Lung Carcinoma AJCC v7 Stage IIA Squamous Cell Lung Carcinoma AJCC v7 Stage IIB Non-Small Cell Lung Carcinoma AJCC v7 Stage IIB Squamous Cell Lung Carcinoma AJCC v7 Stage IIIA Non-Small Cell Lung Cancer AJCC v7 Stage IIIA Squamous Cell Lung Carcinoma AJCC v7 Collapse << | Phase 3 | Recruiting | - | - |
NCT01979536 | Anaplastic Large Cell Lymphoma... more >>, ALK-Positive Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell Lymphoma CD30-Positive Neoplastic Cells Present Collapse << | Phase 2 | Recruiting | December 31, 2021 | - |
NCT00965731 | - | - | Completed | - | - |
NCT01606878 | Recurrent Childhood Anaplastic... more >> Large Cell Lymphoma Recurrent Neuroblastoma Unspecified Childhood Solid Tumor, Protocol Specific Collapse << | Phase 1 | Active, not recruiting | - | - |
NCT02277457 | Non-Small Cell Lung Cancer | Early Phase 1 | Withdrawn | - | United States, Michigan ... more >> University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48187 Collapse << |
NCT01822496 | Stage III Non-Small Cell Lung ... more >>Cancer AJCC v7 Stage IIIA Non-Small Cell Lung Cancer AJCC v7 Stage IIIB Non-Small Cell Lung Cancer AJCC v7 Collapse << | Phase 2 | Terminated | - | - |
NCT03126916 | Childhood Ganglioneuroblastoma... more >> Childhood Neuroblastoma INRG Stage L2 INRG Stage M INRG Stage MS NMYC Gene Amplification Recurrent Neuroblastoma Collapse << | Phase 3 | Recruiting | June 30, 2026 | - |
NCT02551718 | Acute Leukemia of Ambiguous Li... more >>neage Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Recurrent Childhood Acute Lymphoblastic Leukemia Recurrent Childhood Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia Refractory Adult Acute Lymphoblastic Leukemia Refractory Childhood Acute Lymphoblastic Leukemia Collapse << | Not Applicable | Recruiting | - | United States, Washington ... more >> Fred Hutch/University of Washington Cancer Consortium Recruiting Seattle, Washington, United States, 98109 Contact: Pamela S. Becker 206-616-1589 pbecker@u.washington.edu Principal Investigator: Pamela S. Becker Collapse << |
NCT01979536 | Anaplastic Large Cell Lymphoma... more >>, ALK-Positive Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell Lymphoma CD30-Positive Neoplastic Cells Present Collapse << | Phase 2 | Recruiting | December 31, 2021 | - |
NCT03126916 | Childhood Ganglioneuroblastoma... more >> Childhood Neuroblastoma INRG Stage L2 INRG Stage M INRG Stage MS NMYC Gene Amplification Recurrent Neuroblastoma Collapse << | Phase 3 | Recruiting | June 30, 2026 | - |
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