CAS No.: 1028385-32-1
Dactolisib Tosylate Catalog No. CSN17405
Synonyms: BEZ235 Tosylate;NVP-BEZ 235 Tosylate;NV BEZ-235 Tosylate
BEZ235 tosylate is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Matsushima M, Kikuchi E, et al. Intravesical dual PI3K/mTOR complex 1/2 inhibitor NVP-BEZ235 therapy in an orthotopic bladder cancer model. Int J Oncol. 2015 Jul;47(1):377-83.
- [2] Gobin B, Battaglia S, et al. NVP-BEZ235, a dual PI3K/mTOR inhibitor, inhibits osteosarcoma cell proliferation and tumor development in vivo with an improved survival rate. Cancer Lett. 2014 Mar 28;344(2):291-8. doi: 10.1016/j.canlet.2013.11.017. Epub 2013 Dec 11. PubMed PMID: 24333720.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1028385-32-1 | 储存条件 |
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| 分子式 | C37H31N5O4S | 运输 | 蓝冰 | |
| 分子量 | 641.74 | 别名 | BEZ235 Tosylate;NVP-BEZ 235 Tosylate;NV BEZ-235 Tosylate;Dactolisib tosylate;NVP-BEZ235-ANA;UNII-U54GT9151S |
