|3-(((5-(4-硝基苯基)呋喃-2-基)亚甲基)氨基)-2,5-二氧代咪唑啉-1-鎓钠盐|CsnPharm

CAS No.: 14663-23-1

Dantrolene sodium/丹曲林钠盐 Catalog No. CSN17111

Synonyms: F 440;Dantrolene (sodium salt)

Dantrolene sodium is an inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm.

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靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Dantrolene sodium is an inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00812851	Cramps Amyotr... more >>ophic Lateral Sclerosis Collapse <<	Not Applicable	Completed	-	Switzerland ... more >> Kantonsspital St.Gallen St.Gallen, Switzerland, 9007 Collapse <<
NCT01244113	Cerebral Palsy	Not Applicable	Completed	-	Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Collapse <<
NCT00964548	Cerebral Vasospasm After Subar... more >>achnoid Hemorrhage Collapse <<	Phase 1 Phase 2	Completed	-	United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 UMASS Memorial Medical Center/UMASS Medical School Worcester, Massachusetts, United States, 01655 Collapse <<

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参考文献

[1] Rosado IR, Lavor MS, et al. Effects of methylprednisolone, dantrolene, and their combination on experimental spinal cord injury. Int J Clin Exp Pathol. 2014 Jul 15;7(8):4617-26. eCollection 2014.
[2] Kim JY, Chun S, et al. Safety of low-dose oral dantrolene sodium on hepatic function. Arch Phys Med Rehabil. 2011 Sep;92(9):1359-63.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.9741 mL
- 14.8706 mL
- 29.7411 mL
- 5 mM
- 0.5948 mL
- 2.9741 mL
- 5.9482 mL
- 10 mM
- 0.2974 mL
- 1.4871 mL
- 2.9741 mL

技术信息

CAS号

14663-23-1

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C14H9N4NaO5

运输

蓝冰

分子量

336.23

别名

F 440;Dantrolene (sodium salt)

溶解度

DMSO	67.0 mg/mL (199.3 mM)

动物实验配方

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT00812851	Cramps Amyotr... more >>ophic Lateral Sclerosis Collapse <<	Not Applicable	Completed	-	Switzerland ... more >> Kantonsspital St.Gallen St.Gallen, Switzerland, 9007 Collapse <<
NCT01244113	Cerebral Palsy	Not Applicable	Completed	-	Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Collapse <<
NCT00964548	Cerebral Vasospasm After Subar... more >>achnoid Hemorrhage Collapse <<	Phase 1 Phase 2	Completed	-	United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 UMASS Memorial Medical Center/UMASS Medical School Worcester, Massachusetts, United States, 01655 Collapse <<
NCT00964548	-	-	Completed	-	-
NCT00796900	Hyperthermia	Phase 2 Phase 3	Terminated(organizationally no... more >>t possible) Collapse <<	-	Austria ... more >> Medical University Vienna Vienna, Austria, 1090 Collapse <<
NCT03762109	Lumbar Spine Injury	Phase 2	Not yet recruiting	December 31, 2020	-
NCT01024972	-	-	Completed	-	-
NCT03600376	Exertional Heat Stroke	Phase 3	Completed	-	Saudi Arabia ... more >> King Faisal Hospital Mecca, Saudi Arabia Mina al Jisr Hospital Mina, Saudi Arabia Mina Al-Shari Al-Jadeed Hospital Mina, Saudi Arabia Mina Al-Wadi Hospital Mina, Saudi Arabia Collapse <<
NCT02829268	Wolfram Syndrome ... more >> Diabetes Mellitus Optic Nerve Atrophy Ataxia Collapse <<	Phase 1 Phase 2	Recruiting	March 2021	United States, Missouri ... more >> Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Ashley Simpson, RN, BSN, CPN 314-286-1550 ashley.simpson@wustl.edu Contact: Fumihiko Urano, MD 314-362-8683 urano@wustl.edu Principal Investigator: Fumihiko Urano, MD Collapse <<
NCT02513095	-	-	Completed	-	-
NCT01024972	Subarachnoid Hemorrhage ... more >> Cerebral Vasospasm Collapse <<	Phase 1 Phase 2	Completed	-	United States, Massachusetts ... more >> UMASS Medical School / UMass Memorial Medical Center Worcester, Massachusetts, United States, 01655 Collapse <<
NCT02513095	Heat Stroke	Phase 2	Completed	-	Saudi Arabia ... more >> Mecca, Saudi Arabia Collapse <<
NCT03189433	Drug Toxicity Psychotropic Age... more >>nts Psychostimulants Collapse <<	Phase 2	Active, not recruiting	December 2018	United States, Maryland ... more >> CrowdRx Medical Office- Moonrise Festival Baltimore, Maryland, United States, 21215 Collapse <<

Dantrolene sodium/丹曲林 钠盐 Catalog No. CSN17111

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Dantrolene sodium/丹曲林钠盐 Catalog No. CSN17111