|(2R,3R,4S,5S,6R)-2-(((2R,4aS,4bR,7S,10aS)-7-((R)-1,2-二羟基乙基)-1,1,4a,7-四甲基-1,2,3,4,4a,4b,5,6,7,9,10,10a-十二氢菲-2-基)氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇|CsnPharm

CAS No.: 59219-65-7

Synonyms: 豨莶苷

Darutoside is a diterpenoid isolated from Siegesbeckia.

规格	价格	促销价格	库存	数量

400-920-2911

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描述Darutoside is a diterpenoid isolated from Siegesbeckia. Five diterpenoids were obtained from the fraction D_(50) with the strongest PPARγ activity among others in SPA (Siegesbeckia pubescens), and determined as kirenol(1), darutigenol(2), enantiomeric-2-ketone-15,16,19-three hydroxypinomane-8(14) -ene-19- O-β-D- glucoside(3), darutoside(4), enantiomeric-2-β,15,16,19-four hydroxypinomane-8(14)-ene-19-O-β-D-glucoside(5), respectively. All the compounds exhibited active effects on PPARγ in a concentration-dependent manner. The diterpenoids 1-5 isolated from S. pubescens have the PPARγ activation activities and potential effects of anti-UC in vitro^[2]. Three diterpenes including a new compound were isolated from the whole plant of Siegesbeckia glabrescens Mak. The new one was named as neodarutoside and its structure was elucidated as ent-3 alpha, 15,16-trihydroxy pimarane 3,15-bis-(beta-glucopyranoside) based on the spectral evidence and chemical transformation. Darutoside possesses the activity of termination of early pregnancy in experimental rats at a dosage of 20-40 mg/kg^[3].
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CAS号	59219-65-7	储存条件	粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C26H44O8	运输	蓝冰
分子量	484.62	别名	豨莶苷

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