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CAS No.: 166023-21-8
Synonyms: DC-Cholesterol hydrochloride;DC-Chol (hydrochloride);Cholesteryl 3β-N-(dimethylaminoethyl)carbamate
DC-Chol is a cationic cholesterol derivative. DC-Chol, as a component of lipoplexes with DOPE, has been used for transfection of mRNA into A549 cells without affecting cell viability. Incubation of DC-chol/DOPE liposomes or lipoplexes with human whole blood has no effect on neutrophil elastase or β-thromboglobulin levels or the number of platelets and red and white blood cells, indicating hemocompatibility. DC-Chol has also been widely used in the synthesis of liposomes for the delivery of siRNA, DNA, and chemotherapeutic agents into cells and mice.
生物活性
实验方案
技术信息
CAS号 | 166023-21-8 | 储存条件 |
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分子式 | C32H57ClN2O2 | 运输 | 蓝冰 | |
分子量 | 537.26 | 别名 | DC-Cholesterol hydrochloride;DC-Chol (hydrochloride);Cholesteryl 3β-N-(dimethylaminoethyl)carbamate;DC-Cholesterol HCl |
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