CAS No.: 251945-92-3
Derenofylline Catalog No. CSN23120
Synonyms: SLV 320
Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats[1].
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00568009 - - Terminated(additional enrolmen... more >>t criteria made patients' recruitment not feasible anymore) Collapse << November 2008 - NCT00160134 Congestive Heart Failure Phase 2 Completed - Germany ... more >> Site 1 Bad Nauheim, Germany Collapse << NCT00744341 Acute Decompensated Heart Fail... more >>ure; Renal Dysfunction Collapse << Phase 2 Terminated(This study was stop... more >>ped 29OCT2009 due to strategic drug development considerations) Collapse << - -
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 251945-92-3 | 储存条件 |
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| 分子式 | C18H20N4O | 运输 | 蓝冰 | |||
| 分子量 | 308.38 | 别名 | SLV 320 | |||
| 溶解度 |
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动物实验配方 |
