CAS No.: 28610-31-3
Desmethylicaritin Catalog No. CSN14303
Synonyms: Desmethyl icaritin;Noranhydroicartin;4'-Desmethylicaritin
8-Prenylkaempferol, a natural product isolated and purified from the roots of Sophora flavescens, is an effective agent for attenuating pro-inflammatory NO induction, induces differentiation/maturation of MC3T3-E1 osteoblasts by BMP-2/p38/Runx2 pathways, and may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and IRF-3 and in part by interfering with IκB degradation which subsequently decreases NF-κB translocation.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Chiou WF, Chen CC, Wei BL. 8-Prenylkaempferol Suppresses Influenza A Virus-Induced RANTES Production in A549 Cells via Blocking PI3K-Mediated Transcriptional Activation of NF-κB and IRF3. Evid Based Complement Alternat Med. 2011;2011:920828.
- [2] Chiou WF, Lee CH, et al. 8-Prenylkaempferol accelerates osteoblast maturation through bone morphogenetic protein-2/p38 pathway to activate Runx2 transcription. Life Sci. 2011 Feb 14;88(7-8):335-42.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 28610-31-3 | 储存条件 |
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| 分子式 | C20H18O6 | 运输 | 蓝冰 | |
| 分子量 | 354.35 | 别名 | Desmethyl icaritin;Noranhydroicartin;4'-Desmethylicaritin;8-C-Prenylkaempferol |
