9011-18-1|Dextran sulfate sodium|CsnPharm

CAS No.: 9011-18-1

硫酸葡聚糖钠盐 Catalog No. CSN27369

Synonyms: DSS;硫酸葡聚糖钠盐;葡聚糖硫酸钠盐

Dextran sulfate sodium salt (MW ~40,000) is a is a polymer of anhydroglucose with the molecular weight range of ~40,000. Dextran sulfate sodium salt inhibits the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells.

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描述Dextran sulfate sodium salt (MW ~40,000) is a is a polymer of anhydroglucose with the molecular weight range of ~40,000. Dextran sulfate sodium salt inhibits the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells. The molecular weight of DSS to be an important factor in the murine model of colitis. In the 5 kD group, colitis was observed predominantly in the cecum and upper colon. Colitis in the 40 kD group was more severe than that in the 5 kD group, and in the 40 kD group it was more severe in the lower colon than in the upper colon.
参考文献

[1] Baba M, et al. Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6132-6.
[2] Kitajima S, Takuma S, Morimoto M. Histological analysis of murine colitis induced by dextran sulfate sodium of different molecular weights. Exp Anim. 2000 Jan;49(1):9-15. doi: 10.1538/expanim.49.9. PMID: 10803356.

实验方案

计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号	9011-18-1	储存条件	粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6 月 -80°C:12月
分子式	(C₆H₇Na₃O₁₄S₃)n	运输	蓝冰
分子量	N/A	别名	DSS;硫酸葡聚糖钠盐;葡聚糖硫酸钠盐

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